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Results: 1 to 20 of 114

1.

Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.

Karumuthil-Melethil S, Perez N, Li R, Prabhakar BS, Holterman MJ, Vasu C.

J Immunol. 2010 Jun 15;184(12):6695-708. doi: 10.4049/jimmunol.0903130. Epub 2010 May 14.

PMID:
20483724
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+) -adaptive regulatory T cell generation.

Perez N, Karumuthil-Melethil S, Li R, Prabhakar BS, Holterman MJ, Vasu C.

J Immunol. 2008 May 15;180(10):6566-76.

PMID:
18453575
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells.

Li R, Perez N, Karumuthil-Melethil S, Prabhakar BS, Holterman MJ, Vasu C.

J Immunol. 2007 Oct 15;179(8):5191-203.

PMID:
17911604
[PubMed - indexed for MEDLINE]
Free Article
4.

Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.

Vasu C, Prabhakar BS, Holterman MJ.

J Immunol. 2004 Aug 15;173(4):2866-76.

PMID:
15295006
[PubMed - indexed for MEDLINE]
Free Article
5.

Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes.

Katz JD, Ondr JK, Opoka RJ, Garcia Z, Janssen EM.

J Immunol. 2010 Aug 15;185(4):1999-2003. doi: 10.4049/jimmunol.1001398. Epub 2010 Jul 19.

PMID:
20644171
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion.

Turner MS, Kane LP, Morel PA.

J Immunol. 2009 Oct 15;183(8):4895-903. doi: 10.4049/jimmunol.0901459.

PMID:
19801514
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Transgenic expression of single-chain anti-CTLA-4 Fv on beta cells protects nonobese diabetic mice from autoimmune diabetes.

Shieh SJ, Chou FC, Yu PN, Lin WC, Chang DM, Roffler SR, Sytwu HK.

J Immunol. 2009 Aug 15;183(4):2277-85. doi: 10.4049/jimmunol.0900679. Epub 2009 Jul 27.

PMID:
19635924
[PubMed - indexed for MEDLINE]
Free Article
9.

CTLA-4 is expressed by human monocyte-derived dendritic cells and regulates their functions.

Laurent S, Carrega P, Saverino D, Piccioli P, Camoriano M, Morabito A, Dozin B, Fontana V, Simone R, Mortara L, Mingari MC, Ferlazzo G, Pistillo MP.

Hum Immunol. 2010 Oct;71(10):934-41. doi: 10.1016/j.humimm.2010.07.007. Epub 2010 Aug 1.

PMID:
20650297
[PubMed - indexed for MEDLINE]
10.
11.

Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.

Petzold C, Riewaldt J, Koenig T, Schallenberg S, Kretschmer K.

Rev Diabet Stud. 2010 Spring;7(1):47-61. doi: 10.1900/RDS.2010.7.47. Epub 2010 May 10.

PMID:
20703438
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A novel pancreatic β-cell targeting bispecific-antibody (BsAb) can prevent the development of type 1 diabetes in NOD mice.

Bhattacharya P, Fan J, Haddad C, Essani A, Gopisetty A, Elshabrawy HA, Vasu C, Prabhakar BS.

Clin Immunol. 2014 Jul;153(1):187-98. doi: 10.1016/j.clim.2014.04.014. Epub 2014 May 2.

PMID:
24792135
[PubMed - indexed for MEDLINE]
13.

Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells.

Machen J, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N.

J Immunol. 2004 Oct 1;173(7):4331-41.

PMID:
15383562
[PubMed - indexed for MEDLINE]
Free Article
14.

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice.

Han J, Zhong J, Wei W, Wang Y, Huang Y, Yang P, Purohit S, Dong Z, Wang MH, She JX, Gong F, Stern DM, Wang CY.

Diabetes. 2008 Aug;57(8):2118-27. doi: 10.2337/db07-1499. Epub 2008 May 13.

PMID:
18477810
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8/RIP-B7.1 mice.

Tai N, Yasuda H, Xiang Y, Zhang L, Rodriguez-Pinto D, Yokono K, Sherwin R, Wong FS, Nagata M, Wen L.

Clin Immunol. 2011 Jun;139(3):336-49. doi: 10.1016/j.clim.2011.03.003. Epub 2011 Mar 9.

PMID:
21458378
[PubMed - indexed for MEDLINE]
16.

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6374-9. doi: 10.1073/pnas.0802644105. Epub 2008 Apr 22.

PMID:
18430797
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

Fife BT, Griffin MD, Abbas AK, Locksley RM, Bluestone JA.

J Clin Invest. 2006 Aug;116(8):2252-61.

PMID:
16886063
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.

Price JD, Beauchamp NM, Rahir G, Zhao Y, Rieger CC, Lau-Kilby AW, Tarbell KV.

J Leukoc Biol. 2014 Feb;95(2):325-36. doi: 10.1189/jlb.0113013. Epub 2013 Sep 30.

PMID:
24082013
[PubMed - indexed for MEDLINE]
20.

Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens.

Dai YD, Marrero IG, Gros P, Zaghouani H, Wicker LS, Sercarz EE.

Diabetes. 2009 Jan;58(1):156-64. doi: 10.2337/db07-1608. Epub 2008 Nov 4.

PMID:
18984740
[PubMed - indexed for MEDLINE]
Free PMC Article
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