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Results: 1 to 20 of 516

1.

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Saika S, Hara T, Nomura M, Yoshimura A.

J Immunol. 2010 Jul 15;185(2):842-55. doi: 10.4049/jimmunol.0904100. Epub 2010 Jun 14. Erratum in: J Immunol. 2011 Jan 1;186(1):632. Shizuya, Saika [corrected to Saika, Shizuya].

PMID:
20548029
[PubMed - indexed for MEDLINE]
Free Article
2.

SMAD2 is essential for TGF beta-mediated Th17 cell generation.

Malhotra N, Robertson E, Kang J.

J Biol Chem. 2010 Sep 17;285(38):29044-8. doi: 10.1074/jbc.C110.156745. Epub 2010 Jul 23.

PMID:
20656683
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

TGF-β function in immune suppression.

Yoshimura A, Muto G.

Curr Top Microbiol Immunol. 2011;350:127-47. doi: 10.1007/82_2010_87. Review.

PMID:
20680806
[PubMed - indexed for MEDLINE]
4.

IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction.

Prochazkova J, Pokorna K, Holan V.

Immunobiology. 2012 Jan;217(1):74-82. doi: 10.1016/j.imbio.2011.07.032. Epub 2011 Aug 5.

PMID:
21903294
[PubMed - indexed for MEDLINE]
5.

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

Zhu J, Davidson TS, Wei G, Jankovic D, Cui K, Schones DE, Guo L, Zhao K, Shevach EM, Paul WE.

J Exp Med. 2009 Feb 16;206(2):329-41. doi: 10.1084/jem.20081666. Epub 2009 Feb 2.

PMID:
19188499
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways.

Sugiyama Y, Kakoi K, Kimura A, Takada I, Kashiwagi I, Wakabayashi Y, Morita R, Nomura M, Yoshimura A.

Int Immunol. 2012 Apr;24(4):253-65. doi: 10.1093/intimm/dxr126. Epub 2012 Feb 13.

PMID:
22331441
[PubMed - indexed for MEDLINE]
Free Article
7.

Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells.

Lu L, Wang J, Zhang F, Chai Y, Brand D, Wang X, Horwitz DA, Shi W, Zheng SG.

J Immunol. 2010 Apr 15;184(8):4295-306. doi: 10.4049/jimmunol.0903418. Epub 2010 Mar 19.

PMID:
20304828
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway.

Grainger JR, Smith KA, Hewitson JP, McSorley HJ, Harcus Y, Filbey KJ, Finney CA, Greenwood EJ, Knox DP, Wilson MS, Belkaid Y, Rudensky AY, Maizels RM.

J Exp Med. 2010 Oct 25;207(11):2331-41. doi: 10.1084/jem.20101074. Epub 2010 Sep 27.

PMID:
20876311
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

TGF-beta-exposed plasmacytoid dendritic cells participate in Th17 commitment.

Bonnefoy F, Couturier M, Clauzon A, Rémy-Martin JP, Gaugler B, Tiberghien P, Chen W, Saas P, Perruche S.

J Immunol. 2011 Jun 1;186(11):6157-64. doi: 10.4049/jimmunol.1002497. Epub 2011 Apr 25.

PMID:
21518970
[PubMed - indexed for MEDLINE]
Free Article
10.

Histone 3 lysine 9 (H3K9) methyltransferase recruitment to the interleukin-2 (IL-2) promoter is a mechanism of suppression of IL-2 transcription by the transforming growth factor-β-Smad pathway.

Wakabayashi Y, Tamiya T, Takada I, Fukaya T, Sugiyama Y, Inoue N, Kimura A, Morita R, Kashiwagi I, Takimoto T, Nomura M, Yoshimura A.

J Biol Chem. 2011 Oct 14;286(41):35456-65. doi: 10.1074/jbc.M111.236794. Epub 2011 Aug 23.

PMID:
21862595
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential regulation of Foxp3 and IL-17 expression in CD4 T helper cells by IRAK-1.

Maitra U, Davis S, Reilly CM, Li L.

J Immunol. 2009 May 1;182(9):5763-9. doi: 10.4049/jimmunol.0900124.

PMID:
19380824
[PubMed - indexed for MEDLINE]
Free Article
12.

A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.

Brown KA, Pietenpol JA, Moses HL.

J Cell Biochem. 2007 May 1;101(1):9-33. Review.

PMID:
17340614
[PubMed - indexed for MEDLINE]
13.

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.

Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G, Torisu T, Hanada T, Yasukawa H, Fukuyama S, Inoue H, Nakanishi Y, Kobayashi T, Yoshimura A.

J Immunol. 2008 Mar 15;180(6):3746-56.

PMID:
18322180
[PubMed - indexed for MEDLINE]
Free Article
14.

CD8+ T regulatory cells use a novel genetic program that includes CD103 to suppress Th1 immunity in eye-derived tolerance.

Keino H, Masli S, Sasaki S, Streilein JW, Stein-Streilein J.

Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1533-42.

PMID:
16565389
[PubMed - indexed for MEDLINE]
Free Article
15.

Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation.

Martinez GJ, Zhang Z, Chung Y, Reynolds JM, Lin X, Jetten AM, Feng XH, Dong C.

J Biol Chem. 2009 Dec 18;284(51):35283-6. doi: 10.1074/jbc.C109.078238. Epub .

PMID:
19887374
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Antigen-presenting cell production of IL-10 inhibits T-helper 1 and 17 cell responses and suppresses colitis in mice.

Liu B, Tonkonogy SL, Sartor RB.

Gastroenterology. 2011 Aug;141(2):653-62, 662.e1-4. doi: 10.1053/j.gastro.2011.04.053. Epub 2011 Apr 30.

PMID:
21679711
[PubMed - indexed for MEDLINE]
17.

Transforming growth factor-beta- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis.

Rosendahl A, Speletas M, Leandersson K, Ivars F, Sideras P.

Int Immunol. 2003 Dec;15(12):1401-14.

PMID:
14645149
[PubMed - indexed for MEDLINE]
Free Article
18.

The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression.

Jana S, Jailwala P, Haribhai D, Waukau J, Glisic S, Grossman W, Mishra M, Wen R, Wang D, Williams CB, Ghosh S.

Eur J Immunol. 2009 Sep;39(9):2571-83. doi: 10.1002/eji.200939201.

PMID:
19701891
[PubMed - indexed for MEDLINE]
19.

Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.

Matsuzaki K, Kitano C, Murata M, Sekimoto G, Yoshida K, Uemura Y, Seki T, Taketani S, Fujisawa J, Okazaki K.

Cancer Res. 2009 Jul 1;69(13):5321-30. doi: 10.1158/0008-5472.CAN-08-4203. Epub 2009 Jun 16.

PMID:
19531654
[PubMed - indexed for MEDLINE]
Free Article
20.

Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.

Kaminski S, Hermann-Kleiter N, Meisel M, Thuille N, Cronin S, Hara H, Fresser F, Penninger JM, Baier G.

J Autoimmun. 2011 Nov;37(3):198-208. doi: 10.1016/j.jaut.2011.05.018. Epub 2011 Jun 22.

PMID:
21700422
[PubMed - indexed for MEDLINE]

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