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Items: 1 to 20 of 109

1.

Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.

Lazer G, Pe'er L, Farago M, Machida K, Mayer BJ, Katzav S.

J Biol Chem. 2010 Jul 23;285(30):23075-85. doi: 10.1074/jbc.M109.094508. Epub 2010 May 10.

2.

The association of Sam68 with Vav1 contributes to tumorigenesis.

Lazer G, Pe'er L, Schapira V, Richard S, Katzav S.

Cell Signal. 2007 Dec;19(12):2479-86. Epub 2007 Aug 8.

PMID:
17855053
3.
4.

Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.

Groysman M, Hornstein I, Alcover A, Katzav S.

J Biol Chem. 2002 Dec 20;277(51):50121-30. Epub 2002 Oct 16.

5.

Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.

Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K.

Biochemistry. 2005 Mar 15;44(10):3891-8.

PMID:
15751964
6.

The N-terminal 20-amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor-mediated calcium signaling.

Li SY, Du MJ, Wan YJ, Lan B, Liu YH, Yang Y, Zhang CZ, Cao Y.

J Biol Chem. 2013 Feb 8;288(6):3777-85. doi: 10.1074/jbc.M112.426221. Epub 2012 Dec 27.

7.

Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.

Charvet C, Canonigo AJ, Billadeau DD, Altman A.

J Biol Chem. 2005 Apr 15;280(15):15289-99. Epub 2005 Feb 11.

8.

Mutation of Vav1 adaptor region reveals a new oncogenic activation.

Razanadrakoto L, Cormier F, Laurienté V, Dondi E, Gardano L, Katzav S, Guittat L, Varin-Blank N.

Oncotarget. 2015 Feb 10;6(4):2524-37.

9.

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.

Chen CH, Martin VA, Gorenstein NM, Geahlen RL, Post CB.

Mol Cell Biol. 2011 Jul;31(14):2984-96. doi: 10.1128/MCB.05043-11. Epub 2011 May 23.

10.

Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation.

Miletic AV, Sakata-Sogawa K, Hiroshima M, Hamann MJ, Gomez TS, Ota N, Kloeppel T, Kanagawa O, Tokunaga M, Billadeau DD, Swat W.

J Biol Chem. 2006 Dec 15;281(50):38257-65. Epub 2006 Oct 18.

11.
12.

Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.

Sylvain NR, Nguyen K, Bunnell SC.

Sci Signal. 2011 Mar 8;4(163):ra14. doi: 10.1126/scisignal.2001178.

13.

Vav family proteins couple to diverse cell surface receptors.

Moores SL, Selfors LM, Fredericks J, Breit T, Fujikawa K, Alt FW, Brugge JS, Swat W.

Mol Cell Biol. 2000 Sep;20(17):6364-73.

15.

Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT.

Shukla U, Hatani T, Nakashima K, Ogi K, Sada K.

J Biol Chem. 2009 Dec 4;284(49):33719-28. doi: 10.1074/jbc.M109.049999. Epub 2009 Oct 15.

16.

Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.

Chrencik JE, Brooun A, Zhang H, Mathews II, Hura GL, Foster SA, Perry JJ, Streiff M, Ramage P, Widmer H, Bokoch GM, Tainer JA, Weckbecker G, Kuhn P.

J Mol Biol. 2008 Jul 25;380(5):828-43. doi: 10.1016/j.jmb.2008.05.024. Epub 2008 May 17.

17.

Vav1: a hematopoietic signal transduction molecule involved in human malignancies.

Katzav S.

Int J Biochem Cell Biol. 2009 Jun;41(6):1245-8. doi: 10.1016/j.biocel.2008.11.006. Epub 2008 Nov 30. Review.

PMID:
19100858
18.

Vav1: an oncogene that regulates specific transcriptional activation of T cells.

Katzav S.

Blood. 2004 Apr 1;103(7):2443-51. Epub 2003 Oct 30. Review.

19.

Human Vav1 expression in hematopoietic and cancer cell lines is regulated by c-Myb and by CpG methylation.

Ilan L, Katzav S.

PLoS One. 2012;7(1):e29939. doi: 10.1371/journal.pone.0029939. Epub 2012 Jan 11.

20.
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