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Results: 1 to 20 of 89

1.

From the bench to the clinic and back again: translational biomarker discovery using in silico mining of pharmacogenomic data.

Mendrick DL, Daniels KK.

Biomark Med. 2007 Aug;1(2):319-33. doi: 10.2217/17520363.1.2.319.

PMID:
20477406
[PubMed]
2.

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.

Amacher DE.

Toxicol Appl Pharmacol. 2010 May 15;245(1):134-42. doi: 10.1016/j.taap.2010.02.011. Epub 2010 Feb 26. Review.

PMID:
20219512
[PubMed - indexed for MEDLINE]
3.

The long journey of cancer biomarkers from the bench to the clinic.

Pavlou MP, Diamandis EP, Blasutig IM.

Clin Chem. 2013 Jan;59(1):147-57. doi: 10.1373/clinchem.2012.184614. Epub 2012 Sep 27. Review.

PMID:
23019307
[PubMed - indexed for MEDLINE]
Free Article
4.

From pharmacogenomics to translational biomarkers.

Mendrick DL.

Methods Mol Biol. 2008;460:195-220. doi: 10.1007/978-1-60327-048-9_10.

PMID:
18449489
[PubMed - indexed for MEDLINE]
5.

Biomarkers to Enable the Development of Neuroprotective Therapies for Huntington’s Disease.

Hersch SM, Rosas HD.

In: Lo DC, Hughes RE, editors. Neurobiology of Huntington's Disease: Applications to Drug Discovery. Boca Raton (FL): CRC Press; 2011. Chapter 11.

6.

Pharmacogenomic testing and antithrombotic therapy: ready for prime time?

Holmes DR Jr.

Rambam Maimonides Med J. 2013 Jan 30;4(1):e0005. doi: 10.5041/RMMJ.10105. Print 2013 Jan.

PMID:
23908855
[PubMed]
Free PMC Article
7.

Regulatory approval for new pharmacogenomic tests: a comparative overview.

Joly Y, Koutrikas G, Tassé AM, Issa A, Carleton B, Hayden M, Rieder MJ, Ramos-Paque E, Avard D.

Food Drug Law J. 2011;66(1):1-24, i. Review.

PMID:
24505844
[PubMed - indexed for MEDLINE]
8.

Toxicogenomics and cross-species biomarker discovery: applications in drug discovery and safety assessment.

Orr MS.

Toxicol Mech Methods. 2006;16(2-3):79-87. doi: 10.1080/15376520600558317.

PMID:
20021000
[PubMed]
9.

Cancer Drug Development: New Targets for Cancer Treatment.

Curt GA.

Oncologist. 1996;1(3):II-III.

PMID:
10387987
[PubMed - as supplied by publisher]
10.

Biomarkers in drug discovery and development: from target identification through drug marketing.

Colburn WA.

J Clin Pharmacol. 2003 Apr;43(4):329-41. Review.

PMID:
12723454
[PubMed - indexed for MEDLINE]
11.

Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation.

Greco I, Day N, Riddoch-Contreras J, Reed J, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Mecocci P, Wahlund LO, Simmons A, Barnes J, Lovestone S.

J Transl Med. 2012 Oct 31;10:217. doi: 10.1186/1479-5876-10-217.

PMID:
23113945
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Implementing the 2009 Institute of Medicine recommendations on resident physician work hours, supervision, and safety.

Blum AB, Shea S, Czeisler CA, Landrigan CP, Leape L.

Nat Sci Sleep. 2011 Jun 24;3:47-85. doi: 10.2147/NSS.S19649. Print 2011.

PMID:
23616719
[PubMed]
Free PMC Article
13.

Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer.

Yang Y, Pospisil P, Iyer LK, Adelstein SJ, Kassis AI.

PLoS One. 2008;3(11):e3661. doi: 10.1371/journal.pone.0003661. Epub 2008 Nov 6. Erratum in: PLoS ONE. 2009;4(1). doi: 10.1371/annotation/9fbf88b3-5041-4a5e-b569-bc6c0e5f9c29. Pospisil, Pavel [added].

PMID:
18987750
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genomic and genetic biomarkers of toxicity.

Mendrick DL.

Toxicology. 2008 Mar 20;245(3):175-81. doi: 10.1016/j.tox.2007.11.013. Epub 2007 Nov 28. Review.

PMID:
18206287
[PubMed - indexed for MEDLINE]
15.

Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.

Agúndez JA, Del Barrio J, Padró T, Stephens C, Farré M, Andrade RJ, Badimon L, García-Martín E, Vilahur G, Lucena MI.

Front Pharmacol. 2012 Jan 19;3:2. doi: 10.3389/fphar.2012.00002. eCollection 2012.

PMID:
22294980
[PubMed]
Free PMC Article
16.

Current trends and strategic directions in the use of pharmacogenomics to identify translational biomarkers.

Mendrick DL.

Curr Opin Drug Discov Devel. 2007 Jan;10(1):37-42. Review.

PMID:
17265739
[PubMed - indexed for MEDLINE]
17.

Emerging Safety Science: Workshop Summary.

Institute of Medicine (US) Forum on Drug Discovery, Development, and Translation.

Washington (DC): National Academies Press (US); 2008.

18.

Multiplex assays for biomarker research and clinical application: translational science coming of age.

Fu Q, Schoenhoff FS, Savage WJ, Zhang P, Van Eyk JE.

Proteomics Clin Appl. 2010 Mar;4(3):271-84. doi: 10.1002/prca.200900217. Epub 2010 Jan 7. Review.

PMID:
21137048
[PubMed - indexed for MEDLINE]
19.

Novel diagnostic biomarkers for prostate cancer.

Madu CO, Lu Y.

J Cancer. 2010 Oct 6;1:150-77.

PMID:
20975847
[PubMed]
Free PMC Article
20.

Proteomic-based biomarker discovery with emphasis on cerebrospinal fluid and multiple sclerosis.

Berven FS, Flikka K, Berle M, Vedeler C, Ulvik RJ.

Curr Pharm Biotechnol. 2006 Jun;7(3):147-58. Review.

PMID:
16789900
[PubMed - indexed for MEDLINE]

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