Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 130

1.

The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions.

Hegazy SA, Wang P, Anand M, Ingham RJ, Gelebart P, Lai R.

J Biol Chem. 2010 Jun 25;285(26):19813-20. doi: 10.1074/jbc.M110.121988. Epub 2010 Apr 27.

PMID:
20424160
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

SHP1 tyrosine phosphatase negatively regulates NPM-ALK tyrosine kinase signaling.

Honorat JF, Ragab A, Lamant L, Delsol G, Ragab-Thomas J.

Blood. 2006 May 15;107(10):4130-8. Epub 2006 Feb 9.

PMID:
16469875
[PubMed - indexed for MEDLINE]
Free Article
4.

Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J.

J Biol Chem. 2003 Aug 8;278(32):30028-36. Epub 2003 May 14.

PMID:
12748172
[PubMed - indexed for MEDLINE]
Free Article
5.

Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry.

Wang P, Wu F, Ma Y, Li L, Lai R, Young LC.

J Biol Chem. 2010 Jan 1;285(1):95-103. doi: 10.1074/jbc.M109.059758. Epub 2009 Nov 2.

PMID:
19887368
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma.

Han Y, Amin HM, Franko B, Frantz C, Shi X, Lai R.

Blood. 2006 Oct 15;108(8):2796-803. Epub 2006 Jul 6.

PMID:
16825495
[PubMed - indexed for MEDLINE]
Free Article
7.

Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growth.

Riera L, Lasorsa E, Ambrogio C, Surrenti N, Voena C, Chiarle R.

J Biol Chem. 2010 Aug 20;285(34):26441-50. doi: 10.1074/jbc.M110.116327. Epub 2010 Jun 16.

PMID:
20554525
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential.

Wang P, Wu F, Zhang J, McMullen T, Young LC, Ingham RJ, Li L, Lai R.

Carcinogenesis. 2011 Feb;32(2):146-53. doi: 10.1093/carcin/bgq229. Epub 2010 Nov 2.

PMID:
21045017
[PubMed - indexed for MEDLINE]
Free Article
9.

Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis.

Bischof D, Pulford K, Mason DY, Morris SW.

Mol Cell Biol. 1997 Apr;17(4):2312-25.

PMID:
9121481
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.

Voena C, Conte C, Ambrogio C, Boeri Erba E, Boccalatte F, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.

Cancer Res. 2007 May 1;67(9):4278-86.

PMID:
17483340
[PubMed - indexed for MEDLINE]
Free Article
11.

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.

Oncogene. 2007 Aug 16;26(38):5606-14. Epub 2007 Mar 12.

PMID:
17353907
[PubMed - indexed for MEDLINE]
12.

Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.

Cussac D, Greenland C, Roche S, Bai RY, Duyster J, Morris SW, Delsol G, Allouche M, Payrastre B.

Blood. 2004 Feb 15;103(4):1464-71. Epub 2003 Oct 16.

PMID:
14563642
[PubMed - indexed for MEDLINE]
Free Article
13.

Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA.

Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA.

Oncogene. 2011 Mar 17;30(11):1372-8. doi: 10.1038/onc.2010.505. Epub 2010 Nov 22.

PMID:
21102525
[PubMed - indexed for MEDLINE]
14.
16.

Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase.

Tartari CJ, Gunby RH, Coluccia AM, Sottocornola R, Cimbro B, Scapozza L, Donella-Deana A, Pinna LA, Gambacorti-Passerini C.

J Biol Chem. 2008 Feb 15;283(7):3743-50. Epub 2007 Dec 10.

PMID:
18070884
[PubMed - indexed for MEDLINE]
Free Article
17.

A "liaison dangereuse" between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK.

Fawal M, Armstrong F, Ollier S, Dupont H, Touriol C, Monsarrat B, Delsol G, Payrastre B, Morello D.

Blood. 2006 Oct 15;108(8):2780-8. Epub 2006 Jul 11.

PMID:
16835382
[PubMed - indexed for MEDLINE]
Free Article
18.

Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation.

Chikamori M, Fujimoto J, Tokai-Nishizumi N, Yamamoto T.

Oncogene. 2007 May 3;26(20):2950-4. Epub 2006 Nov 6.

PMID:
17086210
[PubMed - indexed for MEDLINE]
19.

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma.

Zhang Q, Raghunath PN, Xue L, Majewski M, Carpentieri DF, Odum N, Morris S, Skorski T, Wasik MA.

J Immunol. 2002 Jan 1;168(1):466-74.

PMID:
11751994
[PubMed - indexed for MEDLINE]
Free Article
20.

Molecular and functional characterizations of the association and interactions between nucleophosmin-anaplastic lymphoma kinase and type I insulin-like growth factor receptor.

Shi B, Vishwamitra D, Granda JG, Whitton T, Shi P, Amin HM.

Neoplasia. 2013 Jun;15(6):669-83.

PMID:
23730215
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk