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Items: 1 to 20 of 354


Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.

Abbadie C, McManus OB, Sun SY, Bugianesi RM, Dai G, Haedo RJ, Herrington JB, Kaczorowski GJ, Smith MM, Swensen AM, Warren VA, Williams B, Arneric SP, Eduljee C, Snutch TP, Tringham EW, Jochnowitz N, Liang A, Euan MacIntyre D, McGowan E, Mistry S, White VV, Hoyt SB, London C, Lyons KA, Bunting PB, Volksdorf S, Duffy JL.

J Pharmacol Exp Ther. 2010 Aug;334(2):545-55. doi: 10.1124/jpet.110.166363. Epub 2010 May 3.


Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.

Swensen AM, Herrington J, Bugianesi RM, Dai G, Haedo RJ, Ratliff KS, Smith MM, Warren VA, Arneric SP, Eduljee C, Parker D, Snutch TP, Hoyt SB, London C, Duffy JL, Kaczorowski GJ, McManus OB.

Mol Pharmacol. 2012 Mar;81(3):488-97. doi: 10.1124/mol.111.075226. Epub 2011 Dec 21.


Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.

Patel R, Rutten K, Valdor M, Schiene K, Wigge S, Schunk S, Damann N, Christoph T, Dickenson AH.

Neuroscience. 2015 Jun 25;297:47-57. doi: 10.1016/j.neuroscience.2015.03.057. Epub 2015 Apr 1.


Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels.

Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ.

Mol Pharmacol. 2010 Feb;77(2):139-48. doi: 10.1124/mol.109.058834. Epub 2009 Nov 5.


Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels.

Motin L, Yasuda T, Schroeder CI, Lewis RJ, Adams DJ.

Eur J Neurosci. 2007 Jan;25(2):435-44.


Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation.

Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ.

J Neurosci. 2008 Oct 22;28(43):10943-51. doi: 10.1523/JNEUROSCI.3594-08.2008.


Inhibition of insect calcium channels by huwentoxin-V, a neurotoxin from Chinese tarantula Ornithoctonus huwena venom.

Deng M, Luo X, Meng E, Xiao Y, Liang S.

Eur J Pharmacol. 2008 Mar 17;582(1-3):12-6. doi: 10.1016/j.ejphar.2007.12.014. Epub 2007 Dec 27.


Functional compartmentalization of opioid desensitization in primary sensory neurons.

Samoriski GM, Gross RA.

J Pharmacol Exp Ther. 2000 Aug;294(2):500-9.


CaV2.2 and CaV2.3 (N- and R-type) Ca2+ channels in depolarization-evoked entry of Ca2+ into mouse sperm.

Wennemuth G, Westenbroek RE, Xu T, Hille B, Babcock DF.

J Biol Chem. 2000 Jul 14;275(28):21210-7.


Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena.

Deng M, Luo X, Xiao Y, Sun Z, Jiang L, Liu Z, Zeng X, Chen H, Tang J, Zeng W, Songping Liang.

Neuropharmacology. 2014 Apr;79:657-67. doi: 10.1016/j.neuropharm.2014.01.017. Epub 2014 Jan 24.


Inhibition of human recombinant T-type calcium channels by the endocannabinoid N-arachidonoyl dopamine.

Ross HR, Gilmore AJ, Connor M.

Br J Pharmacol. 2009 Mar;156(5):740-50. doi: 10.1111/j.1476-5381.2008.00072.x. Epub 2009 Feb 16.


Voltage-gated calcium currents in axotomized adult rat cutaneous afferent neurons.

Baccei ML, Kocsis JD.

J Neurophysiol. 2000 Apr;83(4):2227-38.


Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

Gerevich Z, Borvendeg SJ, Schröder W, Franke H, Wirkner K, Nörenberg W, Fürst S, Gillen C, Illes P.

J Neurosci. 2004 Jan 28;24(4):797-807.


Low-threshold L-type calcium channels in rat dopamine neurons.

Durante P, Cardenas CG, Whittaker JA, Kitai ST, Scroggs RS.

J Neurophysiol. 2004 Mar;91(3):1450-4. Epub 2003 Nov 26.

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