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Items: 1 to 20 of 63

1.

CC2D1A, a DM14 and C2 domain protein, activates NF-kappaB through the canonical pathway.

Zhao M, Li XD, Chen Z.

J Biol Chem. 2010 Aug 6;285(32):24372-80. doi: 10.1074/jbc.M109.100057. Epub 2010 Jun 7.

2.

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members.

Trompouki E, Hatzivassiliou E, Tsichritzis T, Farmer H, Ashworth A, Mosialos G.

Nature. 2003 Aug 14;424(6950):793-6.

3.

Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation.

Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, McFerran B, Wyche J, Kolch W, Sedivy JM.

Mol Cell Biol. 2001 Nov;21(21):7207-17.

4.
5.

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.

Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ.

Mol Cell. 2004 May 7;14(3):289-301.

7.

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.

Kovalenko A, Chable-Bessia C, Cantarella G, Israël A, Wallach D, Courtois G.

Nature. 2003 Aug 14;424(6950):801-5.

8.

Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

Jackson-Bernitsas DG, Ichikawa H, Takada Y, Myers JN, Lin XL, Darnay BG, Chaturvedi MM, Aggarwal BB.

Oncogene. 2007 Mar 1;26(10):1385-97. Epub 2006 Sep 4.

PMID:
16953224
9.

Both amino- and carboxyl-terminal domains of TRAF3 negatively regulate NF-kappaB activation induced by OX40 signaling.

Takaori-Kondo A, Hori T, Fukunaga K, Morita R, Kawamata S, Uchiyama T.

Biochem Biophys Res Commun. 2000 Jun 16;272(3):856-63.

PMID:
10860842
10.

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C.

Mol Cell. 2010 Oct 8;40(1):63-74. doi: 10.1016/j.molcel.2010.09.008.

11.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
12.
13.

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.

PMID:
16924232
14.

TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.

Morlon A, Munnich A, Smahi A.

Hum Mol Genet. 2005 Dec 1;14(23):3751-7. Epub 2005 Oct 26.

15.

TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB.

Prickett TD, Ninomiya-Tsuji J, Broglie P, Muratore-Schroeder TL, Shabanowitz J, Hunt DF, Brautigan DL.

J Biol Chem. 2008 Jul 11;283(28):19245-54. doi: 10.1074/jbc.M800943200. Epub 2008 May 2.

16.

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway.

Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, Gaynor RB.

J Mol Biol. 2003 Feb 7;326(1):105-15.

PMID:
12547194
17.

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.

Van Huffel S, Delaei F, Heyninck K, De Valck D, Beyaert R.

J Biol Chem. 2001 Aug 10;276(32):30216-23. Epub 2001 Jun 4.

18.

JNK-binding protein 1 regulates NF-kappaB activation through TRAF2 and TAK1.

Yamaguchi T, Miyashita C, Koyano S, Kanda H, Yoshioka K, Shiba T, Takamatsu N, Ito M.

Cell Biol Int. 2009 Mar;33(3):364-8.

PMID:
19385034
19.
20.

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6.

Mizukami J, Takaesu G, Akatsuka H, Sakurai H, Ninomiya-Tsuji J, Matsumoto K, Sakurai N.

Mol Cell Biol. 2002 Feb;22(4):992-1000.

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