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Items: 1 to 20 of 77

1.

Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping.

Hsu PY, Hsu HK, Singer GA, Yan PS, Rodriguez BA, Liu JC, Weng YI, Deatherage DE, Chen Z, Pereira JS, Lopez R, Russo J, Wang Q, Lamartiniere CA, Nephew KP, Huang TH.

Genome Res. 2010 Jun;20(6):733-44. doi: 10.1101/gr.101923.109. Epub 2010 May 4.

2.

Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.

Rodriguez BA, Weng YI, Liu TM, Zuo T, Hsu PY, Lin CH, Cheng AL, Cui H, Yan PS, Huang TH.

Carcinogenesis. 2011 Jun;32(6):812-21. doi: 10.1093/carcin/bgr017. Epub 2011 Feb 8.

3.

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer.

Hon GC, Hawkins RD, Caballero OL, Lo C, Lister R, Pelizzola M, Valsesia A, Ye Z, Kuan S, Edsall LE, Camargo AA, Stevenson BJ, Ecker JR, Bafna V, Strausberg RL, Simpson AJ, Ren B.

Genome Res. 2012 Feb;22(2):246-58. doi: 10.1101/gr.125872.111. Epub 2011 Dec 7.

4.

Epigenetic repression of the estrogen-regulated Homeobox B13 gene in breast cancer.

Rodriguez BA, Cheng AS, Yan PS, Potter D, Agosto-Perez FJ, Shapiro CL, Huang TH.

Carcinogenesis. 2008 Jul;29(7):1459-65. doi: 10.1093/carcin/bgn115. Epub 2008 May 21.

5.

Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells.

Putnik M, Zhao C, Gustafsson JÅ, Dahlman-Wright K.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):26-32. doi: 10.1016/j.bbrc.2012.08.007. Epub 2012 Aug 10.

PMID:
22902638
6.

ESR1 gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients.

Martínez-Galán J, Torres-Torres B, Núñez MI, López-Peñalver J, Del Moral R, Ruiz De Almodóvar JM, Menjón S, Concha A, Chamorro C, Ríos S, Delgado JR.

BMC Cancer. 2014 Feb 4;14:59. doi: 10.1186/1471-2407-14-59.

7.

Long range epigenetic silencing is a trans-species mechanism that results in cancer specific deregulation by overriding the chromatin domains of normal cells.

Forn M, Muñoz M, Tauriello DV, Merlos-Suárez A, Rodilla V, Bigas A, Batlle E, Jordà M, Peinado MA.

Mol Oncol. 2013 Dec;7(6):1129-41. doi: 10.1016/j.molonc.2013.08.008. Epub 2013 Aug 30.

8.

Pattern of expression of genes linked to epigenetic silencing in human breast cancer.

Munot K, Bell SM, Lane S, Horgan K, Hanby AM, Speirs V.

Hum Pathol. 2006 Aug;37(8):989-99.

PMID:
16867861
9.

Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity.

Coolen MW, Stirzaker C, Song JZ, Statham AL, Kassir Z, Moreno CS, Young AN, Varma V, Speed TP, Cowley M, Lacaze P, Kaplan W, Robinson MD, Clark SJ.

Nat Cell Biol. 2010 Mar;12(3):235-46. doi: 10.1038/ncb2023. Epub 2010 Feb 21.

10.

PcG proteins, DNA methylation, and gene repression by chromatin looping.

Tiwari VK, McGarvey KM, Licchesi JD, Ohm JE, Herman JG, Schübeler D, Baylin SB.

PLoS Biol. 2008 Dec 2;6(12):2911-27. doi: 10.1371/journal.pbio.0060306.

11.

ERE-independent ERalpha target genes differentially expressed in human breast tumors.

Glidewell-Kenney C, Weiss J, Lee EJ, Pillai S, Ishikawa T, Ariazi EA, Jameson JL.

Mol Cell Endocrinol. 2005 Dec 21;245(1-2):53-9. Epub 2005 Nov 17.

PMID:
16298037
12.

Cancer epigenetics: a perspective on the role of DNA methylation in acquired endocrine resistance.

Trimarchi MP, Mouangsavanh M, Huang TH.

Chin J Cancer. 2011 Nov;30(11):749-56. doi: 10.5732/cjc.011.10128. Review.

13.

Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue.

Yan PS, Venkataramu C, Ibrahim A, Liu JC, Shen RZ, Diaz NM, Centeno B, Weber F, Leu YW, Shapiro CL, Eng C, Yeatman TJ, Huang TH.

Clin Cancer Res. 2006 Nov 15;12(22):6626-36.

14.

Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer.

Rafique S, Thomas JS, Sproul D, Bickmore WA.

Genome Biol. 2015 Aug 3;16:145. doi: 10.1186/s13059-015-0719-9.

15.

Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells.

Fleury L, Gerus M, Lavigne AC, Richard-Foy H, Bystricky K.

Oncogene. 2008 Jul 3;27(29):4075-85. doi: 10.1038/onc.2008.41. Epub 2008 Mar 3.

PMID:
18317449
16.

Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis.

Clark SJ.

Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R88-95. Review.

17.

DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium.

Plachot C, Lelièvre SA.

Exp Cell Res. 2004 Aug 1;298(1):122-32.

PMID:
15242767
18.

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

Bhat-Nakshatri P, Wang G, Appaiah H, Luktuke N, Carroll JS, Geistlinger TR, Brown M, Badve S, Liu Y, Nakshatri H.

Mol Cell Biol. 2008 Dec;28(24):7487-503. doi: 10.1128/MCB.00799-08. Epub 2008 Oct 6.

19.

Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer.

Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH.

Cancer Res. 2004 Nov 15;64(22):8184-92.

20.

Epigenetic inactivation of the HOXA gene cluster in breast cancer.

Novak P, Jensen T, Oshiro MM, Wozniak RJ, Nouzova M, Watts GS, Klimecki WT, Kim C, Futscher BW.

Cancer Res. 2006 Nov 15;66(22):10664-70. Epub 2006 Nov 6.

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