Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 237

Similar articles for PubMed (Select 20580554)

1.

Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

Chang W, Du J, Rachakonda S, Ross BS, Convers-Reignier S, Yau WT, Pons JF, Murakami E, Bao H, Steuer HM, Furman PA, Otto MJ, Sofia MJ.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4539-43. doi: 10.1016/j.bmcl.2010.06.025. Epub 2010 Jun 8.

PMID:
20580554
2.

Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.

Mish MR, Cho A, Kirschberg T, Xu J, Zonte CS, Fenaux M, Park Y, Babusis D, Feng JY, Ray AS, Kim CU.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3092-5. doi: 10.1016/j.bmcl.2014.05.015. Epub 2014 May 22.

PMID:
24907145
3.

Nucleoside analog inhibitors of hepatitis C virus replication.

Carroll SS, Olsen DB.

Infect Disord Drug Targets. 2006 Mar;6(1):17-29. Review.

PMID:
16787301
4.

Synthesis and anti-HCV activity of a new 2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogue.

Hu W, Wang P, Song C, Pan Z, Wang Q, Guo X, Yu X, Shen Z, Wang S, Chang J.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7297-8. doi: 10.1016/j.bmcl.2010.10.076. Epub 2010 Nov 4.

PMID:
21106452
5.

Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides.

Cho A, Saunders OL, Butler T, Zhang L, Xu J, Vela JE, Feng JY, Ray AS, Kim CU.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2705-7. doi: 10.1016/j.bmcl.2012.02.105. Epub 2012 Mar 8.

PMID:
22446091
6.

Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.

Di Francesco ME, Avolio S, Pompei M, Pesci S, Monteagudo E, Pucci V, Giuliano C, Fiore F, Rowley M, Summa V.

Bioorg Med Chem. 2012 Aug 1;20(15):4801-11. doi: 10.1016/j.bmc.2012.05.067. Epub 2012 Jun 6.

PMID:
22770556
7.

3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of hepatitis C virus subgenomic replicon and NS5B polymerase activity.

Priet S, Zlatev I, Barvik I, Geerts K, Leyssen P, Neyts J, Dutartre H, Canard B, Vasseur JJ, Morvan F, Alvarez K.

J Med Chem. 2010 Sep 23;53(18):6608-17. doi: 10.1021/jm100102v. Erratum in: J Med Chem. 2011 Jul 14;54(13):4936.

PMID:
20799693
8.

Inhibitors of the HCV NS5B polymerase: new hope for the treatment of hepatitis C infections.

Beaulieu PL, Tsantrizos YS.

Curr Opin Investig Drugs. 2004 Aug;5(8):838-50. Review.

PMID:
15600240
9.

Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.

Beaulieu PL, Bousquet Y, Gauthier J, Gillard J, Marquis M, McKercher G, Pellerin C, Valois S, Kukolj G.

J Med Chem. 2004 Dec 30;47(27):6884-92.

PMID:
15615537
10.

Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.

Rondla R, Coats SJ, McBrayer TR, Grier J, Johns M, Tharnish PM, Whitaker T, Zhou L, Schinazi RF.

Antivir Chem Chemother. 2009 Oct 19;20(2):99-106. doi: 10.3851/1400.

PMID:
19843980
11.

Synthesis and antiviral properties of novel tetracyclic nucleoside inhibitors of hepatitis C NS5B polymerase.

Di Francesco ME, Avolio S, Dessole G, Koch U, Pompei M, Pucci V, Rowley M, Summa V.

Nucleosides Nucleotides Nucleic Acids. 2012;31(8):592-607. doi: 10.1080/15257770.2012.707344.

PMID:
22908950
12.

Nucleoside analog inhibitors of hepatitis C viral replication: recent advances, challenges and trends.

Furman PA, Lam AM, Murakami E.

Future Med Chem. 2009 Nov;1(8):1429-52. doi: 10.4155/fmc.09.88. Review.

PMID:
21426058
13.

Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase.

Kukolj G, McGibbon GA, McKercher G, Marquis M, Lefèbvre S, Thauvette L, Gauthier J, Goulet S, Poupart MA, Beaulieu PL.

J Biol Chem. 2005 Nov 25;280(47):39260-7. Epub 2005 Sep 27.

14.

Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.

Madela K, McGuigan C.

Future Med Chem. 2012 Apr;4(5):625-50. doi: 10.4155/fmc.12.10. Review.

PMID:
22458682
15.

Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors.

Hendricks RT, Fell JB, Blake JF, Fischer JP, Robinson JE, Spencer SR, Stengel PJ, Bernacki AL, Leveque VJ, Le Pogam S, Rajyaguru S, Najera I, Josey JA, Harris JR, Swallow S.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3637-41. doi: 10.1016/j.bmcl.2009.04.119. Epub 2009 May 3.

PMID:
19447623
16.

Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors.

Stammers TA, Coulombe R, Rancourt J, Thavonekham B, Fazal G, Goulet S, Jakalian A, Wernic D, Tsantrizos Y, Poupart MA, Bös M, McKercher G, Thauvette L, Kukolj G, Beaulieu PL.

Bioorg Med Chem Lett. 2013 May 1;23(9):2585-9. doi: 10.1016/j.bmcl.2013.02.110. Epub 2013 Mar 7.

PMID:
23545108
17.

The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture.

Klumpp K, Lévêque V, Le Pogam S, Ma H, Jiang WR, Kang H, Granycome C, Singer M, Laxton C, Hang JQ, Sarma K, Smith DB, Heindl D, Hobbs CJ, Merrett JH, Symons J, Cammack N, Martin JA, Devos R, Nájera I.

J Biol Chem. 2006 Feb 17;281(7):3793-9. Epub 2005 Nov 29.

18.

2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.

Pacini B, Avolio S, Ercolani C, Koch U, Migliaccio G, Narjes F, Pacini L, Tomei L, Harper S.

Bioorg Med Chem Lett. 2009 Nov 1;19(21):6245-9. doi: 10.1016/j.bmcl.2009.06.106. Epub 2009 Jul 17.

PMID:
19800789
19.

A 2'-deoxy-2'-fluoro-2'-C-methyl uridine cyclopentyl carbocyclic analog and its phosphoramidate prodrug as inhibitors of HCV NS5B polymerase.

Liu J, Du J, Wang P, Nagarathnam D, Espiritu CL, Bao H, Murakami E, Furman PA, Sofia MJ.

Nucleosides Nucleotides Nucleic Acids. 2012 Apr;31(4):277-85. doi: 10.1080/15257770.2012.658131.

PMID:
22444190
20.

Quinolones as HCV NS5B polymerase inhibitors.

Kumar DV, Rai R, Brameld KA, Somoza JR, Rajagopalan R, Janc JW, Xia YM, Ton TL, Shaghafi MB, Hu H, Lehoux I, To N, Young WB, Green MJ.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):82-7. doi: 10.1016/j.bmcl.2010.11.068. Epub 2010 Nov 21.

PMID:
21145235
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk