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L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice.

Imaizumi S, Grijalva V, Navab M, Van Lenten BJ, Wagner AC, Anantharamiah GM, Fogelman AM, Reddy ST.

Drug Metab Lett. 2010 Aug;4(3):139-48.


Apolipoprotein E mimetic is more effective than apolipoprotein A-I mimetic in reducing lesion formation in older female apo E null mice.

Nayyar G, Garber DW, Palgunachari MN, Monroe CE, Keenum TD, Handattu SP, Mishra VK, Anantharamaiah GM.

Atherosclerosis. 2012 Oct;224(2):326-31. doi: 10.1016/j.atherosclerosis.2012.05.040. Epub 2012 Jun 23.


Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma.

Meriwether D, Imaizumi S, Grijalva V, Hough G, Vakili L, Anantharamaiah GM, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST, Shechter I.

J Lipid Res. 2011 Oct;52(10):1795-809. doi: 10.1194/jlr.M016741. Epub 2011 Jul 29.


Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio.

Navab M, Hama-Levy S, Van Lenten BJ, Fonarow GC, Cardinez CJ, Castellani LW, Brennan ML, Lusis AJ, Fogelman AM, La Du BN.

J Clin Invest. 1997 Apr 15;99(8):2005-19. Erratum in: J Clin Invest 1997 Jun 15;99(12):3043.


Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes.

Morgantini C, Natali A, Boldrini B, Imaizumi S, Navab M, Fogelman AM, Ferrannini E, Reddy ST.

Diabetes. 2011 Oct;60(10):2617-23. doi: 10.2337/db11-0378. Epub 2011 Aug 18.


L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation.

Buga GM, Navab M, Imaizumi S, Reddy ST, Yekta B, Hough G, Chanslor S, Anantharamaiah GM, Fogelman AM.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):283-9. doi: 10.1161/ATVBAHA.109.200162. Epub 2009 Dec 3. Erratum in: Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):e174. Dosage error in article text.


Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice.

Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Wagner AC, Frank JS, Datta G, Garber D, Fogelman AM.

Circulation. 2004 Jun 29;109(25):3215-20. Epub 2004 Jun 14.


Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes.

Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST.

Diabetes. 2010 Dec;59(12):3223-8. doi: 10.2337/db10-0844. Epub 2010 Sep 8.


A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids.

Navab M, Hama SY, Hough GP, Subbanagounder G, Reddy ST, Fogelman AM.

J Lipid Res. 2001 Aug;42(8):1308-17.


Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling.

Nieman DC, Shanely RA, Luo B, Meaney MP, Dew DA, Pappan KL.

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 1;307(1):R68-74. doi: 10.1152/ajpregu.00092.2014. Epub 2014 Apr 23.


Varying the ratio of dietary n-6/n-3 polyunsaturated fatty acid alters the tendency to thrombosis and progress of atherosclerosis in apoE-/- LDLR-/- double knockout mouse.

Yamashita T, Oda E, Sano T, Yamashita T, Ijiru Y, Giddings JC, Yamamoto J.

Thromb Res. 2005;116(5):393-401. Epub 2005 Feb 25.


Quantitative trait locus analysis of atherosclerosis in an intercross between C57BL/6 and C3H mice carrying the mutant apolipoprotein E gene.

Su Z, Li Y, James JC, McDuffie M, Matsumoto AH, Helm GA, Weber JL, Lusis AJ, Shi W.

Genetics. 2006 Mar;172(3):1799-807. Epub 2005 Dec 30.


4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice.

Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS.

FASEB J. 2011 Jan;25(1):290-300. doi: 10.1096/fj.10-165670. Epub 2010 Sep 27.


An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice.

Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Wagner AC, Hama S, Hough G, Bachini E, Garber DW, Mishra VK, Palgunachari MN, Fogelman AM.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1932-7. Epub 2005 Jun 16.


The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis.

Staprans I, Pan XM, Rapp JH, Feingold KR.

Mol Nutr Food Res. 2005 Nov;49(11):1075-82. Review.


Synthetic low and high fat diets for the study of atherosclerosis in the mouse.

Nishina PM, Verstuyft J, Paigen B.

J Lipid Res. 1990 May;31(5):859-69.

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