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Results: 1 to 20 of 180

1.

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

Cooper O, Hargus G, Deleidi M, Blak A, Osborn T, Marlow E, Lee K, Levy A, Perez-Torres E, Yow A, Isacson O.

Mol Cell Neurosci. 2010 Nov;45(3):258-66. doi: 10.1016/j.mcn.2010.06.017. Epub 2010 Jul 24.

PMID:
20603216
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons.

Rössler R, Boddeke E, Copray S.

Neuroscience. 2010 Oct 13;170(2):417-28. doi: 10.1016/j.neuroscience.2010.07.023. Epub 2010 Jul 17.

PMID:
20643196
[PubMed - indexed for MEDLINE]
3.

Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons.

Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, Moore M, Osborn T, Cooper O, Spealman R, Hallett P, Isacson O.

Stem Cells. 2013 Aug;31(8):1548-62. doi: 10.1002/stem.1415.

PMID:
23666606
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells.

Jaeger I, Arber C, Risner-Janiczek JR, Kuechler J, Pritzsche D, Chen IC, Naveenan T, Ungless MA, Li M.

Development. 2011 Oct;138(20):4363-74. doi: 10.1242/dev.066746. Epub 2011 Aug 31.

PMID:
21880784
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Generation of dopamine neurons from embryonic stem cells in the presence of the neuralizing activity of bone marrow stromal cells derived from adult mice.

Shintani A, Nakao N, Kakishita K, Itakura T.

J Neurosci Res. 2008 Oct;86(13):2829-38. doi: 10.1002/jnr.21748.

PMID:
18561325
[PubMed - indexed for MEDLINE]
6.

In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons.

Park CH, Minn YK, Lee JY, Choi DH, Chang MY, Shim JW, Ko JY, Koh HC, Kang MJ, Kang JS, Rhie DJ, Lee YS, Son H, Moon SY, Kim KS, Lee SH.

J Neurochem. 2005 Mar;92(5):1265-76.

PMID:
15715675
[PubMed - indexed for MEDLINE]
7.

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.

Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, Studer L.

Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.

PMID:
22056989
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway.

Chung S, Leung A, Han BS, Chang MY, Moon JI, Kim CH, Hong S, Pruszak J, Isacson O, Kim KS.

Cell Stem Cell. 2009 Dec 4;5(6):646-58. doi: 10.1016/j.stem.2009.09.015.

PMID:
19951692
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival.

Lee HS, Bae EJ, Yi SH, Shim JW, Jo AY, Kang JS, Yoon EH, Rhee YH, Park CH, Koh HC, Kim HJ, Choi HS, Han JW, Lee YS, Kim J, Li JY, Brundin P, Lee SH.

Stem Cells. 2010 Mar 31;28(3):501-12. doi: 10.1002/stem.294.

PMID:
20049900
[PubMed - indexed for MEDLINE]
Free Article
10.

Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro.

Chung S, Shin BS, Hwang M, Lardaro T, Kang UJ, Isacson O, Kim KS.

Stem Cells. 2006 Jun;24(6):1583-93. Epub 2006 Mar 16.

PMID:
16543488
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The differentiation potential of human foetal neuronal progenitor cells in vitro.

Riaz SS, Theofilopoulos S, Jauniaux E, Stern GM, Bradford HF.

Brain Res Dev Brain Res. 2004 Oct 15;153(1):39-51.

PMID:
15464216
[PubMed - indexed for MEDLINE]
12.

Sonic hedgehog and FGF8: inadequate signals for the differentiation of a dopamine phenotype in mouse and human neurons in culture.

Stull ND, Iacovitti L.

Exp Neurol. 2001 May;169(1):36-43.

PMID:
11312556
[PubMed - indexed for MEDLINE]
13.

Efficient differentiation of mouse embryonic stem cells into motor neurons.

Wu CY, Whye D, Mason RW, Wang W.

J Vis Exp. 2012 Jun 9;(64):e3813. doi: 10.3791/3813.

PMID:
22711008
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells.

Sánchez-Danés A, Consiglio A, Richaud Y, Rodríguez-Pizà I, Dehay B, Edel M, Bové J, Memo M, Vila M, Raya A, Izpisua Belmonte JC.

Hum Gene Ther. 2012 Jan;23(1):56-69. doi: 10.1089/hum.2011.054. Epub 2011 Nov 17.

PMID:
21877920
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nato3 integrates with the Shh-Foxa2 transcriptional network regulating the differentiation of midbrain dopaminergic neurons.

Nissim-Eliraz E, Zisman S, Schatz O, Ben-Arie N.

J Mol Neurosci. 2013 Sep;51(1):13-27. doi: 10.1007/s12031-012-9939-6. Epub 2012 Dec 21.

PMID:
23254923
[PubMed - indexed for MEDLINE]
16.

Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo.

Farkas LM, Dünker N, Roussa E, Unsicker K, Krieglstein K.

J Neurosci. 2003 Jun 15;23(12):5178-86.

PMID:
12832542
[PubMed - indexed for MEDLINE]
Free Article
17.

ES cell-derived renewable and functional midbrain dopaminergic progenitors.

Chung S, Moon JI, Leung A, Aldrich D, Lukianov S, Kitayama Y, Park S, Li Y, Bolshakov VY, Lamonerie T, Kim KS.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9703-8. doi: 10.1073/pnas.1016443108. Epub 2011 May 23.

PMID:
21606375
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation.

Chung S, Shin BS, Hedlund E, Pruszak J, Ferree A, Kang UJ, Isacson O, Kim KS.

J Neurochem. 2006 Jun;97(5):1467-80.

PMID:
16696855
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Differentiation of dopaminergic neurons from human embryonic stem cells: modulation of differentiation by FGF-20.

Shimada H, Yoshimura N, Tsuji A, Kunisada T.

J Biosci Bioeng. 2009 Apr;107(4):447-54. doi: 10.1016/j.jbiosc.2008.12.013.

PMID:
19332307
[PubMed - indexed for MEDLINE]
20.

The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.

Chung S, Hedlund E, Hwang M, Kim DW, Shin BS, Hwang DY, Kang UJ, Isacson O, Kim KS.

Mol Cell Neurosci. 2005 Feb;28(2):241-52.

PMID:
15691706
[PubMed - indexed for MEDLINE]

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