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Items: 1 to 20 of 108

1.

Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is identified as a minimal chondroitin sulfate A-binding region.

Singh K, Gitti RK, Diouf A, Zhou H, Gowda DC, Miura K, Ostazeski SA, Fairhurst RM, Garboczi DN, Long CA.

J Biol Chem. 2010 Aug 6;285(32):24855-62. doi: 10.1074/jbc.M110.118612. Epub 2010 Jun 7.

2.

Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay.

Obiakor H, Avril M, Macdonald NJ, Srinivasan P, Reiter K, Anderson C, Holmes KL, Fried M, Duffy PE, Smith JD, Narum DL, Miller LH.

Clin Vaccine Immunol. 2013 Mar;20(3):433-42. doi: 10.1128/CVI.00638-12. Epub 2013 Jan 23.

3.

VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta.

Rovira-Vallbona E, Monteiro I, Bardají A, Serra-Casas E, Neafsey DE, Quelhas D, Valim C, Alonso P, Dobaño C, Ordi J, Menéndez C, Mayor A.

PLoS One. 2013 Jul 25;8(7):e69753. doi: 10.1371/journal.pone.0069753. Print 2013.

4.

Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.

Singh K, Gittis AG, Nguyen P, Gowda DC, Miller LH, Garboczi DN.

Nat Struct Mol Biol. 2008 Sep;15(9):932-8.

5.

Immunogenicity of Duffy binding-like domains that bind chondroitin sulfate A and protection against pregnancy-associated malaria.

Bir N, Yazdani SS, Avril M, Layez C, Gysin J, Chitnis CE.

Infect Immun. 2006 Oct;74(10):5955-63.

6.

Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites.

Resende M, Ditlev SB, Nielsen MA, Bodevin S, Bruun S, Pinto VV, Clausen H, Turner L, Theander TG, Salanti A, Dahlbäck M.

Int J Parasitol. 2009 Sep;39(11):1195-204. doi: 10.1016/j.ijpara.2009.02.022. Epub 2009 Mar 24.

PMID:
19324047
8.

The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains.

Dahlbäck M, Jørgensen LM, Nielsen MA, Clausen TM, Ditlev SB, Resende M, Pinto VV, Arnot DE, Theander TG, Salanti A.

J Biol Chem. 2011 May 6;286(18):15908-17. doi: 10.1074/jbc.M110.191510. Epub 2011 Mar 11.

9.

Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA.

Andersen P, Nielsen MA, Resende M, Rask TS, Dahlbäck M, Theander T, Lund O, Salanti A.

PLoS Pathog. 2008 Feb 8;4(2):e42. doi: 10.1371/journal.ppat.0040042.

10.

Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies.

Avril M, Gamain B, Lépolard C, Viaud N, Scherf A, Gysin J.

Microbes Infect. 2006 Nov-Dec;8(14-15):2863-71. Epub 2006 Oct 17.

PMID:
17095277
13.

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA.

Resende M, Nielsen MA, Dahlbäck M, Ditlev SB, Andersen P, Sander AF, Ndam NT, Theander TG, Salanti A.

Malar J. 2008 Jun 6;7:104. doi: 10.1186/1475-2875-7-104.

14.

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA.

Srivastava A, Gangnard S, Round A, Dechavanne S, Juillerat A, Raynal B, Faure G, Baron B, Ramboarina S, Singh SK, Belrhali H, England P, Lewit-Bentley A, Scherf A, Bentley GA, Gamain B.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4884-9. doi: 10.1073/pnas.1000951107. Epub 2010 Mar 1.

15.

Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.

Clausen TM, Christoffersen S, Dahlbäck M, Langkilde AE, Jensen KE, Resende M, Agerbæk MØ, Andersen D, Berisha B, Ditlev SB, Pinto VV, Nielsen MA, Theander TG, Larsen S, Salanti A.

J Biol Chem. 2012 Jul 6;287(28):23332-45. doi: 10.1074/jbc.M112.348839. Epub 2012 May 8.

16.

Antibodies to Escherichia coli-expressed C-terminal domains of Plasmodium falciparum variant surface antigen 2-chondroitin sulfate A (VAR2CSA) inhibit binding of CSA-adherent parasites to placental tissue.

Saveria T, Oleinikov AV, Wiliamson K, Chaturvedi R, Lograsso J, Keitany GJ, Fried M, Duffy P.

Infect Immun. 2013 Apr;81(4):1031-9. doi: 10.1128/IAI.00978-12. Epub 2013 Jan 14.

17.

Immunization with recombinant duffy binding-like-gamma3 induces pan-reactive and adhesion-blocking antibodies against placental chondroitin sulfate A-binding Plasmodium falciparum parasites.

Costa FT, Fusaï T, Parzy D, Sterkers Y, Torrentino M, Douki JB, Traoré B, Petres S, Scherf A, Gysin J.

J Infect Dis. 2003 Jul 1;188(1):153-64. Epub 2003 Jun 23.

18.

Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions.

Fernandez P, Petres S, Mécheri S, Gysin J, Scherf A.

PLoS One. 2010 Sep 3;5(9):e12558. doi: 10.1371/journal.pone.0012558.

19.

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.

Dahlbäck M, Rask TS, Andersen PH, Nielsen MA, Ndam NT, Resende M, Turner L, Deloron P, Hviid L, Lund O, Pedersen AG, Theander TG, Salanti A.

PLoS Pathog. 2006 Nov;2(11):e124.

20.
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