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Results: 1 to 20 of 105

1.

Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression.

Kurek KC, Del Mare S, Salah Z, Abdeen S, Sadiq H, Lee SH, Gaudio E, Zanesi N, Jones KB, DeYoung B, Amir G, Gebhardt M, Warman M, Stein GS, Stein JL, Lian JB, Aqeilan RI.

Cancer Res. 2010 Jul 1;70(13):5577-86. doi: 10.1158/0008-5472.CAN-09-4602. Epub 2010 Jun 8.

PMID:
20530675
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Correlation of WWOX, RUNX2 and VEGFA protein expression in human osteosarcoma.

Yang J, Zhao L, Tian W, Liao Z, Zheng H, Wang G, Chen K.

BMC Med Genomics. 2013 Dec 15;6:56. doi: 10.1186/1755-8794-6-56.

PMID:
24330824
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.

Del Mare S, Kurek KC, Stein GS, Lian JB, Aqeilan RI.

Am J Cancer Res. 2011;1(5):585-94. Epub 2011 Apr 3.

PMID:
21731849
[PubMed]
Free PMC Article
4.

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.

van der Deen M, Taipaleenmäki H, Zhang Y, Teplyuk NM, Gupta A, Cinghu S, Shogren K, Maran A, Yaszemski MJ, Ling L, Cool SM, Leong DT, Dierkes C, Zustin J, Salto-Tellez M, Ito Y, Bae SC, Zielenska M, Squire JA, Lian JB, Stein JL, Zambetti GP, Jones SN, Galindo M, Hesse E, Stein GS, van Wijnen AJ.

J Biol Chem. 2013 Jul 19;288(29):21307-19. doi: 10.1074/jbc.M112.445890. Epub 2013 May 29.

PMID:
23720736
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines.

Lucero CM, Vega OA, Osorio MM, Tapia JC, Antonelli M, Stein GS, van Wijnen AJ, Galindo MA.

J Cell Physiol. 2013 Apr;228(4):714-23. doi: 10.1002/jcp.24218.

PMID:
22949168
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma.

Su Y, Wagner ER, Luo Q, Huang J, Chen L, He BC, Zuo GW, Shi Q, Zhang BQ, Zhu G, Bi Y, Luo J, Luo X, Kim SH, Shen J, Rastegar F, Huang E, Gao Y, Gao JL, Yang K, Wietholt C, Li M, Qin J, Haydon RC, He TC, Luu HH.

Oncogene. 2011 Sep 15;30(37):3907-17. doi: 10.1038/onc.2011.97. Epub 2011 Apr 4.

PMID:
21460855
[PubMed - indexed for MEDLINE]
7.

The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.

Aqeilan RI, Hassan MQ, de Bruin A, Hagan JP, Volinia S, Palumbo T, Hussain S, Lee SH, Gaur T, Stein GS, Lian JB, Croce CM.

J Biol Chem. 2008 Aug 1;283(31):21629-39. doi: 10.1074/jbc.M800855200. Epub 2008 May 16.

PMID:
18487609
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma.

Yang J, Cogdell D, Yang D, Hu L, Li H, Zheng H, Du X, Pang Y, Trent J, Chen K, Zhang W.

Cancer Lett. 2010 May 1;291(1):31-8. doi: 10.1016/j.canlet.2009.09.018. Epub 2009 Nov 6.

PMID:
19896763
[PubMed - indexed for MEDLINE]
9.

Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy.

Sadikovic B, Thorner P, Chilton-Macneill S, Martin JW, Cervigne NK, Squire J, Zielenska M.

BMC Cancer. 2010 May 13;10:202. doi: 10.1186/1471-2407-10-202.

PMID:
20465837
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

WW domain containing oxidoreductase induces apoptosis in gallbladder-derived malignant cell by upregulating expression of P73 and PUMA.

Wei D, Zhang X, Zou H, Wang L, Fu B, Wu X, Luo Z, Li X, Ge J, Li Y, Zhu H, Wang K, Wang T, Yang P, Hou Z, Wang W.

Tumour Biol. 2014 Feb;35(2):1539-50. doi: 10.1007/s13277-013-1213-1. Epub 2013 Oct 15.

PMID:
24127039
[PubMed - indexed for MEDLINE]
11.

