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Items: 1 to 20 of 143

1.

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J 2nd, Liu G, Spira A, Bell DA.

PLoS One. 2010 Aug 3;5(8):e11934. doi: 10.1371/journal.pone.0011934.

2.

Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk.

Wang X, Pittman GS, Bandele OJ, Bischof JJ, Liu G, Brothers JF 2nd, Spira A, Bell DA.

Hum Genet. 2014 Dec;133(12):1467-76. doi: 10.1007/s00439-014-1483-8. Epub 2014 Sep 2.

3.

Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.

Hirotsu Y, Katsuoka F, Funayama R, Nagashima T, Nishida Y, Nakayama K, Engel JD, Yamamoto M.

Nucleic Acids Res. 2012 Nov 1;40(20):10228-39. doi: 10.1093/nar/gks827. Epub 2012 Sep 10.

4.

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.

Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A.

BMC Genomics. 2008 May 30;9:259. doi: 10.1186/1471-2164-9-259.

5.

Bronchial airway gene expression in smokers with lung or head and neck cancer.

Van Dyck E, Nazarov PV, Muller A, Nicot N, Bosseler M, Pierson S, Van Moer K, Palissot V, Mascaux C, Knolle U, Ninane V, Nati R, Bremnes RM, Vallar L, Berchem G, Schlesser M.

Cancer Med. 2014 Apr;3(2):322-36. doi: 10.1002/cam4.190. Epub 2014 Feb 4.

6.

Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq.

Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A.

Cancer Prev Res (Phila). 2011 Jun;4(6):803-17. doi: 10.1158/1940-6207.CAPR-11-0212.

7.

Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer.

Boelens MC, van den Berg A, Fehrmann RS, Geerlings M, de Jong WK, te Meerman GJ, Sietsma H, Timens W, Postma DS, Groen HJ.

J Pathol. 2009 Jun;218(2):182-91. doi: 10.1002/path.2520.

PMID:
19334046
8.

Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers.

Zhang L, Lee JJ, Tang H, Fan YH, Xiao L, Ren H, Kurie J, Morice RC, Hong WK, Mao L.

Cancer Prev Res (Phila). 2008 Jul;1(2):112-8. doi: 10.1158/1940-6207.CAPR-07-0017. Epub 2008 Mar 31.

9.

Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer.

Butler MW, Fukui T, Salit J, Shaykhiev R, Mezey JG, Hackett NR, Crystal RG.

Cancer Res. 2011 Apr 1;71(7):2572-81. doi: 10.1158/0008-5472.CAN-10-2046. Epub 2011 Feb 16.

10.

Relation between smoking history and gene expression profiles in lung adenocarcinomas.

Staaf J, Jönsson G, Jönsson M, Karlsson A, Isaksson S, Salomonsson A, Pettersson HM, Soller M, Ewers SB, Johansson L, Jönsson P, Planck M.

BMC Med Genomics. 2012 Jun 7;5:22.

11.

Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking.

Hübner RH, Schwartz JD, De Bishnu P, Ferris B, Omberg L, Mezey JG, Hackett NR, Crystal RG.

Mol Med. 2009 Jul-Aug;15(7-8):203-19. doi: 10.2119/molmed.2008.00130. Epub 2009 Mar 20.

12.

Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers.

Wang G, Xu Z, Wang R, Al-Hijji M, Salit J, Strulovici-Barel Y, Tilley AE, Mezey JG, Crystal RG.

BMC Med Genomics. 2012 Jun 7;5:21. doi: 10.1186/1755-8794-5-21.

13.

Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.

Katsuoka F, Motohashi H, Engel JD, Yamamoto M.

J Biol Chem. 2005 Feb 11;280(6):4483-90. Epub 2004 Dec 1.

14.

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue.

Beane J, Cheng L, Soldi R, Zhang X, Liu G, Anderlind C, Lenburg ME, Spira A, Bild AH.

Cancer Res. 2012 Nov 15;72(22):5702-11. doi: 10.1158/0008-5472.CAN-12-1043. Epub 2012 Sep 17.

15.

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium.

Zhang X, Sebastiani P, Liu G, Schembri F, Zhang X, Dumas YM, Langer EM, Alekseyev Y, O'Connor GT, Brooks DR, Lenburg ME, Spira A.

Physiol Genomics. 2010 Mar 3;41(1):1-8. doi: 10.1152/physiolgenomics.00167.2009. Epub 2009 Dec 1.

16.

Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers.

Woenckhaus M, Klein-Hitpass L, Grepmeier U, Merk J, Pfeifer M, Wild P, Bettstetter M, Wuensch P, Blaszyk H, Hartmann A, Hofstaedter F, Dietmaier W.

J Pathol. 2006 Oct;210(2):192-204.

PMID:
16915569
17.

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer.

Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, Keane J, Lenburg ME, Brody JS.

Nat Med. 2007 Mar;13(3):361-6. Epub 2007 Mar 4.

PMID:
17334370
18.

Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.

Rotunno M, Yu K, Lubin JH, Consonni D, Pesatori AC, Goldstein AM, Goldin LR, Wacholder S, Welch R, Burdette L, Chanock SJ, Bertazzi PA, Tucker MA, Caporaso NE, Chatterjee N, Bergen AW, Landi MT.

PLoS One. 2009 May 21;4(5):e5652. doi: 10.1371/journal.pone.0005652.

19.

Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.

Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A.

PLoS One. 2009;4(4):e5043. doi: 10.1371/journal.pone.0005043. Epub 2009 Apr 9.

20.

Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers.

Hackett NR, Heguy A, Harvey BG, O'Connor TP, Luettich K, Flieder DB, Kaplan R, Crystal RG.

Am J Respir Cell Mol Biol. 2003 Sep;29(3 Pt 1):331-43. Epub 2003 Apr 17.

PMID:
12702543
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