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Results: 1 to 20 of 162

1.

Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formation.

Harper K, Arsenault D, Boulay-Jean S, Lauzier A, Lucien F, Dubois CM.

Cancer Res. 2010 Jun 1;70(11):4634-43. doi: 10.1158/0008-5472.CAN-09-3813. Epub 2010 May 18.

PMID:
20484039
[PubMed - indexed for MEDLINE]
Free Article
2.

Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion.

Hoelzinger DB, Nakada M, Demuth T, Rosensteel T, Reavie LB, Berens ME.

J Neurooncol. 2008 Feb;86(3):297-309. Epub 2007 Oct 11.

PMID:
17928955
[PubMed - indexed for MEDLINE]
3.

Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, Arai H.

J Biol Chem. 2004 Apr 23;279(17):17634-9. Epub 2004 Jan 26.

PMID:
14744855
[PubMed - indexed for MEDLINE]
Free Article
4.

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts.

David M, Wannecq E, Descotes F, Jansen S, Deux B, Ribeiro J, Serre CM, Grès S, Bendriss-Vermare N, Bollen M, Saez S, Aoki J, Saulnier-Blache JS, Clézardin P, Peyruchaud O.

PLoS One. 2010 Mar 17;5(3):e9741. doi: 10.1371/journal.pone.0009741.

PMID:
20305819
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mammary tumorigenesis through LPA receptor signaling.

Jonkers J, Moolenaar WH.

Cancer Cell. 2009 Jun 2;15(6):457-9. doi: 10.1016/j.ccr.2009.05.003.

PMID:
19477423
[PubMed - indexed for MEDLINE]
Free Article
6.

Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells.

Ptaszynska MM, Pendrak ML, Bandle RW, Stracke ML, Roberts DD.

Mol Cancer Res. 2008 Mar;6(3):352-63. doi: 10.1158/1541-7786.MCR-07-0143.

PMID:
18337445
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.

Zhang R, Wang J, Ma S, Huang Z, Zhang G.

BMC Cell Biol. 2011 Mar 16;12:11. doi: 10.1186/1471-2121-12-11.

PMID:
21406114
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Autotaxin: a protein with two faces.

Tania M, Khan MA, Zhang H, Li J, Song Y.

Biochem Biophys Res Commun. 2010 Oct 29;401(4):493-7. doi: 10.1016/j.bbrc.2010.09.114. Epub 2010 Oct 1. Review.

PMID:
20888793
[PubMed - indexed for MEDLINE]
9.

Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions.

Nakasaki T, Tanaka T, Okudaira S, Hirosawa M, Umemoto E, Otani K, Jin S, Bai Z, Hayasaka H, Fukui Y, Aozasa K, Fujita N, Tsuruo T, Ozono K, Aoki J, Miyasaka M.

Am J Pathol. 2008 Nov;173(5):1566-76. doi: 10.2353/ajpath.2008.071153. Epub 2008 Sep 25.

PMID:
18818380
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

van Meeteren LA, Ruurs P, Stortelers C, Bouwman P, van Rooijen MA, Pradère JP, Pettit TR, Wakelam MJ, Saulnier-Blache JS, Mummery CL, Moolenaar WH, Jonkers J.

Mol Cell Biol. 2006 Jul;26(13):5015-22.

PMID:
16782887
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regulation and biological activities of the autotaxin-LPA axis.

van Meeteren LA, Moolenaar WH.

Prog Lipid Res. 2007 Mar;46(2):145-60. Epub 2007 Mar 16. Review.

PMID:
17459484
[PubMed - indexed for MEDLINE]
12.

ATX-LPA axis induces expression of OPN in hepatic cancer cell SMMC7721.

Zhang R, Zhang Z, Pan X, Huang X, Huang Z, Zhang G.

Anat Rec (Hoboken). 2011 Mar;294(3):406-11. doi: 10.1002/ar.21324. Epub 2010 Dec 31.

PMID:
21337710
[PubMed - indexed for MEDLINE]
Free Article
13.

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain.

Inoue M, Ma L, Aoki J, Chun J, Ueda H.

Mol Pain. 2008 Feb 8;4:6. doi: 10.1186/1744-8069-4-6.

PMID:
18261210
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis.

Li S, Wang B, Xu Y, Zhang J.

Mol Cancer. 2011 Feb 12;10:18. doi: 10.1186/1476-4598-10-18.

PMID:
21314984
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.

Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD.

Mol Cancer Res. 2010 Mar;8(3):309-21. doi: 10.1158/1541-7786.MCR-09-0288. Epub 2010 Mar 2.

PMID:
20197381
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood.

Endo T, Kano K, Motoki R, Hama K, Okudaira S, Ishida M, Ogiso H, Tanaka M, Matsuki N, Taguchi R, Kanai M, Shibasaki M, Arai H, Aoki J.

J Biochem. 2009 Aug;146(2):283-93. doi: 10.1093/jb/mvp068. Epub 2009 May 4.

PMID:
19416959
[PubMed - indexed for MEDLINE]
17.

Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia.

Khurana S, Tomar A, George SP, Wang Y, Siddiqui MR, Guo H, Tigyi G, Mathew S.

Exp Cell Res. 2008 Feb 1;314(3):530-42. Epub 2007 Nov 12.

PMID:
18054784
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulation of lysophosphatidate signaling by autotaxin and lipid phosphate phosphatases with respect to tumor progression, angiogenesis, metastasis and chemo-resistance.

Samadi N, Bekele R, Capatos D, Venkatraman G, Sariahmetoglu M, Brindley DN.

Biochimie. 2011 Jan;93(1):61-70. doi: 10.1016/j.biochi.2010.08.002. Epub 2010 Aug 13. Review.

PMID:
20709140
[PubMed - indexed for MEDLINE]
19.

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.

Liu S, Umezu-Goto M, Murph M, Lu Y, Liu W, Zhang F, Yu S, Stephens LC, Cui X, Murrow G, Coombes K, Muller W, Hung MC, Perou CM, Lee AV, Fang X, Mills GB.

Cancer Cell. 2009 Jun 2;15(6):539-50. doi: 10.1016/j.ccr.2009.03.027. Erratum in: Cancer Cell. 2009 Aug 4;16(2):172.

PMID:
19477432
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid.

Inoue M, Xie W, Matsushita Y, Chun J, Aoki J, Ueda H.

Neuroscience. 2008 Mar 18;152(2):296-8. doi: 10.1016/j.neuroscience.2007.12.041. Epub 2008 Jan 9.

PMID:
18280050
[PubMed - indexed for MEDLINE]

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