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Items: 1 to 20 of 99


Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice.

Panici JA, Harper JM, Miller RA, Bartke A, Spong A, Masternak MM.

FASEB J. 2010 Dec;24(12):5073-9. doi: 10.1096/fj.10-163253. Epub 2010 Aug 18.


Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress.

Salmon AB, Murakami S, Bartke A, Kopchick J, Yasumura K, Miller RA.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E23-9. Epub 2005 Feb 8.


Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.

Ungvari Z, Sosnowska D, Podlutsky A, Koncz P, Sonntag WE, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2011 May;66(5):501-10. doi: 10.1093/gerona/glr004. Epub 2011 Feb 24.


Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant.

Vergara M, Smith-Wheelock M, Harper JM, Sigler R, Miller RA.

J Gerontol A Biol Sci Med Sci. 2004 Dec;59(12):1244-50.


Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

Rojanathammanee L, Rakoczy S, Brown-Borg HM.

J Gerontol A Biol Sci Med Sci. 2014 Oct;69(10):1199-211. doi: 10.1093/gerona/glt178. Epub 2013 Nov 27.


The effects of growth hormone (GH) treatment on GH and insulin/IGF-1 signaling in long-lived Ames dwarf mice.

Masternak MM, Panici JA, Wang F, Wang Z, Spong A.

J Gerontol A Biol Sci Med Sci. 2010 Jan;65(1):24-30. doi: 10.1093/gerona/glp172. Epub 2009 Nov 11.


Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.

Csiszar A, Labinskyy N, Perez V, Recchia FA, Podlutsky A, Mukhopadhyay P, Losonczy G, Pacher P, Austad SN, Bartke A, Ungvari Z.

Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H1882-94. doi: 10.1152/ajpheart.412.2008. Epub 2008 Aug 29.


Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

Gesing A, Al-Regaiey KA, Bartke A, Masternak MM.

Exp Gerontol. 2014 Oct;58:219-29. doi: 10.1016/j.exger.2014.08.010. Epub 2014 Aug 21.


Life extension in the dwarf mouse.

Bartke A, Brown-Borg H.

Curr Top Dev Biol. 2004;63:189-225. Review.


Ames dwarf (Prop1(df)/Prop1(df)) mice display increased sensitivity of the major GH-signaling pathways in liver and skeletal muscle.

Miquet JG, Muñoz MC, Giani JF, González L, Dominici FP, Bartke A, Turyn D, Sotelo AI.

Growth Horm IGF Res. 2010 Apr;20(2):118-26. doi: 10.1016/j.ghir.2009.11.003. Epub 2009 Dec 21.


Thyroxine modifies the effects of growth hormone in Ames dwarf mice.

Do A, Menon V, Zhi X, Gesing A, Wiesenborn DS, Spong A, Sun L, Bartke A, Masternak MM.

Aging (Albany NY). 2015 Apr;7(4):241-55.


Long-lived ames dwarf mice are resistant to chemical stressors.

Bokov AF, Lindsey ML, Khodr C, Sabia MR, Richardson A.

J Gerontol A Biol Sci Med Sci. 2009 Aug;64(8):819-27. doi: 10.1093/gerona/glp052. Epub 2009 May 4.


Hepatic response to oxidative injury in long-lived Ames dwarf mice.

Sun LY, Bokov AF, Richardson A, Miller RA.

FASEB J. 2011 Jan;25(1):398-408. doi: 10.1096/fj.10-164376. Epub 2010 Sep 8.


Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice.

Leiser SF, Salmon AB, Miller RA.

Mech Ageing Dev. 2006 Nov;127(11):821-9. Epub 2006 Sep 18.


Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.

Ungvari Z, Gautam T, Koncz P, Henthorn JC, Pinto JT, Ballabh P, Yan H, Mitschelen M, Farley J, Sonntag WE, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1145-56. doi: 10.1093/gerona/glq147. Epub 2010 Aug 16.


Enhanced growth and immune development in dwarf chickens treated with mammalian growth hormone and thyroxine.

Marsh JA, Gause WC, Sandhu S, Scanes CG.

Proc Soc Exp Biol Med. 1984 Mar;175(3):351-60.

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