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Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis.

Godin JD, Colombo K, Molina-Calavita M, Keryer G, Zala D, Charrin BC, Dietrich P, Volvert ML, Guillemot F, Dragatsis I, Bellaiche Y, Saudou F, Nguyen L, Humbert S.

Neuron. 2010 Aug 12;67(3):392-406. doi: 10.1016/j.neuron.2010.06.027.


Mitotic spindle: focus on the function of huntingtin.

Godin JD, Humbert S.

Int J Biochem Cell Biol. 2011 Jun;43(6):852-6. doi: 10.1016/j.biocel.2011.03.009. Epub 2011 Mar 23. Review.


Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex.

Molina-Calavita M, Barnat M, Elias S, Aparicio E, Piel M, Humbert S.

J Neurosci. 2014 Jul 23;34(30):10034-40. doi: 10.1523/JNEUROSCI.0715-14.2014.


Huntingtin regulates mammary stem cell division and differentiation.

Elias S, Thion MS, Yu H, Sousa CM, Lasgi C, Morin X, Humbert S.

Stem Cell Reports. 2014 Apr 3;2(4):491-506. doi: 10.1016/j.stemcr.2014.02.011. eCollection 2014 Apr 8.


CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.

Yang Y, Liu M, Li D, Ran J, Gao J, Suo S, Sun SC, Zhou J.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2158-63. doi: 10.1073/pnas.1319341111. Epub 2014 Jan 27.


Aurora A contributes to p150(glued) phosphorylation and function during mitosis.

Romé P, Montembault E, Franck N, Pascal A, Glover DM, Giet R.

J Cell Biol. 2010 May 17;189(4):651-9. doi: 10.1083/jcb.201001144.


Role of NuMA in vertebrate cells: review of an intriguing multifunctional protein.

Sun QY, Schatten H.

Front Biosci. 2006 Jan 1;11:1137-46. Review.


The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells.

Maier B, Kirsch M, Anderhub S, Zentgraf H, Krämer A.

Cell Cycle. 2013 May 1;12(9):1457-71. doi: 10.4161/cc.24602. Epub 2013 Apr 10.


Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes.

Gaglio T, Dionne MA, Compton DA.

J Cell Biol. 1997 Sep 8;138(5):1055-66.


Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.

Yumoto T, Nakadate K, Nakamura Y, Sugitani Y, Sugitani-Yoshida R, Ueda S, Sakakibara S.

PLoS One. 2013 Nov 8;8(11):e79895. doi: 10.1371/journal.pone.0079895. eCollection 2013.


Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

Gaglio T, Saredi A, Bingham JB, Hasbani MJ, Gill SR, Schroer TA, Compton DA.

J Cell Biol. 1996 Oct;135(2):399-414.


Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.

Sakai D, Dixon J, Dixon MJ, Trainor PA.

PLoS Genet. 2012;8(3):e1002566. doi: 10.1371/journal.pgen.1002566. Epub 2012 Mar 29.


Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells.

Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD.

Nat Neurosci. 2009 Jun;12(6):735-44. doi: 10.1038/nn.2339. Epub 2009 May 17.


Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.

Yingling J, Youn YH, Darling D, Toyo-Oka K, Pramparo T, Hirotsune S, Wynshaw-Boris A.

Cell. 2008 Feb 8;132(3):474-86. doi: 10.1016/j.cell.2008.01.026.


Analysis of Huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons.

Martin EJ, Kim M, Velier J, Sapp E, Lee HS, Laforet G, Won L, Chase K, Bhide PG, Heller A, Aronin N, Difiglia M.

J Comp Neurol. 1999 Jan 25;403(4):421-30.


[Huntington's disease: intracellular signaling pathways and neuronal death].

Humbert S, Saudou F.

J Soc Biol. 2005;199(3):247-51. Review. French.


Protein 4.1R, a microtubule-associated protein involved in microtubule aster assembly in mammalian mitotic extract.

Huang SC, Jagadeeswaran R, Liu ES, Benz EJ Jr.

J Biol Chem. 2004 Aug 13;279(33):34595-602. Epub 2004 Jun 7.


Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control.

Siller KH, Serr M, Steward R, Hays TS, Doe CQ.

Mol Biol Cell. 2005 Nov;16(11):5127-40. Epub 2005 Aug 17.


A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation.

Chen CT, Hehnly H, Yu Q, Farkas D, Zheng G, Redick SD, Hung HF, Samtani R, Jurczyk A, Akbarian S, Wise C, Jackson A, Bober M, Guo Y, Lo C, Doxsey S.

Curr Biol. 2014 Oct 6;24(19):2327-34. doi: 10.1016/j.cub.2014.08.029. Epub 2014 Sep 11. Erratum in: Curr Biol. 2014 Dec 15;24(24):2975. Curr Biol. 2014 Oct 6;24(19):2354.

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