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Results: 1 to 20 of 90

1.

Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.

Rosen SD, Lemjabbar-Alaoui H.

Expert Opin Ther Targets. 2010 Sep;14(9):935-49. doi: 10.1517/14728222.2010.504718. Review.

PMID:
20629619
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

Lemjabbar-Alaoui H, van Zante A, Singer MS, Xue Q, Wang YQ, Tsay D, He B, Jablons DM, Rosen SD.

Oncogene. 2010 Feb 4;29(5):635-46. doi: 10.1038/onc.2009.365. Epub 2009 Oct 26.

PMID:
19855436
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells.

Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD.

PLoS One. 2007 Apr 25;2(4):e392.

PMID:
17460759
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.

Lamanna WC, Frese MA, Balleininger M, Dierks T.

J Biol Chem. 2008 Oct 10;283(41):27724-35. doi: 10.1074/jbc.M802130200. Epub 2008 Aug 6.

PMID:
18687675
[PubMed - indexed for MEDLINE]
Free Article
5.

The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.

Maltseva I, Chan M, Kalus I, Dierks T, Rosen SD.

PLoS One. 2013 Aug 8;8(8):e69642. doi: 10.1371/journal.pone.0069642. eCollection 2013.

PMID:
23950901
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Use of a phage display antibody to measure the enzymatic activity of the Sulfs.

Uchimura K, Lemjabbar-Alaoui H, van Kuppevelt TH, Rosen SD.

Methods Enzymol. 2010;480:51-64. doi: 10.1016/S0076-6879(10)80003-5. Review.

PMID:
20816204
[PubMed - indexed for MEDLINE]
7.

Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.

Tran TH, Shi X, Zaia J, Ai X.

J Biol Chem. 2012 Sep 21;287(39):32651-64. Epub 2012 Aug 3.

PMID:
22865881
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Roles of heparan sulfate sulfation in dentinogenesis.

Hayano S, Kurosaka H, Yanagita T, Kalus I, Milz F, Ishihara Y, Islam MN, Kawanabe N, Saito M, Kamioka H, Adachi T, Dierks T, Yamashiro T.

J Biol Chem. 2012 Apr 6;287(15):12217-29. doi: 10.1074/jbc.M111.332924. Epub 2012 Feb 20.

PMID:
22351753
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Morimoto-Tomita M, Uchimura K, Bistrup A, Lum DH, Egeblad M, Boudreau N, Werb Z, Rosen SD.

Neoplasia. 2005 Nov;7(11):1001-10.

PMID:
16331886
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

Lai J, Chien J, Staub J, Avula R, Greene EL, Matthews TA, Smith DI, Kaufmann SH, Roberts LR, Shridhar V.

J Biol Chem. 2003 Jun 20;278(25):23107-17. Epub 2003 Apr 9.

PMID:
12686563
[PubMed - indexed for MEDLINE]
Free Article
11.

Functional consequences of the subdomain organization of the sulfs.

Tang R, Rosen SD.

J Biol Chem. 2009 Aug 7;284(32):21505-14. doi: 10.1074/jbc.M109.028472. Epub 2009 Jun 11.

PMID:
19520866
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Glycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2.

Staples GO, Shi X, Zaia J.

PLoS One. 2011 Feb 8;6(2):e16689. doi: 10.1371/journal.pone.0016689.

PMID:
21347431
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.

Lum DH, Tan J, Rosen SD, Werb Z.

Mol Cell Biol. 2007 Jan;27(2):678-88. Epub 2006 Nov 20.

PMID:
17116694
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Matrix detachment and proteasomal inhibitors diminish Sulf-2 expression in breast cancer cell lines and mouse xenografts.

Khurana A, Jung-Beom D, He X, Kim SH, Busby RC, Lorenzon L, Villa M, Baldi A, Molina J, Goetz MP, Shridhar V.

Clin Exp Metastasis. 2013 Apr;30(4):407-15. doi: 10.1007/s10585-012-9546-5. Epub 2013 Feb 15.

PMID:
23412907
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling.

Cole CL, Rushton G, Jayson GC, Avizienyte E.

J Biol Chem. 2014 Apr 11;289(15):10488-501. doi: 10.1074/jbc.M113.534263. Epub 2014 Feb 22.

PMID:
24563483
[PubMed - indexed for MEDLINE]
16.

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.

Li J, Kleeff J, Abiatari I, Kayed H, Giese NA, Felix K, Giese T, Büchler MW, Friess H.

Mol Cancer. 2005 Apr 7;4(1):14.

PMID:
15817123
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.

Nagamine S, Tamba M, Ishimine H, Araki K, Shiomi K, Okada T, Ohto T, Kunita S, Takahashi S, Wismans RG, van Kuppevelt TH, Masu M, Keino-Masu K.

J Biol Chem. 2012 Mar 16;287(12):9579-90. doi: 10.1074/jbc.M111.290262. Epub 2012 Feb 1.

PMID:
22298771
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.

Helfrich BA, Raben D, Varella-Garcia M, Gustafson D, Chan DC, Bemis L, Coldren C, Barón A, Zeng C, Franklin WA, Hirsch FR, Gazdar A, Minna J, Bunn PA Jr.

Clin Cancer Res. 2006 Dec 1;12(23):7117-25.

PMID:
17145836
[PubMed - indexed for MEDLINE]
Free Article
19.

Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.

Langsdorf A, Schumacher V, Shi X, Tran T, Zaia J, Jain S, Taglienti M, Kreidberg JA, Fine A, Ai X.

Glycobiology. 2011 Feb;21(2):152-61. doi: 10.1093/glycob/cwq133. Epub 2010 Sep 20.

PMID:
20855470
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.

Otsuki S, Taniguchi N, Grogan SP, D'Lima D, Kinoshita M, Lotz M.

Arthritis Res Ther. 2008;10(3):R61. doi: 10.1186/ar2432. Epub 2008 May 28.

PMID:
18507859
[PubMed - indexed for MEDLINE]
Free PMC Article
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