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Items: 1 to 20 of 176

1.

Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function.

Robert-Cooperman CE, Carnegie JR, Wilson CG, Yang J, Cook JR, Wu J, Young RA, Wolf BA, Burkhardt BR.

Diabetes. 2010 Sep;59(9):2209-18. doi: 10.2337/db09-1552. Epub 2010 Jun 21. Erratum in: Diabetes. 2010 Dec;59(12):3257.

2.

Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells.

Yang J, Robert CE, Burkhardt BR, Young RA, Wu J, Gao Z, Wolf BA.

Diabetes. 2005 Nov;54(11):3217-28.

3.

PANDER transgenic mice display fasting hyperglycemia and hepatic insulin resistance.

Robert-Cooperman CE, Dougan GC, Moak SL, Athanason MG, Kuehl MN, Bell-Temin H, Stevens SM Jr, Burkhardt BR.

J Endocrinol. 2014 Jan 27;220(3):219-31. doi: 10.1530/JOE-13-0338. Print 2014 Mar.

4.

Enhanced glucose tolerance in pancreatic-derived factor (PANDER) knockout C57BL/6 mice.

Moak SL, Dougan GC, MarElia CB, Danse WA, Fernandez AM, Kuehl MN, Athanason MG, Burkhardt BR.

Dis Model Mech. 2014 Nov;7(11):1307-15. doi: 10.1242/dmm.016402. Epub 2014 Sep 12.

5.

Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in mice.

Wilson CG, Schupp M, Burkhardt BR, Wu J, Young RA, Wolf BA.

Endocrinology. 2010 Nov;151(11):5174-84. doi: 10.1210/en.2010-0379. Epub 2010 Sep 15.

6.

Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter.

Burkhardt BR, Yang MC, Robert CE, Greene SR, McFadden KK, Yang J, Wu J, Gao Z, Wolf BA.

Biochim Biophys Acta. 2005 Sep 25;1730(3):215-25.

PMID:
16102856
7.

Characterization of the expression, localization, and secretion of PANDER in alpha-cells.

Carnegie JR, Robert-Cooperman CE, Wu J, Young RA, Wolf BA, Burkhardt BR.

Mol Cell Endocrinol. 2010 Aug 30;325(1-2):36-45. doi: 10.1016/j.mce.2010.05.008.

8.

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.

Sørensen H, Winzell MS, Brand CL, Fosgerau K, Gelling RW, Nishimura E, Ahren B.

Diabetes. 2006 Dec;55(12):3463-9.

9.

Pancreatic-derived factor (FAM3B), a novel islet cytokine, induces apoptosis of insulin-secreting beta-cells.

Cao X, Gao Z, Robert CE, Greene S, Xu G, Xu W, Bell E, Campbell D, Zhu Y, Young R, Trucco M, Markmann JF, Naji A, Wolf BA.

Diabetes. 2003 Sep;52(9):2296-303.

10.

Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells.

Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y.

Endocrinology. 2008 Feb;149(2):672-80. Epub 2007 Oct 25.

PMID:
17962352
11.

PANDER KO mice on high-fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia.

Robert-Cooperman CE, Wilson CG, Burkhardt BR.

FEBS Lett. 2011 May 6;585(9):1345-9. doi: 10.1016/j.febslet.2011.04.005. Epub 2011 Apr 7.

12.

Effects of overexpression of pancreatic derived factor (FAM3B) in isolated mouse islets and insulin-secreting betaTC3 cells.

Cao X, Yang J, Burkhardt BR, Gao Z, Wong RK, Greene SR, Wu J, Wolf BA.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E543-50. Epub 2005 May 31.

13.

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.

14.

Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic β-cells by MCP-1 (CCL2).

Hou X, Wang O, Li Z, Mou H, Chen J, Deng B, Qian L, Liu X, Le Y.

Mol Cell Endocrinol. 2011 Aug 22;343(1-2):18-24. doi: 10.1016/j.mce.2011.05.039. Epub 2011 Jun 1.

PMID:
21664946
15.

Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.

Bao S, Jacobson DA, Wohltmann M, Bohrer A, Jin W, Philipson LH, Turk J.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E217-29. Epub 2007 Sep 25.

16.

Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells.

Yang J, Gao Z, Robert CE, Burkhardt BR, Gaweska H, Wagner A, Wu J, Greene SR, Young RA, Wolf BA.

Biochemistry. 2005 Aug 30;44(34):11342-52.

PMID:
16114871
17.

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.

da Silva Xavier G, Mondragon A, Sun G, Chen L, McGinty JA, French PM, Rutter GA.

Diabetologia. 2012 Oct;55(10):2667-76. doi: 10.1007/s00125-012-2600-7. Epub 2012 Jun 21.

PMID:
22717537
18.

Hepatic nutrient and hormonal regulation of the PANcreatic-DERived factor (PANDER) promoter.

Ratliff WA, Athanason MG, Chechele AC, Kuehl MN, Fernandez AM, MarElia CB, Burkhardt BR.

Mol Cell Endocrinol. 2015 Sep 15;413:101-12. doi: 10.1016/j.mce.2015.05.040. Epub 2015 Jun 26.

PMID:
26123584
19.

The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo.

Ittner AA, Bertz J, Chan TY, van Eersel J, Polly P, Ittner LM.

Diabetologia. 2014 Jul;57(7):1410-9. doi: 10.1007/s00125-014-3230-z. Epub 2014 Apr 15.

PMID:
24733160
20.

Impaired insulin secretion in vivo but enhanced insulin secretion from isolated islets in pancreatic beta cell-specific vascular endothelial growth factor-A knock-out mice.

Iwashita N, Uchida T, Choi JB, Azuma K, Ogihara T, Ferrara N, Gerber H, Kawamori R, Inoue M, Watada H.

Diabetologia. 2007 Feb;50(2):380-9. Epub 2006 Dec 16.

PMID:
17180351
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