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Items: 1 to 20 of 125

1.

An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.

Blom T, Bergelin N, Meinander A, Löf C, Slotte JP, Eriksson JE, Törnquist K.

BMC Cell Biol. 2010 Jun 24;11:45. doi: 10.1186/1471-2121-11-45.

2.

Sphingosine-1-phosphate signaling in physiology and diseases.

Takuwa Y, Okamoto Y, Yoshioka K, Takuwa N.

Biofactors. 2012 Sep-Oct;38(5):329-37. doi: 10.1002/biof.1030. Epub 2012 Jun 7. Review.

PMID:
22674845
3.

Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.

Arikawa K, Takuwa N, Yamaguchi H, Sugimoto N, Kitayama J, Nagawa H, Takehara K, Takuwa Y.

J Biol Chem. 2003 Aug 29;278(35):32841-51. Epub 2003 Jun 16.

4.

Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

Schnitzer SE, Weigert A, Zhou J, Brüne B.

Mol Cancer Res. 2009 Mar;7(3):393-401. doi: 10.1158/1541-7786.MCR-08-0156. Epub 2009 Feb 24.

5.

S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition.

Liu W, Lan T, Xie X, Huang K, Peng J, Huang J, Shen X, Liu P, Huang H.

Exp Cell Res. 2012 May 1;318(8):936-43. doi: 10.1016/j.yexcr.2012.02.020. Epub 2012 Mar 1.

PMID:
22406263
6.

Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.

Dueñas AI, Aceves M, Fernández-Pisonero I, Gómez C, Orduña A, Crespo MS, García-Rodríguez C.

Cardiovasc Res. 2008 Aug 1;79(3):537-44. doi: 10.1093/cvr/cvn087. Epub 2008 Apr 14.

7.

Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells.

Zhang W, An J, Jawadi H, Siow DL, Lee JF, Zhao J, Gartung A, Maddipati KR, Honn KV, Wattenberg BW, Lee MJ.

Prostaglandins Other Lipid Mediat. 2013 Oct;106:62-71. doi: 10.1016/j.prostaglandins.2013.06.001. Epub 2013 Jun 11.

9.

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M, Takata S, Kaneko S, Takuwa Y.

Cardiovasc Res. 2008 Sep 1;79(4):689-97. doi: 10.1093/cvr/cvn118. Epub 2008 May 14.

10.

Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells.

Long JS, Fujiwara Y, Edwards J, Tannahill CL, Tigyi G, Pyne S, Pyne NJ.

J Biol Chem. 2010 Nov 12;285(46):35957-66. doi: 10.1074/jbc.M110.117945. Epub 2010 Sep 13.

11.

Sphingosine 1-phosphate regulates myogenic differentiation: a major role for S1P2 receptor.

Donati C, Meacci E, Nuti F, Becciolini L, Farnararo M, Bruni P.

FASEB J. 2005 Mar;19(3):449-51. Epub 2004 Dec 29.

12.

Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor.

Walter DH, Rochwalsky U, Reinhold J, Seeger F, Aicher A, Urbich C, Spyridopoulos I, Chun J, Brinkmann V, Keul P, Levkau B, Zeiher AM, Dimmeler S, Haendeler J.

Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):275-82. Epub 2006 Dec 7.

13.

S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.

Chang CL, Ho MC, Lee PH, Hsu CY, Huang WP, Lee H.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C451-8. doi: 10.1152/ajpcell.00586.2008. Epub 2009 May 27.

14.
15.

Aberrant Gi protein coupled receptor-mediated cell survival signaling in rheumatoid arthritis B cell lines.

Tan SY, Xiao L, Pi X, Holoshitz J.

Front Biosci. 2007 Jan 1;12:1651-60.

PMID:
17127411
16.

Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts.

Donati C, Cencetti F, Nincheri P, Bernacchioni C, Brunelli S, Clementi E, Cossu G, Bruni P.

Stem Cells. 2007 Jul;25(7):1713-9. Epub 2007 Apr 26.

18.

Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells.

Takeya H, Gabazza EC, Aoki S, Ueno H, Suzuki K.

Blood. 2003 Sep 1;102(5):1693-700. Epub 2003 May 1.

19.

TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes.

Osawa Y, Banno Y, Nagaki M, Brenner DA, Naiki T, Nozawa Y, Nakashima S, Moriwaki H.

J Immunol. 2001 Jul 1;167(1):173-80.

20.

Sphingosine 1-phosphate inhibits migration and RANTES production in human bronchial smooth muscle cells.

Kawata T, Ishizuka T, Tomura H, Hisada T, Dobashi K, Tsukagoshi H, Ishiwara M, Kurose H, Mori M, Okajima F.

Biochem Biophys Res Commun. 2005 Jun 3;331(2):640-7.

PMID:
15850807
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