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Results: 1 to 20 of 130

1.

Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.

Geraldo RB, Bello ML, Dias LR, Vera MA, Nagashima T, Abreu PA, Santos MB, Albuquerque MG, Cabral LM, Freitas AC, Kalil MV, Rodrigues CR, Castro HC.

J Atheroscler Thromb. 2010 Jul 30;17(7):730-9. Epub 2010 Jun 2.

PMID:
20523012
[PubMed - indexed for MEDLINE]
Free Article
2.

Antibacterial profile against drug-resistant Staphylococcus epidermidis clinical strain and structure-activity relationship studies of 1H-pyrazolo[3,4-b]pyridine and thieno[2,3-b]pyridine derivatives.

Leal B, Afonso IF, Rodrigues CR, Abreu PA, Garrett R, Pinheiro LC, Azevedo AR, Borges JC, Vegi PF, Santos CC, da Silveira FC, Cabral LM, Frugulhetti IC, Bernardino AM, Santos DO, Castro HC.

Bioorg Med Chem. 2008 Sep 1;16(17):8196-204. doi: 10.1016/j.bmc.2008.07.035. Epub 2008 Jul 20.

PMID:
18701299
[PubMed - indexed for MEDLINE]
3.

Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives.

Zhao LM, Jin HS, Sun LP, Piao HR, Quan ZS.

Bioorg Med Chem Lett. 2005 Nov 15;15(22):5027-9.

PMID:
16169724
[PubMed - indexed for MEDLINE]
4.

Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: a new class of anti-inflammatory and anti-platelet agents.

Cardoso CR, de Brito FC, da Silva KC, de Miranda AL, Fraga CA, Barreiro EJ.

Bioorg Med Chem Lett. 2002 Jan 7;12(1):9-12.

PMID:
11738562
[PubMed - indexed for MEDLINE]
5.

Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation.

Levent S, Çalışkan B, Çiftçi M, Özkan Y, Yenicesu I, Ünver H, Banoglu E.

Eur J Med Chem. 2013 Jun;64:42-53. doi: 10.1016/j.ejmech.2013.03.048. Epub 2013 Apr 6.

PMID:
23639653
[PubMed - indexed for MEDLINE]
6.

Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition.

Brito FC, Kummerle AE, Lugnier C, Fraga CA, Barreiro EJ, Miranda AL.

Eur J Pharmacol. 2010 Jul 25;638(1-3):5-12. doi: 10.1016/j.ejphar.2010.04.003. Epub 2010 Apr 20.

PMID:
20412790
[PubMed - indexed for MEDLINE]
7.

New 1H-pyrazole-4-carboxamides with antiplatelet activity.

Rehse K, Kotthaus J, Khadembashi L.

Arch Pharm (Weinheim). 2009 Jan;342(1):27-33. doi: 10.1002/ardp.200800181.

PMID:
19051198
[PubMed - indexed for MEDLINE]
8.

Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity.

Wang WY, Hsieh PW, Wu YC, Wu CC.

Biochem Pharmacol. 2007 Aug 15;74(4):601-11. Epub 2007 Jun 3.

PMID:
17601492
[PubMed - indexed for MEDLINE]
9.

Antileishmanial pyrazolopyridine derivatives: synthesis and structure-activity relationship analysis.

de Mello H, Echevarria A, Bernardino AM, Canto-Cavalheiro M, Leon LL.

J Med Chem. 2004 Oct 21;47(22):5427-32.

PMID:
15481980
[PubMed - indexed for MEDLINE]
10.

Synthesis, antiplatelet and in silico evaluations of novel N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides.

Jordão AK, Ferreira VF, Lima ES, de Souza MC, Carlos EC, Castro HC, Geraldo RB, Rodrigues CR, Almeida MC, Cunha AC.

Bioorg Med Chem. 2009 May 15;17(10):3713-9. doi: 10.1016/j.bmc.2009.03.053. Epub 2009 Apr 1.

PMID:
19380229
[PubMed - indexed for MEDLINE]
11.

Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives.

Ferrarini PL, Badawneh M, Franconi F, Manera C, Miceli M, Mori C, Saccomanni G.

Farmaco. 2001 Apr;56(4):311-8.

PMID:
11421260
[PubMed - indexed for MEDLINE]
12.

Synthesis and antiplatelet activity of new imidazole-4-carboxylic acid derivatives.

Rehse K, Steege J.

Arch Pharm (Weinheim). 2005 Nov;338(11):539-47.

PMID:
16281307
[PubMed - indexed for MEDLINE]
13.

Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype.

Rodrigues AP, Costa LM, Santos BL, Maia RC, Miranda AL, Barreiro EJ, Fraga CA.

J Enzyme Inhib Med Chem. 2012 Feb;27(1):101-9. doi: 10.3109/14756366.2011.578575. Epub 2011 May 25.

PMID:
21612374
[PubMed - indexed for MEDLINE]
14.

New 2-amino-thiazole-4-acetamides with antiplatelet activity.

Rehse K, Baselt T.

Arch Pharm (Weinheim). 2008 Oct;341(10):645-54. doi: 10.1002/ardp.200700046.

PMID:
18720337
[PubMed - indexed for MEDLINE]
15.

Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation.

Koo KL, Ammit AJ, Tran VH, Duke CC, Roufogalis BD.

Thromb Res. 2001 Sep 1;103(5):387-97.

PMID:
11553371
[PubMed - indexed for MEDLINE]
16.

Investigation on the antiplatelet activity of pyrrolo[3,2-c]pyridine-containing compounds.

Voskressensky LG, de Candia M, Carotti A, Borisova TN, Kulikova LN, Varlamov AV, Altomare C.

J Pharm Pharmacol. 2003 Mar;55(3):323-32.

PMID:
12724037
[PubMed - indexed for MEDLINE]
17.

Structure-activity relationship studies on chalcone derivatives: potent inhibition of platelet aggregation.

Ko HH, Hsieh HK, Liu CT, Lin HC, Teng CM, Lin CN.

J Pharm Pharmacol. 2004 Oct;56(10):1333-7.

PMID:
15482650
[PubMed - indexed for MEDLINE]
18.
19.

Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series.

Dias LR, Santos MB, Albuquerque Sd, Castro HC, de Souza AM, Freitas AC, DiVaio MA, Cabral LM, Rodrigues CR.

Bioorg Med Chem. 2007 Jan 1;15(1):211-9. Epub 2006 Oct 1.

PMID:
17064907
[PubMed - indexed for MEDLINE]
20.

Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy.

Guthikonda S, Mangalpally K, Vaduganathan M, Patel R, Delao T, Bergeron AL, Dong JF, Lev EI, Kleiman NS.

Thromb Haemost. 2008 Jul;100(1):83-9. doi: 10.1160/TH07-10-0590.

PMID:
18612542
[PubMed - indexed for MEDLINE]

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