Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 79

1.

Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.

Roell MK, Issafras H, Bauer RJ, Michelson KS, Mendoza N, Vanegas SI, Gross LM, Larsen PD, Bedinger DH, Bohmann DJ, Nonet GH, Liu N, Lee SR, Handa M, Kantak SS, Horwitz AH, Hunter JJ, Owyang AM, Mirza AM, Corbin JA, White ML.

J Biol Chem. 2010 Jul 2;285(27):20607-14. doi: 10.1074/jbc.M110.115790. Epub 2010 Apr 21.

PMID:
20410301
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases.

Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L.

MAbs. 2011 Jan-Feb;3(1):49-60. Epub 2011 Jan 1.

PMID:
21048425
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1β antibody with differential receptor-modulating properties.

Issafras H, Corbin JA, Goldfine ID, Roell MK.

J Pharmacol Exp Ther. 2014 Jan;348(1):202-15. doi: 10.1124/jpet.113.205443. Epub 2013 Nov 5.

PMID:
24194526
[PubMed - indexed for MEDLINE]
4.

One target-two different binding modes: structural insights into gevokizumab and canakinumab interactions to interleukin-1β.

Blech M, Peter D, Fischer P, Bauer MM, Hafner M, Zeeb M, Nar H.

J Mol Biol. 2013 Jan 9;425(1):94-111. doi: 10.1016/j.jmb.2012.09.021. Epub 2012 Oct 3.

PMID:
23041424
[PubMed - indexed for MEDLINE]
6.

Cellular differentiation causes a selective down-regulation of interleukin (IL)-1beta-mediated NF-kappaB activation and IL-8 gene expression in intestinal epithelial cells.

Böcker U, Schottelius A, Watson JM, Holt L, Licato LL, Brenner DA, Sartor RB, Jobin C.

J Biol Chem. 2000 Apr 21;275(16):12207-13.

PMID:
10766857
[PubMed - indexed for MEDLINE]
Free Article
7.

Bradykinin B1 receptor up-regulation by interleukin-1beta and B1 agonist occurs through independent and synergistic intracellular signaling mechanisms in human lung fibroblasts.

Phagoo SB, Reddi K, Anderson KD, Leeb-Lundberg LM, Warburton D.

J Pharmacol Exp Ther. 2001 Jul;298(1):77-85.

PMID:
11408528
[PubMed - indexed for MEDLINE]
Free Article
8.

Interleukin-1-induced calcium flux in human fibroblasts is mediated through focal adhesions.

Arora PD, Ma J, Min W, Cruz T, McCulloch CA.

J Biol Chem. 1995 Mar 17;270(11):6042-9.

PMID:
7890736
[PubMed - indexed for MEDLINE]
Free Article
9.

Unmasking of LPA1 receptor-mediated migration response to lysophosphatidic acid by interleukin-1β-induced attenuation of Rho signaling pathways in rat astrocytes.

Sato K, Horiuchi Y, Jin Y, Malchinkhuu E, Komachi M, Kondo T, Okajima F.

J Neurochem. 2011 Apr;117(1):164-74. doi: 10.1111/j.1471-4159.2011.07188.x. Epub 2011 Feb 9.

PMID:
21244430
[PubMed - indexed for MEDLINE]
10.
11.

Interleukin-1-mediated febrile responses in mice and interleukin-1 beta activation of NFkappaB in mouse primary astrocytes, involves the interleukin-1 receptor accessory protein.

Zetterström M, Lundkvist J, Malinowsky D, Eriksson G, Bartfai T.

Eur Cytokine Netw. 1998 Jun;9(2):131-8.

PMID:
9681388
[PubMed - indexed for MEDLINE]
12.

Concordant and discordant interleukin-1-mediated signaling in lung fibroblast thy-1 subpopulations.

Hagood JS, Mangalwadi A, Guo B, MacEwen MW, Salazar L, Fuller GM.

Am J Respir Cell Mol Biol. 2002 Jun;26(6):702-8.

PMID:
12034569
[PubMed - indexed for MEDLINE]
13.

Interleukin-1 signaling in mouse astrocytes involves Akt: a study with interleukin-4 and IL-10.

Pousset F, Dantzer R, Kelley KW, Parnet P.

Eur Cytokine Netw. 2000 Sep;11(3):427-34.

PMID:
11022128
[PubMed - indexed for MEDLINE]
14.
15.

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways.

Fernandes A, Barateiro A, Falcão AS, Silva SL, Vaz AR, Brito MA, Silva RF, Brites D.

Glia. 2011 Jan;59(1):14-25. doi: 10.1002/glia.21072. Epub 2010 Oct 21.

PMID:
20967881
[PubMed - indexed for MEDLINE]
16.

Generation and characterization of rat anti-mouse ST2L monoclonal antibodies.

Fursov N, Johnston E, Duffy K, Cotty A, Petley T, Fisher J, Jiang H, Rycyzyn MA, Giles-Komar J, Powers G.

Hybridoma (Larchmt). 2011 Apr;30(2):153-62. doi: 10.1089/hyb.2010.0100.

PMID:
21529288
[PubMed - indexed for MEDLINE]
18.

Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblasts.

Pan ZK, Zuraw BL, Lung CC, Prossnitz ER, Browning DD, Ye RD.

J Clin Invest. 1996 Nov 1;98(9):2042-9.

PMID:
8903323
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mechanism of TNFalpha-induced IL-1alpha, IL-1beta and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones.

Turner NA, Mughal RS, Warburton P, O'Regan DJ, Ball SG, Porter KE.

Cardiovasc Res. 2007 Oct 1;76(1):81-90. Epub 2007 Jun 12.

PMID:
17612514
[PubMed - indexed for MEDLINE]
Free Article
20.

Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.

Granowitz EV, Saget BM, Wang MZ, Dinarello CA, Skolnik PR.

Mol Med. 1995 Sep;1(6):667-77.

PMID:
8529133
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk