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Items: 1 to 20 of 274

1.

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.

Suvrathan A, Hoeffer CA, Wong H, Klann E, Chattarji S.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11591-6. doi: 10.1073/pnas.1002262107. Epub 2010 Jun 7.

2.

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.

Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. Epub 2007 Sep 19.

3.

Fragile X syndrome and the amygdala.

Suvrathan A, Chattarji S.

Curr Opin Neurobiol. 2011 Jun;21(3):509-15. doi: 10.1016/j.conb.2011.04.005. Review.

PMID:
21555214
4.

Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.

Costa L, Spatuzza M, D'Antoni S, Bonaccorso CM, Trovato C, Musumeci SA, Leopoldo M, Lacivita E, Catania MV, Ciranna L.

Biol Psychiatry. 2012 Dec 1;72(11):924-33. doi: 10.1016/j.biopsych.2012.06.008. Epub 2012 Jul 18.

PMID:
22817866
6.

Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models.

Zhang J, Hou L, Klann E, Nelson DL.

J Neurophysiol. 2009 May;101(5):2572-80. doi: 10.1152/jn.90558.2008. Epub 2009 Feb 25.

7.
8.

Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse.

Gocel J, Larson J.

Neuroscience. 2012 Sep 27;221:170-81. doi: 10.1016/j.neuroscience.2012.06.052. Epub 2012 Jun 28.

9.

Dysregulation of mTOR signaling in fragile X syndrome.

Sharma A, Hoeffer CA, Takayasu Y, Miyawaki T, McBride SM, Klann E, Zukin RS.

J Neurosci. 2010 Jan 13;30(2):694-702. doi: 10.1523/JNEUROSCI.3696-09.2010.

10.

Altered structural and functional synaptic plasticity with motor skill learning in a mouse model of fragile X syndrome.

Padmashri R, Reiner BC, Suresh A, Spartz E, Dunaevsky A.

J Neurosci. 2013 Dec 11;33(50):19715-23. doi: 10.1523/JNEUROSCI.2514-13.2013.

11.

Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.

Zhao MG, Toyoda H, Ko SW, Ding HK, Wu LJ, Zhuo M.

J Neurosci. 2005 Aug 10;25(32):7385-92. Erratum in: J Neurosci. 2005 Aug 31;25(35):8112.

12.

Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice.

Wilson BM, Cox CL.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2454-9. Epub 2007 Feb 7.

13.

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.

Gross C, Nakamoto M, Yao X, Chan CB, Yim SY, Ye K, Warren ST, Bassell GJ.

J Neurosci. 2010 Aug 11;30(32):10624-38. doi: 10.1523/JNEUROSCI.0402-10.2010.

14.

Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome.

Xu ZH, Yang Q, Feng B, Liu SB, Zhang N, Xing JH, Li XQ, Wu YM, Gao GD, Zhao MG.

Mol Neurodegener. 2012 May 28;7:24. doi: 10.1186/1750-1326-7-24.

15.

BDNF in fragile X syndrome.

Castrén ML, Castrén E.

Neuropharmacology. 2014 Jan;76 Pt C:729-36. doi: 10.1016/j.neuropharm.2013.05.018. Epub 2013 May 29. Review.

PMID:
23727436
16.

Abnormal presynaptic short-term plasticity and information processing in a mouse model of fragile X syndrome.

Deng PY, Sojka D, Klyachko VA.

J Neurosci. 2011 Jul 27;31(30):10971-82. doi: 10.1523/JNEUROSCI.2021-11.2011.

17.

Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice.

Pilpel Y, Kolleker A, Berberich S, Ginger M, Frick A, Mientjes E, Oostra BA, Seeburg PH.

J Physiol. 2009 Feb 15;587(Pt 4):787-804. doi: 10.1113/jphysiol.2008.160929. Epub 2008 Dec 22.

18.

Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome.

Zeier Z, Kumar A, Bodhinathan K, Feller JA, Foster TC, Bloom DC.

Gene Ther. 2009 Sep;16(9):1122-9. doi: 10.1038/gt.2009.83. Epub 2009 Jul 2.

19.

Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency.

Li J, Pelletier MR, Perez Velazquez JL, Carlen PL.

Mol Cell Neurosci. 2002 Feb;19(2):138-51.

PMID:
11860268
20.

Deficits in LTP induction by 5-HT2A receptor antagonist in a mouse model for fragile X syndrome.

Xu ZH, Yang Q, Ma L, Liu SB, Chen GS, Wu YM, Li XQ, Liu G, Zhao MG.

PLoS One. 2012;7(10):e48741. doi: 10.1371/journal.pone.0048741. Epub 2012 Oct 31.

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