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Results: 1 to 20 of 89

1.

Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells.

Hervouet E, Lalier L, Debien E, Cheray M, Geairon A, Rogniaux H, Loussouarn D, Martin SA, Vallette FM, Cartron PF.

PLoS One. 2010 Jun 29;5(6):e11333. doi: 10.1371/journal.pone.0011333.

PMID:
20613874
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures.

Pacaud R, Brocard E, Lalier L, Hervouet E, Vallette FM, Cartron PF.

Sci Rep. 2014 Mar 18;4:4230. doi: 10.1038/srep04230.

PMID:
24637615
[PubMed - in process]
Free PMC Article
3.

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1.

Qin W, Leonhardt H, Spada F.

J Cell Biochem. 2011 Feb;112(2):439-44. doi: 10.1002/jcb.22998.

PMID:
21268065
[PubMed - indexed for MEDLINE]
4.

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.

Liu X, Gao Q, Li P, Zhao Q, Zhang J, Li J, Koseki H, Wong J.

Nat Commun. 2013;4:1563. doi: 10.1038/ncomms2562.

PMID:
23463006
[PubMed - indexed for MEDLINE]
5.

PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA.

Iida T, Suetake I, Tajima S, Morioka H, Ohta S, Obuse C, Tsurimoto T.

Genes Cells. 2002 Oct;7(10):997-1007.

PMID:
12354094
[PubMed - indexed for MEDLINE]
6.

UHRF1 plays a role in maintaining DNA methylation in mammalian cells.

Bostick M, Kim JK, Estève PO, Clark A, Pradhan S, Jacobsen SE.

Science. 2007 Sep 21;317(5845):1760-4. Epub 2007 Aug 2.

PMID:
17673620
[PubMed - indexed for MEDLINE]
Free Article
7.

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance.

Zhang J, Gao Q, Li P, Liu X, Jia Y, Wu W, Li J, Dong S, Koseki H, Wong J.

Cell Res. 2011 Dec;21(12):1723-39. doi: 10.1038/cr.2011.176. Epub 2011 Nov 8.

PMID:
22064703
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.

Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A.

J Biol Chem. 2014 Feb 14;289(7):4106-15. doi: 10.1074/jbc.M113.528893. Epub 2013 Dec 24.

PMID:
24368767
[PubMed - indexed for MEDLINE]
9.

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.

Felle M, Joppien S, Németh A, Diermeier S, Thalhammer V, Dobner T, Kremmer E, Kappler R, Längst G.

Nucleic Acids Res. 2011 Oct;39(19):8355-65. doi: 10.1093/nar/gkr528. Epub 2011 Jul 10.

PMID:
21745816
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16 INK4A re-expression related to UHRF1 and DNMT1 down-regulation.

Krifa M, Alhosin M, Muller CD, Gies JP, Chekir-Ghedira L, Ghedira K, Mély Y, Bronner C, Mousli M.

J Exp Clin Cancer Res. 2013 May 20;32:30. doi: 10.1186/1756-9966-32-30.

PMID:
23688286
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.

Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, Endo TA, Shinga J, Mizutani-Koseki Y, Toyoda T, Okamura K, Tajima S, Mitsuya K, Okano M, Koseki H.

Nature. 2007 Dec 6;450(7171):908-12. Epub 2007 Nov 11.

PMID:
17994007
[PubMed - indexed for MEDLINE]
12.

UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma.

Mudbhary R, Hoshida Y, Chernyavskaya Y, Jacob V, Villanueva A, Fiel MI, Chen X, Kojima K, Thung S, Bronson RT, Lachenmayer A, Revill K, Alsinet C, Sachidanandam R, Desai A, SenBanerjee S, Ukomadu C, Llovet JM, Sadler KC.

Cancer Cell. 2014 Feb 10;25(2):196-209. doi: 10.1016/j.ccr.2014.01.003. Epub 2014 Jan 30.

PMID:
24486181
[PubMed - indexed for MEDLINE]
13.

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.

Jin W, Chen L, Chen Y, Xu SG, Di GH, Yin WJ, Wu J, Shao ZM.

Breast Cancer Res Treat. 2010 Sep;123(2):359-73. doi: 10.1007/s10549-009-0652-2. Epub 2009 Nov 27.

PMID:
19943104
[PubMed - indexed for MEDLINE]
14.

Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation.

Sun L, Zhao H, Xu Z, Liu Q, Liang Y, Wang L, Cai X, Zhang L, Hu L, Wang G, Zha X.

Cell Signal. 2007 Nov;19(11):2255-63. Epub 2007 Jun 29.

PMID:
17716861
[PubMed - indexed for MEDLINE]
15.

Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1.

Achour M, Mousli M, Alhosin M, Ibrahim A, Peluso J, Muller CD, Schini-Kerth VB, Hamiche A, Dhe-Paganon S, Bronner C.

Biochem Biophys Res Commun. 2013 Jan 4;430(1):208-12. doi: 10.1016/j.bbrc.2012.11.087. Epub 2012 Nov 28.

PMID:
23201574
[PubMed - indexed for MEDLINE]
16.

Decrease of DNA methyltransferase 1 expression relative to cell proliferation in transitional cell carcinoma.

Kimura F, Seifert HH, Florl AR, Santourlidis S, Steinhoff C, Swiatkowski S, Mahotka C, Gerharz CD, Schulz WA.

Int J Cancer. 2003 May 1;104(5):568-78.

PMID:
12594811
[PubMed - indexed for MEDLINE]
17.

UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity.

Achour M, Fuhrmann G, Alhosin M, Rondé P, Chataigneau T, Mousli M, Schini-Kerth VB, Bronner C.

Biochem Biophys Res Commun. 2009 Dec 18;390(3):523-8. doi: 10.1016/j.bbrc.2009.09.131. Epub 2009 Oct 2.

PMID:
19800870
[PubMed - indexed for MEDLINE]
18.

Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells.

Ji W, Yang L, Yu L, Yuan J, Hu D, Zhang W, Yang J, Pang Y, Li W, Lu J, Fu J, Chen J, Lin Z, Chen W, Zhuang Z.

Carcinogenesis. 2008 Jun;29(6):1267-75. doi: 10.1093/carcin/bgn012. Epub 2008 Jan 19.

PMID:
18204074
[PubMed - indexed for MEDLINE]
Free Article
19.

Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens.

Tittle RK, Sze R, Ng A, Nuckels RJ, Swartz ME, Anderson RM, Bosch J, Stainier DY, Eberhart JK, Gross JM.

Dev Biol. 2011 Feb 1;350(1):50-63. doi: 10.1016/j.ydbio.2010.11.009. Epub 2010 Nov 30.

PMID:
21126517
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression.

Cartron PF, Blanquart C, Hervouet E, Gregoire M, Vallette FM.

Mol Oncol. 2013 Jun;7(3):452-63. doi: 10.1016/j.molonc.2012.11.004. Epub 2012 Dec 21.

PMID:
23312906
[PubMed - indexed for MEDLINE]
Free Article

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