Functional and clinical characterization of the putative tumor suppressor WWOX in non-small cell lung cancer.

Becker S, Markova B, Wiewrodt R, Hoffarth S, Hähnel PS, Pleiner S, Schmidt LH, Breitenbuecher F, Schuler M.

J Thorac Oncol. 2011 Dec;6(12):1976-83. doi: 10.1097/JTO.0b013e31822e59dd.

PMID:
21892104
[PubMed - indexed for MEDLINE]
12.

WWOX expression in different histologic types and subtypes of non-small cell lung cancer.

Donati V, Fontanini G, Dell'Omodarme M, Prati MC, Nuti S, Lucchi M, Mussi A, Fabbri M, Basolo F, Croce CM, Aqeilan RI.

Clin Cancer Res. 2007 Feb 1;13(3):884-91.

PMID:
17289881
[PubMed - indexed for MEDLINE]
Free Article
13.

WWOX gene expression abolishes ovarian cancer tumorigenicity in vivo and decreases attachment to fibronectin via integrin alpha3.

Gourley C, Paige AJ, Taylor KJ, Ward C, Kuske B, Zhang J, Sun M, Janczar S, Harrison DJ, Muir M, Smyth JF, Gabra H.

Cancer Res. 2009 Jun 1;69(11):4835-42. doi: 10.1158/0008-5472.CAN-08-2974. Epub 2009 May 19.

PMID:
19458077
[PubMed - indexed for MEDLINE]
Free Article
14.

PKD1 negatively regulates cell invasion, migration and proliferation ability of human osteosarcoma.

Onishi Y, Kawamoto T, Kishimoto K, Hara H, Fukase N, Toda M, Harada R, Kurosaka M, Akisue T.

Int J Oncol. 2012 Jun;40(6):1839-48. doi: 10.3892/ijo.2012.1400. Epub 2012 Mar 12.

PMID:
22426824
[PubMed - indexed for MEDLINE]
15.

The role and clinical significance of YES-associated protein 1 in human osteosarcoma.

Zhang YH, Li B, Shen L, Shen Y, Chen XD.

Int J Immunopathol Pharmacol. 2013 Jan-Mar;26(1):157-67.

PMID:
23527718
[PubMed - indexed for MEDLINE]
16.

RUNX2 expression in developing human bones and various bone tumors.

Sugawara M, Kato N, Tsuchiya T, Motoyama T.

Pathol Int. 2011 Oct;61(10):565-71. doi: 10.1111/j.1440-1827.2011.02706.x. Epub 2011 Aug 9.

PMID:
21951664
[PubMed - indexed for MEDLINE]
17.

Alpha-CaMKII plays a critical role in determining the aggressive behavior of human osteosarcoma.

Daft PG, Yuan K, Warram JM, Klein MJ, Siegal GP, Zayzafoon M.

Mol Cancer Res. 2013 Apr;11(4):349-59. doi: 10.1158/1541-7786.MCR-12-0572. Epub 2013 Jan 30.

PMID:
23364534
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

miR-214 promotes the proliferation and invasion of osteosarcoma cells through direct suppression of LZTS1.

Xu Z, Wang T.

Biochem Biophys Res Commun. 2014 Jun 27;449(2):190-5. doi: 10.1016/j.bbrc.2014.04.140. Epub 2014 May 4.

PMID:
24802407
[PubMed - indexed for MEDLINE]
19.

Association of Wwox with ErbB4 in breast cancer.

Aqeilan RI, Donati V, Gaudio E, Nicoloso MS, Sundvall M, Korhonen A, Lundin J, Isola J, Sudol M, Joensuu H, Croce CM, Elenius K.

Cancer Res. 2007 Oct 1;67(19):9330-6.

PMID:
17909041
[PubMed - indexed for MEDLINE]
Free Article
20.

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

Pereira BP, Zhou Y, Gupta A, Leong DT, Aung KZ, Ling L, Pho RW, Galindo M, Salto-Tellez M, Stein GS, Cool SM, van Wijnen AJ, Nathan SS.

J Cell Physiol. 2009 Dec;221(3):778-88. doi: 10.1002/jcp.21921.

PMID:
19746444
[PubMed - indexed for MEDLINE]
Free PMC Article

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