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Recombinant antibodies specific for the Plasmodium falciparum histidine-rich protein 2.

Ravaoarisoa E, Zamanka H, Fusai T, Bellalou J, Bedouelle H, Mercereau-Puijalon O, Fandeur T.

MAbs. 2010 Jul-Aug;2(4):416-27. Epub 2010 Jul 1.


Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2.

Leow CH, Jones M, Cheng Q, Mahler S, McCarthy J.

Malar J. 2014 Jul 18;13:277. doi: 10.1186/1475-2875-13-277.


Novel monoclonal antibody against truncated C terminal region of Histidine Rich Protein2 (PfHRP2) and its utility for the specific diagnosis of malaria caused by Plasmodium falciparum.

Verma R, Jayaprakash NS, Vijayalakshmi MA, Venkataraman K.

Exp Parasitol. 2015 Mar;150:56-66. doi: 10.1016/j.exppara.2015.01.001. Epub 2015 Jan 12.


Circulating antibodies against Plasmodium falciparum histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests.

Ho MF, Baker J, Lee N, Luchavez J, Ariey F, Nhem S, Oyibo W, Bell D, González I, Chiodini P, Gatton ML, Cheng Q, McCarthy JS.

Malar J. 2014 Dec 6;13:480. doi: 10.1186/1475-2875-13-480.


New developments in malaria diagnostics: monoclonal antibodies against Plasmodium dihydrofolate reductase-thymidylate synthase, heme detoxification protein and glutamate rich protein.

Kattenberg JH, Versteeg I, Migchelsen SJ, González IJ, Perkins MD, Mens PF, Schallig HD.

MAbs. 2012 Jan-Feb;4(1):120-6. doi: 10.4161/mabs.4.1.18529.


Identification of optimal epitopes for Plasmodium falciparum rapid diagnostic tests that target histidine-rich proteins 2 and 3.

Lee N, Gatton ML, Pelecanos A, Bubb M, Gonzalez I, Bell D, Cheng Q, McCarthy JS.

J Clin Microbiol. 2012 Apr;50(4):1397-405. doi: 10.1128/JCM.06533-11. Epub 2012 Jan 18.


Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests.

Baker J, McCarthy J, Gatton M, Kyle DE, Belizario V, Luchavez J, Bell D, Cheng Q.

J Infect Dis. 2005 Sep 1;192(5):870-7. Epub 2005 Jul 21.


Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests.

Baker J, Ho MF, Pelecanos A, Gatton M, Chen N, Abdullah S, Albertini A, Ariey F, Barnwell J, Bell D, Cunningham J, Djalle D, Echeverry DF, Gamboa D, Hii J, Kyaw MP, Luchavez J, Membi C, Menard D, Murillo C, Nhem S, Ogutu B, Onyor P, Oyibo W, Wang SQ, McCarthy J, Cheng Q.

Malar J. 2010 May 17;9:129. doi: 10.1186/1475-2875-9-129.


Adjuvant poly(N-isopropylacrylamide) generates more efficient monoclonal antibodies against truncated recombinant histidine-rich protein2 of Plasmodium falciparum for malaria diagnosis.

Verma R, Ravichandran R, Jayaprakash NS, Kumar A, Vijayalakshmi MA, Venkataraman K.

Biotechnol J. 2015 May;10(5):772-82. doi: 10.1002/biot.201400386. Epub 2015 Feb 11.


Monoclonal antibodies against recombinant histidine-rich protein 2 of Plasmodium falciparum and their use in malaria diagnosis.

Merwyn S, Gopalan N, Singh AK, Rai GP, Agarwal GS.

Hybridoma (Larchmt). 2011 Dec;30(6):519-24. doi: 10.1089/hyb.2011.0061.


Accuracy of PfHRP2 versus Pf-pLDH antigen detection by malaria rapid diagnostic tests in hospitalized children in a seasonal hyperendemic malaria transmission area in Burkina Faso.

Maltha J, Guiraud I, Lompo P, Kaboré B, Gillet P, Van Geet C, Tinto H, Jacobs J.

Malar J. 2014 Jan 13;13:20. doi: 10.1186/1475-2875-13-20.


High performance of histidine-rich protein 2 based rapid diagnostic tests in French Guiana are explained by the absence of pfhrp2 gene deletion in P. falciparum.

Trouvay M, Palazon G, Berger F, Volney B, Blanchet D, Faway E, Donato D, Legrand E, Carme B, Musset L.

PLoS One. 2013 Sep 23;8(9):e74269. doi: 10.1371/journal.pone.0074269. eCollection 2013.


Development of diagnostic reagents: raising antibodies against synthetic peptides of PfHRP-2 and LDH using microsphere delivery.

Tomar D, Biswas S, Tripathi V, Rao DN.

Immunobiology. 2006;211(10):797-805. Epub 2006 Jul 7.


Evaluation of a PfHRP2 and a pLDH-based rapid diagnostic test for the diagnosis of severe malaria in 2 populations of African children.

Hendriksen IC, Mtove G, Pedro AJ, Gomes E, Silamut K, Lee SJ, Mwambuli A, Gesase S, Reyburn H, Day NP, White NJ, von Seidlein L, Dondorp AM.

Clin Infect Dis. 2011 May;52(9):1100-7. doi: 10.1093/cid/cir143.


Dried Plasmodium falciparum-infected samples as positive controls for malaria rapid diagnostic tests.

Aidoo M, Patel JC, Barnwell JW.

Malar J. 2012 Jul 23;11:239. doi: 10.1186/1475-2875-11-239.


Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals.

Nguyen TV, Sacci JB Jr, de la Vega P, John CC, James AA, Kang AS.

Malar J. 2009 Oct 23;8:235. doi: 10.1186/1475-2875-8-235.


Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries.

Abba K, Deeks JJ, Olliaro P, Naing CM, Jackson SM, Takwoingi Y, Donegan S, Garner P.

Cochrane Database Syst Rev. 2011 Jul 6;(7):CD008122. doi: 10.1002/14651858.CD008122.pub2. Review.

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