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Items: 1 to 20 of 104

1.

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, Peng J, Cheng D, Sui G, Kaiser UB, Shi Y, Shi YG.

Mol Cell. 2010 Jul 30;39(2):222-33. doi: 10.1016/j.molcel.2010.07.008.

2.

Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b.

Zhang Q, Qi S, Xu M, Yu L, Tao Y, Deng Z, Wu W, Li J, Chen Z, Wong J.

Cell Res. 2013 Feb;23(2):225-41. doi: 10.1038/cr.2012.177. Epub 2012 Dec 25.

3.

Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.

Katz TA, Vasilatos SN, Harrington E, Oesterreich S, Davidson NE, Huang Y.

Breast Cancer Res Treat. 2014 Jul;146(1):99-108. doi: 10.1007/s10549-014-3012-9. Epub 2014 Jun 13.

PMID:
24924415
4.

Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).

Mino K, Nishimura S, Ninomiya S, Tujii H, Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, Sasaki R, Murakami-Yamaguchi Y, Narita H, Suzuki T, Miyata N, Mizukami T.

Biosci Biotechnol Biochem. 2014;78(6):1010-7. doi: 10.1080/09168451.2014.910104. Epub 2014 Jun 13.

PMID:
25036127
5.

LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.

Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y, Shi YG.

Mol Cell. 2013 Feb 7;49(3):558-70. doi: 10.1016/j.molcel.2012.11.019. Epub 2012 Dec 20.

6.

Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.

Kim DH, Tang Z, Shimada M, Fierz B, Houck-Loomis B, Bar-Dagen M, Lee S, Lee SK, Muir TW, Roeder RG, Lee JW.

Mol Cell Biol. 2013 Dec;33(24):4936-46. doi: 10.1128/MCB.00601-13. Epub 2013 Oct 14.

7.

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.

Guccione E, Bassi C, Casadio F, Martinato F, Cesaroni M, Schuchlautz H, L├╝scher B, Amati B.

Nature. 2007 Oct 18;449(7164):933-7. Epub 2007 Sep 26.

PMID:
17898714
8.

Histone demethylase LSD2 acts as an E3 ubiquitin ligase and inhibits cancer cell growth through promoting proteasomal degradation of OGT.

Yang Y, Yin X, Yang H, Xu Y.

Mol Cell. 2015 Apr 2;58(1):47-59. doi: 10.1016/j.molcel.2015.01.038. Epub 2015 Mar 12.

9.

The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.

Tang M, Shen H, Jin Y, Lin T, Cai Q, Pinard MA, Biswas S, Tran Q, Li G, Shenoy AK, Tongdee E, Lin S, Gu Y, Law BK, Zhou L, McKenna R, Wu L, Lu J.

J Biol Chem. 2013 Sep 20;288(38):27680-91. doi: 10.1074/jbc.M113.482349. Epub 2013 Aug 8.

10.

A novel mammalian flavin-dependent histone demethylase.

Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A.

J Biol Chem. 2009 Jun 26;284(26):17775-82. doi: 10.1074/jbc.M109.003087. Epub 2009 Apr 30.

11.

Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression.

Mersman DP, Du HN, Fingerman IM, South PF, Briggs SD.

J Biol Chem. 2012 Jan 20;287(4):2652-65. doi: 10.1074/jbc.M111.280867. Epub 2011 Dec 6.

12.

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K.

J Biol Chem. 2007 Jul 13;282(28):20395-406. Epub 2007 May 11.

13.

Structure and function of histone H3 lysine 9 methyltransferases and demethylases.

Krishnan S, Horowitz S, Trievel RC.

Chembiochem. 2011 Jan 24;12(2):254-63. doi: 10.1002/cbic.201000545. Epub 2011 Jan 5. Review.

PMID:
21243713
14.

Coexpression of nuclear receptors and histone methylation modifying genes in the testis: implications for endocrine disruptor modes of action.

Anderson AM, Carter KW, Anderson D, Wise MJ.

PLoS One. 2012;7(4):e34158. doi: 10.1371/journal.pone.0034158. Epub 2012 Apr 4.

15.

Nitric oxide modifies global histone methylation by inhibiting Jumonji C domain-containing demethylases.

Hickok JR, Vasudevan D, Antholine WE, Thomas DD.

J Biol Chem. 2013 May 31;288(22):16004-15. doi: 10.1074/jbc.M112.432294. Epub 2013 Apr 1.

16.

Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.

Chaturvedi CP, Somasundaram B, Singh K, Carpenedo RL, Stanford WL, Dilworth FJ, Brand M.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18845-50. doi: 10.1073/pnas.1213951109. Epub 2012 Oct 29.

17.

[Advances in histone methyltransferases and histone demethylases].

Wang X, Zhu WG.

Ai Zheng. 2008 Oct;27(10):1018-25. Review. Chinese.

PMID:
18851779
18.

Selective targeting of histone methylation.

Islam AB, Richter WF, Lopez-Bigas N, Benevolenskaya EV.

Cell Cycle. 2011 Feb 1;10(3):413-24. Epub 2011 Feb 1.

19.

A core chromatin remodeling factor instructs global chromatin signaling through multivalent reading of nucleosome codes.

Nair SS, Li DQ, Kumar R.

Mol Cell. 2013 Feb 21;49(4):704-18. doi: 10.1016/j.molcel.2012.12.016. Epub 2013 Jan 24.

20.

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.

Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A.

Nature. 2010 Jul 15;466(7304):383-7. doi: 10.1038/nature09195. Epub 2010 Jun 16.

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