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Results: 1 to 20 of 150

1.

Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells.

Aronchik I, Bjeldanes LF, Firestone GL.

Cancer Res. 2010 Jun 15;70(12):4961-71. doi: 10.1158/0008-5472.CAN-09-3349. Epub 2010 Jun 8.

PMID:
20530686
[PubMed - indexed for MEDLINE]
Free Article
2.

Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.

Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.

Mol Carcinog. 2012 Nov;51(11):881-94. doi: 10.1002/mc.20857. Epub 2011 Oct 19.

PMID:
22012859
[PubMed - indexed for MEDLINE]
3.

Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.

Leo E, Welsh K, Matsuzawa S, Zapata JM, Kitada S, Mitchell RS, Ely KR, Reed JC.

J Biol Chem. 1999 Aug 6;274(32):22414-22.

PMID:
10428814
[PubMed - indexed for MEDLINE]
Free Article
4.

Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation.

Fotin-Mleczek M, Henkler F, Hausser A, Glauner H, Samel D, Graness A, Scheurich P, Mauri D, Wajant H.

J Biol Chem. 2004 Jan 2;279(1):677-85. Epub 2003 Oct 13.

PMID:
14557256
[PubMed - indexed for MEDLINE]
Free Article
5.

Indole-3-carbinol-induced modulation of NF-kappaB signalling is breast cancer cell-specific and does not correlate with cell death.

Moiseeva EP, Heukers R.

Breast Cancer Res Treat. 2008 Jun;109(3):451-62. Epub 2007 Jul 26.

PMID:
17653853
[PubMed - indexed for MEDLINE]
6.

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing.

Nguyen HH, Aronchik I, Brar GA, Nguyen DH, Bjeldanes LF, Firestone GL.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19750-5. doi: 10.1073/pnas.0806581105. Epub 2008 Dec 8.

PMID:
19064917
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model.

Rahman KM, Sarkar FH, Banerjee S, Wang Z, Liao DJ, Hong X, Sarkar NH.

Mol Cancer Ther. 2006 Nov;5(11):2747-56.

PMID:
17121921
[PubMed - indexed for MEDLINE]
Free Article
8.

CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1.

Mann J, Oakley F, Johnson PW, Mann DA.

J Biol Chem. 2002 May 10;277(19):17125-38. Epub 2002 Mar 8.

PMID:
11886848
[PubMed - indexed for MEDLINE]
Free Article
9.

Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors.

Eliopoulos AG, Stack M, Dawson CW, Kaye KM, Hodgkin L, Sihota S, Rowe M, Young LS.

Oncogene. 1997 Jun 19;14(24):2899-916.

PMID:
9205097
[PubMed - indexed for MEDLINE]
Free Article
10.

TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation.

He L, Grammer AC, Wu X, Lipsky PE.

J Biol Chem. 2004 Dec 31;279(53):55855-65. Epub 2004 Sep 21.

PMID:
15383523
[PubMed - indexed for MEDLINE]
Free Article
11.

Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells.

Rahman KM, Li Y, Sarkar FH.

Nutr Cancer. 2004;48(1):84-94.

PMID:
15203382
[PubMed - indexed for MEDLINE]
12.

Expression of the tumor necrosis factor receptor-associated factors 1 and 2 and regulation of the nuclear factor-kappaB antiapoptotic activity in human gliomas.

Conti A, Ageunnouz M, La Torre D, Cardali S, Angileri FF, Buemi C, Tomasello C, Iacopino DG, D'Avella D, Vita G, Tomasello F.

J Neurosurg. 2005 Nov;103(5):873-81.

PMID:
16304992
[PubMed - indexed for MEDLINE]
13.

Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.

Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF, Firestone GL.

J Biol Chem. 1998 Feb 13;273(7):3838-47.

PMID:
9461564
[PubMed - indexed for MEDLINE]
Free Article
14.

CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells.

Ju JH, Jang K, Lee KM, Kim M, Kim J, Yi JY, Noh DY, Shin I.

Carcinogenesis. 2011 Oct;32(10):1474-83. doi: 10.1093/carcin/bgr173. Epub 2011 Jul 27.

PMID:
21798852
[PubMed - indexed for MEDLINE]
Free Article
15.

CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization.

Pullen SS, Miller HG, Everdeen DS, Dang TT, Crute JJ, Kehry MR.

Biochemistry. 1998 Aug 25;37(34):11836-45.

PMID:
9718306
[PubMed - indexed for MEDLINE]
16.

Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation.

Devergne O, Hatzivassiliou E, Izumi KM, Kaye KM, Kleijnen MF, Kieff E, Mosialos G.

Mol Cell Biol. 1996 Dec;16(12):7098-108.

PMID:
8943365
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways.

Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, Sarkar FH.

Breast Cancer Res Treat. 2011 Feb;126(1):15-25. doi: 10.1007/s10549-010-0883-2. Epub 2010 Apr 9.

PMID:
20379844
[PubMed - indexed for MEDLINE]
18.
19.

Competition between TRAF2 and TRAF6 regulates NF-kappaB activation in human B lymphocytes.

Zhang W, Zhang X, Wu XL, He LS, Zeng XF, Crammer AC, Lipsky PE.

Chin Med Sci J. 2010 Mar;25(1):1-12.

PMID:
20449947
[PubMed - indexed for MEDLINE]
20.

Human RPE expression of cell survival factors.

Yang P, Wiser JL, Peairs JJ, Ebright JN, Zavodni ZJ, Bowes Rickman C, Jaffe GJ.

Invest Ophthalmol Vis Sci. 2005 May;46(5):1755-64.

PMID:
15851579
[PubMed - indexed for MEDLINE]
Free Article

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