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Results: 1 to 20 of 102

1.

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.

Liew CW, Bochenski J, Kawamori D, Hu J, Leech CA, Wanic K, Malecki M, Warram JH, Qi L, Krolewski AS, Kulkarni RN.

J Clin Invest. 2010 Aug;120(8):2876-88. doi: 10.1172/JCI36849. Epub 2010 Jul 1.

PMID:
20592469
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression.

Bromati CR, Lellis-Santos C, Yamanaka TS, Nogueira TC, Leonelli M, Caperuto LC, Gorjão R, Leite AR, Anhê GF, Bordin S.

Am J Physiol Regul Integr Comp Physiol. 2011 Jan;300(1):R92-100. doi: 10.1152/ajpregu.00169.2010. Epub 2010 Nov 10.

PMID:
21068199
[PubMed - indexed for MEDLINE]
3.

TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4.

Ord D, Meerits K, Ord T.

Exp Cell Res. 2007 Oct 1;313(16):3556-67. Epub 2007 Jul 25.

PMID:
17707795
[PubMed - indexed for MEDLINE]
4.

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.

Du K, Herzig S, Kulkarni RN, Montminy M.

Science. 2003 Jun 6;300(5625):1574-7.

PMID:
12791994
[PubMed - indexed for MEDLINE]
Free Article
5.

Association of TRB3 gene Q84R polymorphism with type 2 diabetes mellitus in Chinese population.

Shi Z, Liu J, Guo Q, Ma X, Shen L, Xu S, Gao H, Yuan X, Zhang J.

Endocrine. 2009 Jun;35(3):414-9. doi: 10.1007/s12020-009-9162-6. Epub 2009 Mar 17.

PMID:
19291425
[PubMed - indexed for MEDLINE]
6.

TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway.

Jousse C, Deval C, Maurin AC, Parry L, Chérasse Y, Chaveroux C, Lefloch R, Lenormand P, Bruhat A, Fafournoux P.

J Biol Chem. 2007 May 25;282(21):15851-61. Epub 2007 Mar 16.

PMID:
17369260
[PubMed - indexed for MEDLINE]
Free Article
7.

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death.

Ohoka N, Yoshii S, Hattori T, Onozaki K, Hayashi H.

EMBO J. 2005 Mar 23;24(6):1243-55. Epub 2005 Mar 10.

PMID:
15775988
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy.

Prudente S, Hribal ML, Flex E, Turchi F, Morini E, De Cosmo S, Bacci S, Tassi V, Cardellini M, Lauro R, Sesti G, Dallapiccola B, Trischitta V.

Diabetes. 2005 Sep;54(9):2807-11.

PMID:
16123373
[PubMed - indexed for MEDLINE]
Free Article
9.

Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells.

Humphrey RK, Newcomb CJ, Yu SM, Hao E, Yu D, Krajewski S, Du K, Jhala US.

J Biol Chem. 2010 Jul 16;285(29):22426-36. doi: 10.1074/jbc.M110.123786. Epub 2010 Apr 26.

PMID:
20421299
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Roles and regulation of the transcription factor CREB in pancreatic β -cells.

Dalle S, Quoyer J, Varin E, Costes S.

Curr Mol Pharmacol. 2011 Nov;4(3):187-95. Review.

PMID:
21488836
[PubMed - indexed for MEDLINE]
11.

The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion.

Dai FF, Zhang Y, Kang Y, Wang Q, Gaisano HY, Braunewell KH, Chan CB, Wheeler MB.

J Biol Chem. 2006 Aug 4;281(31):21942-53. Epub 2006 May 26.

PMID:
16731532
[PubMed - indexed for MEDLINE]
Free Article
12.

Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation.

He L, Simmen FA, Mehendale HM, Ronis MJ, Badger TM.

J Biol Chem. 2006 Apr 21;281(16):11126-34. Epub 2006 Feb 1.

PMID:
16452480
[PubMed - indexed for MEDLINE]
Free Article
13.

Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.

Marinho R, Ropelle ER, Cintra DE, De Souza CT, Da Silva AS, Bertoli FC, Colantonio E, D'Almeida V, Pauli JR.

J Cell Physiol. 2012 Jul;227(7):2917-26. doi: 10.1002/jcp.23037.

PMID:
21938726
[PubMed - indexed for MEDLINE]
14.

TRB3 mediates homocysteine-induced inhibition of endothelial cell proliferation.

Zou T, Liu WJ, Li SD, Zhou W, Yang JF, Zou CG.

J Cell Physiol. 2011 Nov;226(11):2782-9. doi: 10.1002/jcp.22554.

PMID:
21935927
[PubMed - indexed for MEDLINE]
15.

The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases.

Prudente S, Sesti G, Pandolfi A, Andreozzi F, Consoli A, Trischitta V.

Endocr Rev. 2012 Aug;33(4):526-46. doi: 10.1210/er.2011-1042. Epub 2012 May 10. Review.

PMID:
22577090
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.

Bernal-Mizrachi E, Fatrai S, Johnson JD, Ohsugi M, Otani K, Han Z, Polonsky KS, Permutt MA.

J Clin Invest. 2004 Oct;114(7):928-36.

PMID:
15467831
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

TRB3, upregulated by ox-LDL, mediates human monocyte-derived macrophage apoptosis.

Shang YY, Wang ZH, Zhang LP, Zhong M, Zhang Y, Deng JT, Zhang W.

FEBS J. 2009 May;276(10):2752-61. doi: 10.1111/j.1742-4658.2009.06998.x. Epub 2009 Apr 6.

PMID:
19389115
[PubMed - indexed for MEDLINE]
18.

Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

Diabetes. 2008 May;57(5):1195-204. doi: 10.2337/db07-1469. Epub 2008 Feb 14.

PMID:
18276765
[PubMed - indexed for MEDLINE]
Free Article
19.

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.

Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE.

Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23.

PMID:
19549714
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

Wang H, Gambosova K, Cooper ZA, Holloway MP, Kassai A, Izquierdo D, Cleveland K, Boney CM, Altura RA.

BMC Mol Biol. 2010 Aug 31;11:66. doi: 10.1186/1471-2199-11-66.

PMID:
20807437
[PubMed - indexed for MEDLINE]
Free PMC Article

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