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Human FANCC is hypomorphic in murine Fancc-deficient cells.

Hays LE, Keeble WW, Yates JE, Rathbun RK, Koretsky T, Olson SB, Sun Z, Clapp DW, Bagby GC Jr.

Blood. 2010 Sep 23;116(12):2057-60. doi: 10.1182/blood-2010-02-266411. Epub 2010 Jun 16.


Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis.

Saadatzadeh MR, Bijangi-Vishehsaraei K, Kapur R, Haneline LS.

Blood. 2009 Mar 19;113(12):2655-60. doi: 10.1182/blood-2008-09-181420. Epub 2009 Jan 23.


Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.

Bijangi-Vishehsaraei K, Saadatzadeh MR, Werne A, McKenzie KA, Kapur R, Ichijo H, Haneline LS.

Blood. 2005 Dec 15;106(13):4124-30. Epub 2005 Aug 18.


TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.

Vanderwerf SM, Svahn J, Olson S, Rathbun RK, Harrington C, Yates J, Keeble W, Anderson DC, Anur P, Pereira NF, Pilonetto DV, Pasquini R, Bagby GC.

Blood. 2009 Dec 17;114(26):5290-8. doi: 10.1182/blood-2009-05-222414. Epub 2009 Oct 22.


TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

Li J, Sejas DP, Zhang X, Qiu Y, Nattamai KJ, Rani R, Rathbun KR, Geiger H, Williams DA, Bagby GC, Pang Q.

J Clin Invest. 2007 Nov;117(11):3283-95.


Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells.

Si Y, Pulliam AC, Linka Y, Ciccone S, Leurs C, Yuan J, Eckermann O, Fruehauf S, Mooney S, Hanenberg H, Clapp DW.

Blood. 2008 Dec 1;112(12):4458-65. doi: 10.1182/blood-2007-07-102947. Epub 2008 Aug 6.


p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes.

Anur P, Yates J, Garbati MR, Vanderwerf S, Keeble W, Rathbun K, Hays LE, Tyner JW, Svahn J, Cappelli E, Dufour C, Bagby GC.

Blood. 2012 Mar 1;119(9):1992-2002. doi: 10.1182/blood-2011-06-354647. Epub 2012 Jan 10.


Phenotypic correction of Fanconi anemia group C knockout mice.

Gush KA, Fu KL, Grompe M, Walsh CE.

Blood. 2000 Jan 15;95(2):700-4.


The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality.

Pang Q, Christianson TA, Keeble W, Diaz J, Faulkner GR, Reifsteck C, Olson S, Bagby GC.

Blood. 2001 Sep 1;98(5):1392-401.


The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors.

Pang Q, Fagerlie S, Christianson TA, Keeble W, Faulkner G, Diaz J, Rathbun RK, Bagby GC.

Mol Cell Biol. 2000 Jul;20(13):4724-35.


Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking.

Phelps RA, Gingras H, Hockenbery DM.

Exp Cell Res. 2007 Jul 1;313(11):2283-92. Epub 2007 Apr 6.


A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.

Freie BW, Ciccone SL, Li X, Plett PA, Orschell CM, Srour EF, Hanenberg H, Schindler D, Lee SH, Clapp DW.

J Biol Chem. 2004 Dec 3;279(49):50986-93. Epub 2004 Sep 17.


Hematopoietic stem cells from fancc(-/-) mice have lower growth and differentiation potential in response to growth factors.

Aubé M, Lafrance M, Charbonneau C, Goulet I, Carreau M.

Stem Cells. 2002;20(5):438-47.


In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.

van der Heijden MS, Brody JR, Dezentje DA, Gallmeier E, Cunningham SC, Swartz MJ, DeMarzo AM, Offerhaus GJ, Isacoff WH, Hruban RH, Kern SE.

Clin Cancer Res. 2005 Oct 15;11(20):7508-15.


Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution.

Haneline LS, Li X, Ciccone SL, Hong P, Yang Y, Broxmeyer HE, Lee SH, Orazi A, Srour EF, Clapp DW.

Blood. 2003 Feb 15;101(4):1299-307. Epub 2002 Oct 10.


Loss of FancC function results in decreased hematopoietic stem cell repopulating ability.

Haneline LS, Gobbett TA, Ramani R, Carreau M, Buchwald M, Yoder MC, Clapp DW.

Blood. 1999 Jul 1;94(1):1-8.


Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.

Kamimae-Lanning AN, Goloviznina NA, Kurre P.

Blood. 2013 Mar 14;121(11):2008-12. doi: 10.1182/blood-2012-06-439679. Epub 2013 Jan 11.

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