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Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.

Zhang T, Mi Z, Schor NF.

Oxid Med Cell Longev. 2009 Sep-Oct;2(4):238-46. doi: 10.4161/oxim.2.4.9745.


Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.

Costantini C, Rossi F, Formaggio E, Bernardoni R, Cecconi D, Della-Bianca V.

J Mol Neurosci. 2005;25(2):141-56.


Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle.

Vilar M, Murillo-Carretero M, Mira H, Magnusson K, Besset V, Ibáñez CF.

EMBO J. 2006 Mar 22;25(6):1219-30. Epub 2006 Feb 23.


Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro.

Hatchett CS, Tyler S, Armstrong D, Dawbarn D, Allen SJ.

Brain Res. 2007 May 25;1147:248-55. Epub 2007 Feb 7.


p75 neurotrophin receptor is implicated in the ability of neurotrophin-3 to negatively modulate activated ERK1/2 signaling in TrkA-expressing adult sensory neurons.

Wilson-Gerwing TD, Johnston JM, Verge VM.

J Comp Neurol. 2009 Sep 1;516(1):49-58. doi: 10.1002/cne.22098.


Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J.

Neuroscience. 2002;115(4):1089-108.


The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling.

Ceni C, Kommaddi RP, Thomas R, Vereker E, Liu X, McPherson PS, Ritter B, Barker PA.

J Cell Sci. 2010 Jul 1;123(Pt 13):2299-307. doi: 10.1242/jcs.062612. Epub 2010 Jun 8.


Carprofen induction of p75NTR-dependent apoptosis via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.

Khwaja FS, Quann EJ, Pattabiraman N, Wynne S, Djakiew D.

Mol Cancer Ther. 2008 Nov;7(11):3539-45. doi: 10.1158/1535-7163.MCT-08-0512. Epub 2008 Oct 30.


Apoptosis related protein-1 triggers melanoma cell death via interaction with the juxtamembrane region of p75 neurotrophin receptor.

Selimovic D, Sprenger A, Hannig M, Haïkel Y, Hassan M.

J Cell Mol Med. 2012 Feb;16(2):349-61. doi: 10.1111/j.1582-4934.2011.01304.x.


Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability.

Kanning KC, Hudson M, Amieux PS, Wiley JC, Bothwell M, Schecterson LC.

J Neurosci. 2003 Jul 2;23(13):5425-36.


The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway.

Roux PP, Bhakar AL, Kennedy TE, Barker PA.

J Biol Chem. 2001 Jun 22;276(25):23097-104. Epub 2001 Apr 18.


Resveratrol attenuates oxidative stress induced by balloon injury in the rat carotid artery through actions on the ERK1/2 and NF-kappa B pathway.

Zhang J, Chen J, Yang J, Xu CW, Pu P, Ding JW, Jiang H.

Cell Physiol Biochem. 2013;31(2-3):230-41. doi: 10.1159/000343364. Epub 2013 Feb 14.


Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells.

Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Müller-Esterl W, Zeuzem S.

J Biol Chem. 2002 Nov 15;277(46):43623-30. Epub 2002 Sep 5.


p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.

Forsyth PA, Krishna N, Lawn S, Valadez JG, Qu X, Fenstermacher DA, Fournier M, Potthast L, Chinnaiyan P, Gibney GT, Zeinieh M, Barker PA, Carter BD, Cooper MK, Kenchappa RS.

J Biol Chem. 2014 Mar 21;289(12):8067-85. doi: 10.1074/jbc.M113.513762. Epub 2014 Feb 11.


Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain.

Srinivasan B, Wang Z, Brun-Zinkernagel AM, Collier RJ, Black RA, Frank SJ, Barker PA, Roque RS.

Mol Cell Neurosci. 2007 Dec;36(4):449-61. Epub 2007 Aug 15.


Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors.

Volonté C, Angelastro JM, Greene LA.

J Biol Chem. 1993 Oct 5;268(28):21410-5.


IL-10 attenuates TNF-alpha-induced NF kappaB pathway activation and cardiomyocyte apoptosis.

Dhingra S, Sharma AK, Arora RC, Slezak J, Singal PK.

Cardiovasc Res. 2009 Apr 1;82(1):59-66. doi: 10.1093/cvr/cvp040. Epub 2009 Jan 30.


Tanshinone IIA inhibits LPS-induced NF-kappaB activation in RAW 264.7 cells: possible involvement of the NIK-IKK, ERK1/2, p38 and JNK pathways.

Jang SI, Kim HJ, Kim YJ, Jeong SI, You YO.

Eur J Pharmacol. 2006 Aug 7;542(1-3):1-7. Epub 2006 May 6.

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