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Results: 1 to 20 of 166

1.

Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis.

Novarino G, Weinert S, Rickheit G, Jentsch TJ.

Science. 2010 Jun 11;328(5984):1398-401. doi: 10.1126/science.1188070. Epub 2010 Apr 29.

PMID:
20430975
[PubMed - indexed for MEDLINE]
Free Article
2.

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins.

Scheel O, Zdebik AA, Lourdel S, Jentsch TJ.

Nature. 2005 Jul 21;436(7049):424-7.

PMID:
16034422
[PubMed - indexed for MEDLINE]
3.

The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease.

Günther W, Piwon N, Jentsch TJ.

Pflugers Arch. 2003 Jan;445(4):456-62. Epub 2002 Nov 29. Review.

PMID:
12548389
[PubMed - indexed for MEDLINE]
4.

ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.

Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman AS.

J Biol Chem. 2005 Jan 14;280(2):1241-7. Epub 2004 Oct 25.

PMID:
15504734
[PubMed - indexed for MEDLINE]
Free Article
5.

Chloride transport in the kidney: lessons from human disease and knockout mice.

Jentsch TJ.

J Am Soc Nephrol. 2005 Jun;16(6):1549-61. Epub 2005 Apr 13.

PMID:
15829707
[PubMed - indexed for MEDLINE]
Free Article
6.

Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation.

Weinert S, Jabs S, Supanchart C, Schweizer M, Gimber N, Richter M, Rademann J, Stauber T, Kornak U, Jentsch TJ.

Science. 2010 Jun 11;328(5984):1401-3. doi: 10.1126/science.1188072.

PMID:
20430974
[PubMed - indexed for MEDLINE]
Free Article
7.

Chloride channels and endocytosis: new insights from Dent's disease and ClC-5 knockout mice.

Devuyst O, Jouret F, Auzanneau C, Courtoy PJ.

Nephron Physiol. 2005;99(3):p69-73. Review.

PMID:
15637424
[PubMed - indexed for MEDLINE]
8.

The chloride channel ClC-4 contributes to endosomal acidification and trafficking.

Mohammad-Panah R, Harrison R, Dhani S, Ackerley C, Huan LJ, Wang Y, Bear CE.

J Biol Chem. 2003 Aug 1;278(31):29267-77. Epub 2003 May 13.

PMID:
12746443
[PubMed - indexed for MEDLINE]
Free Article
9.

ClC-5: a chloride channel with multiple roles in renal tubular albumin uptake.

Hryciw DH, Ekberg J, Pollock CA, Poronnik P.

Int J Biochem Cell Biol. 2006;38(7):1036-42. Epub 2005 Oct 3. Review.

PMID:
16226913
[PubMed - indexed for MEDLINE]
10.

An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.

Schwake M, Friedrich T, Jentsch TJ.

J Biol Chem. 2001 Apr 13;276(15):12049-54. Epub 2000 Dec 14.

PMID:
11116157
[PubMed - indexed for MEDLINE]
Free Article
11.

Direct endosomal acidification by the outwardly rectifying CLC-5 Cl(-)/H(+) exchanger.

Smith AJ, Lippiat JD.

J Physiol. 2010 Jun 15;588(Pt 12):2033-45. doi: 10.1113/jphysiol.2010.188540. Epub 2010 Apr 26.

PMID:
20421284
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Impaired acidification in early endosomes of ClC-5 deficient proximal tubule.

Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS.

Biochem Biophys Res Commun. 2005 Apr 15;329(3):941-6.

PMID:
15752747
[PubMed - indexed for MEDLINE]
13.

Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients.

Moulin P, Igarashi T, Van der Smissen P, Cosyns JP, Verroust P, Thakker RV, Scheinman SJ, Courtoy PJ, Devuyst O.

Kidney Int. 2003 Apr;63(4):1285-95.

PMID:
12631345
[PubMed - indexed for MEDLINE]
14.

Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.

Wang SS, Devuyst O, Courtoy PJ, Wang XT, Wang H, Wang Y, Thakker RV, Guggino S, Guggino WB.

Hum Mol Genet. 2000 Dec 12;9(20):2937-45.

PMID:
11115837
[PubMed - indexed for MEDLINE]
Free Article
15.

Chloride channels and endocytosis: new insights from Dent's disease and CLC-5 knockout mice.

Devuyst O.

Bull Mem Acad R Med Belg. 2004;159(Pt 2):212-7. Review.

PMID:
15615095
[PubMed - indexed for MEDLINE]
16.

Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.

Jentsch TJ.

J Physiol. 2007 Feb 1;578(Pt 3):633-40. Epub 2006 Nov 16.

PMID:
17110406
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.

Piwon N, Günther W, Schwake M, Bösl MR, Jentsch TJ.

Nature. 2000 Nov 16;408(6810):369-73.

PMID:
11099045
[PubMed - indexed for MEDLINE]
18.

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

Picollo A, Pusch M.

Nature. 2005 Jul 21;436(7049):420-3.

PMID:
16034421
[PubMed - indexed for MEDLINE]
19.

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.

Reed AA, Loh NY, Terryn S, Lippiat JD, Partridge C, Galvanovskis J, Williams SE, Jouret F, Wu FT, Courtoy PJ, Nesbit MA, Rorsman P, Devuyst O, Ashcroft FM, Thakker RV.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F365-80. doi: 10.1152/ajprenal.00038.2009. Epub 2009 Nov 25.

PMID:
19940036
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Novel CLCN5 mutations in patients with Dent's disease result in altered ion currents or impaired exchanger processing.

Grand T, Mordasini D, L'Hoste S, Pennaforte T, Genete M, Biyeyeme MJ, Vargas-Poussou R, Blanchard A, Teulon J, Lourdel S.

Kidney Int. 2009 Nov;76(9):999-1005. doi: 10.1038/ki.2009.305. Epub 2009 Aug 5.

PMID:
19657328
[PubMed - indexed for MEDLINE]
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