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Items: 1 to 20 of 110


Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.

Palkar PS, Borland MG, Naruhn S, Ferry CH, Lee C, Sk UH, Sharma AK, Amin S, Murray IA, Anderson CR, Perdew GH, Gonzalez FJ, Müller R, Peters JM.

Mol Pharmacol. 2010 Sep;78(3):419-30. doi: 10.1124/mol.110.065508. Epub 2010 Jun 1.


Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.

Borland MG, Foreman JE, Girroir EE, Zolfaghari R, Sharma AK, Amin S, Gonzalez FJ, Ross AC, Peters JM.

Mol Pharmacol. 2008 Nov;74(5):1429-42. doi: 10.1124/mol.108.050609. Epub 2008 Aug 7.


Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes.

Borland MG, Khozoie C, Albrecht PP, Zhu B, Lee C, Lahoti TS, Gonzalez FJ, Peters JM.

Cell Signal. 2011 Dec;23(12):2039-50. doi: 10.1016/j.cellsig.2011.07.020. Epub 2011 Aug 4.


Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes.

Burdick AD, Bility MT, Girroir EE, Billin AN, Willson TM, Gonzalez FJ, Peters JM.

Cell Signal. 2007 Jun;19(6):1163-71. Epub 2007 Jan 3.


Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.

Bility MT, Zhu B, Kang BH, Gonzalez FJ, Peters JM.

Toxicol Sci. 2010 Jan;113(1):27-36. doi: 10.1093/toxsci/kfp212. Epub 2009 Sep 11.


Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression.

Shan W, Palkar PS, Murray IA, McDevitt EI, Kennett MJ, Kang BH, Isom HC, Perdew GH, Gonzalez FJ, Peters JM.

Toxicol Sci. 2008 Oct;105(2):418-28. doi: 10.1093/toxsci/kfn142. Epub 2008 Jul 12.


Carnitine transporter OCTN2 and carnitine uptake in bovine kidney cells is regulated by peroxisome proliferator-activated receptor β/δ.

Zhou X, Ringseis R, Wen G, Eder K.

Acta Vet Scand. 2014 Apr 9;56:21. doi: 10.1186/1751-0147-56-21.


A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis.

Leisewitz AV, Urrutia CR, Martinez GR, Loyola G, Bronfman M.

J Cell Physiol. 2008 Nov;217(2):367-76. doi: 10.1002/jcp.21509.


Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.

Moulin D, Bianchi A, Boyault S, Sebillaud S, Koufany M, Francois M, Netter P, Jouzeau JY, Terlain B.

Arthritis Rheum. 2005 Mar;52(3):759-69.


Ligand-mediated regulation of peroxisome proliferator-activated receptor (PPAR) beta/delta: a comparative analysis of PPAR-selective agonists and all-trans retinoic acid.

Rieck M, Meissner W, Ries S, Müller-Brüsselbach S, Müller R.

Mol Pharmacol. 2008 Nov;74(5):1269-77. doi: 10.1124/mol.108.050625. Epub 2008 Aug 13.


PPARbeta/delta selectively induces differentiation and inhibits cell proliferation.

Kim DJ, Bility MT, Billin AN, Willson TM, Gonzalez FJ, Peters JM.

Cell Death Differ. 2006 Jan;13(1):53-60.


The role of peroxisome proliferator-activated receptor-beta/delta in epidermal growth factor-induced HaCaT cell proliferation.

Liang P, Jiang B, Yang X, Xiao X, Huang X, Long J, Zhang P, Zhang M, Xiao M, Xie T, Huang X.

Exp Cell Res. 2008 Oct 15;314(17):3142-51. doi: 10.1016/j.yexcr.2008.06.013. Epub 2008 Jun 24.


Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

Girroir EE, Hollingshead HE, Billin AN, Willson TM, Robertson GP, Sharma AK, Amin S, Gonzalez FJ, Peters JM.

Toxicology. 2008 Jan 14;243(1-2):236-43. Epub 2007 Nov 4.


Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.

Bility MT, Devlin-Durante MK, Blazanin N, Glick AB, Ward JM, Kang BH, Kennett MJ, Gonzalez FJ, Peters JM.

Carcinogenesis. 2008 Dec;29(12):2406-14. doi: 10.1093/carcin/bgn219. Epub 2008 Sep 17.


Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.

Khozoie C, Borland MG, Zhu B, Baek S, John S, Hager GL, Shah YM, Gonzalez FJ, Peters JM.

BMC Genomics. 2012 Nov 24;13:665. doi: 10.1186/1471-2164-13-665.


Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.

Sanderson LM, Degenhardt T, Koppen A, Kalkhoven E, Desvergne B, Müller M, Kersten S.

Mol Cell Biol. 2009 Dec;29(23):6257-67. doi: 10.1128/MCB.00370-09. Epub 2009 Oct 5. Erratum in: Mol Cell Biol. 2010 Oct;30(20):4977.


Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.

Borland MG, Krishnan P, Lee C, Albrecht PP, Shan W, Bility MT, Marcus CB, Lin JM, Amin S, Gonzalez FJ, Perdew GH, Peters JM.

Carcinogenesis. 2014 Jul;35(7):1602-12. doi: 10.1093/carcin/bgu067. Epub 2014 Mar 17.


High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties.

Naruhn S, Toth PM, Adhikary T, Kaddatz K, Pape V, Dörr S, Klebe G, Müller-Brüsselbach S, Diederich WE, Müller R.

Mol Pharmacol. 2011 Nov;80(5):828-38. doi: 10.1124/mol.111.074039. Epub 2011 Aug 23.

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