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Items: 1 to 20 of 236

1.

A new DAF-16 isoform regulates longevity.

Kwon ES, Narasimhan SD, Yen K, Tissenbaum HA.

Nature. 2010 Jul 22;466(7305):498-502. doi: 10.1038/nature09184. Epub 2010 Jul 7.

2.

SMK-1, an essential regulator of DAF-16-mediated longevity.

Wolff S, Ma H, Burch D, Maciel GA, Hunter T, Dillin A.

Cell. 2006 Mar 10;124(5):1039-53.

3.

PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.

Narasimhan SD, Yen K, Bansal A, Kwon ES, Padmanabhan S, Tissenbaum HA.

PLoS Genet. 2011 Apr;7(4):e1001377. doi: 10.1371/journal.pgen.1001377. Epub 2011 Apr 21.

4.

Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity.

Zhang Y, Xu J, Puscau C, Kim Y, Wang X, Alam H, Hu PJ.

Dev Biol. 2008 Mar 15;315(2):290-302. doi: 10.1016/j.ydbio.2007.12.032. Epub 2008 Jan 3.

5.

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.

Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M.

Genes Dev. 2008 Oct 1;22(19):2721-35. doi: 10.1101/gad.478408.

6.

Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans.

Honda Y, Tanaka M, Honda S.

Exp Gerontol. 2008 Jun;43(6):520-9. doi: 10.1016/j.exger.2008.02.009. Epub 2008 Mar 18.

PMID:
18406553
7.
8.

EAK proteins: novel conserved regulators of C. elegans lifespan.

Williams TW, Dumas KJ, Hu PJ.

Aging (Albany NY). 2010 Oct;2(10):742-7.

9.

The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation.

Warnhoff K, Murphy JT, Kumar S, Schneider DL, Peterson M, Hsu S, Guthrie J, Robertson JD, Kornfeld K.

PLoS Genet. 2014 Oct 16;10(10):e1004703. doi: 10.1371/journal.pgen.1004703. eCollection 2014 Oct.

10.

RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans.

Seo M, Seo K, Hwang W, Koo HJ, Hahm JH, Yang JS, Han SK, Hwang D, Kim S, Jang SK, Lee Y, Nam HG, Lee SJ.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4246-55. doi: 10.1073/pnas.1505451112. Epub 2015 Jul 20.

11.

Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.

Li J, Ebata A, Dong Y, Rizki G, Iwata T, Lee SS.

PLoS Biol. 2008 Sep 30;6(9):e233. doi: 10.1371/journal.pbio.0060233.

12.

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

Takahashi Y, Daitoku H, Hirota K, Tamiya H, Yokoyama A, Kako K, Nagashima Y, Nakamura A, Shimada T, Watanabe S, Yamagata K, Yasuda K, Ishii N, Fukamizu A.

Cell Metab. 2011 May 4;13(5):505-16. doi: 10.1016/j.cmet.2011.03.017.

13.

Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation.

Chen AT, Guo C, Dumas KJ, Ashrafi K, Hu PJ.

Aging Cell. 2013 Oct;12(5):932-40. doi: 10.1111/acel.12120. Epub 2013 Jul 19.

14.

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling.

Lin K, Hsin H, Libina N, Kenyon C.

Nat Genet. 2001 Jun;28(2):139-45.

PMID:
11381260
15.

Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans.

Rahman MM, Stuchlick O, El-Karim EG, Stuart R, Kipreos ET, Wells L.

Aging (Albany NY). 2010 Oct;2(10):678-90.

16.

DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.

Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D.

PLoS Genet. 2014 Feb 6;10(2):e1004109. doi: 10.1371/journal.pgen.1004109. eCollection 2014 Feb.

17.

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.

Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G.

Nature. 1997 Oct 30;389(6654):994-9.

PMID:
9353126
18.

pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans.

Monje JM, Brokate-Llanos AM, Pérez-Jiménez MM, Fidalgo MA, Muñoz MJ.

Aging Cell. 2011 Dec;10(6):1021-31. doi: 10.1111/j.1474-9726.2011.00747.x.

19.

14-3-3 regulates life span by both DAF-16-dependent and -independent mechanisms in Caenorhabditis elegans.

Araiz C, Château MT, Galas S.

Exp Gerontol. 2008 Jun;43(6):505-19. doi: 10.1016/j.exger.2008.03.001. Epub 2008 Mar 18.

PMID:
18423931
20.

Co-regulation of the DAF-16 target gene, cyp-35B1/dod-13, by HSF-1 in C. elegans dauer larvae and daf-2 insulin pathway mutants.

Iser WB, Wilson MA, Wood WH 3rd, Becker K, Wolkow CA.

PLoS One. 2011 Mar 9;6(3):e17369. doi: 10.1371/journal.pone.0017369.

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