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Results: 1 to 20 of 196

1.

MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2.

Foley NH, Bray IM, Tivnan A, Bryan K, Murphy DM, Buckley PG, Ryan J, O'Meara A, O'Sullivan M, Stallings RL.

Mol Cancer. 2010 Apr 21;9:83. doi: 10.1186/1476-4598-9-83.

PMID:
20409325
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma.

Buechner J, Tømte E, Haug BH, Henriksen JR, Løkke C, Flægstad T, Einvik C.

Br J Cancer. 2011 Jul 12;105(2):296-303. doi: 10.1038/bjc.2011.220. Epub 2011 Jun 7.

PMID:
21654684
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1.

Creevey L, Ryan J, Harvey H, Bray IM, Meehan M, Khan AR, Stallings RL.

Mol Cancer. 2013 Mar 26;12:23. doi: 10.1186/1476-4598-12-23.

PMID:
23531080
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma.

Haug BH, Henriksen JR, Buechner J, Geerts D, Tømte E, Kogner P, Martinsson T, Flægstad T, Sveinbjørnsson B, Einvik C.

Carcinogenesis. 2011 Jul;32(7):1005-12. doi: 10.1093/carcin/bgr073. Epub 2011 May 13.

PMID:
21572098
[PubMed - indexed for MEDLINE]
Free Article
5.

MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma.

Lovén J, Zinin N, Wahlström T, Müller I, Brodin P, Fredlund E, Ribacke U, Pivarcsi A, Påhlman S, Henriksson M.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1553-8. doi: 10.1073/pnas.0913517107. Epub 2010 Jan 4.

PMID:
20080637
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma.

Shohet JM, Ghosh R, Coarfa C, Ludwig A, Benham AL, Chen Z, Patterson DM, Barbieri E, Mestdagh P, Sikorski DN, Milosavljevic A, Kim ES, Gunaratne PH.

Cancer Res. 2011 Jun 1;71(11):3841-51. doi: 10.1158/0008-5472.CAN-10-4391. Epub 2011 Apr 15.

PMID:
21498633
[PubMed - indexed for MEDLINE]
Free Article
7.

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway.

Lynch J, Fay J, Meehan M, Bryan K, Watters KM, Murphy DM, Stallings RL.

Carcinogenesis. 2012 May;33(5):976-85. doi: 10.1093/carcin/bgs114. Epub 2012 Mar 1.

PMID:
22382496
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibition of cyclin-dependent kinase 1-induced cell death in neuroblastoma cells through the microRNA-34a-MYCN-survivin pathway.

Chen Y, Tsai YH, Tseng SH.

Surgery. 2013 Jan;153(1):4-16. doi: 10.1016/j.surg.2012.03.030. Epub 2012 Jun 15.

PMID:
22703967
[PubMed - indexed for MEDLINE]
9.

Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.

Torres J, Regan PL, Edo R, Leonhardt P, Jeng EI, Rappaport EF, Ikegaki N, Tang XX.

Int J Oncol. 2010 Oct;37(4):983-91.

PMID:
20811720
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis.

Chen Y, Stallings RL.

Cancer Res. 2007 Feb 1;67(3):976-83.

PMID:
17283129
[PubMed - indexed for MEDLINE]
Free Article
11.

Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival.

Bray I, Bryan K, Prenter S, Buckley PG, Foley NH, Murphy DM, Alcock L, Mestdagh P, Vandesompele J, Speleman F, London WB, McGrady PW, Higgins DG, O'Meara A, O'Sullivan M, Stallings RL.

PLoS One. 2009 Nov 16;4(11):e7850. doi: 10.1371/journal.pone.0007850.

PMID:
19924232
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo.

Chen Z, Lin Y, Barbieri E, Burlingame S, Hicks J, Ludwig A, Shohet JM.

Neoplasia. 2009 Aug;11(8):753-62.

PMID:
19649205
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The MYCN oncogene is a direct target of miR-34a.

Wei JS, Song YK, Durinck S, Chen QR, Cheuk AT, Tsang P, Zhang Q, Thiele CJ, Slack A, Shohet J, Khan J.

Oncogene. 2008 Sep 4;27(39):5204-13. doi: 10.1038/onc.2008.154. Epub 2008 May 26.

PMID:
18504438
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes.

Kumps C, Fieuw A, Mestdagh P, Menten B, Lefever S, Pattyn F, De Brouwer S, Sante T, Schulte JH, Schramm A, Van Roy N, Van Maerken T, Noguera R, Combaret V, Devalck C, Westermann F, Laureys G, Eggert A, Vandesompele J, De Preter K, Speleman F.

PLoS One. 2013;8(1):e52321. doi: 10.1371/journal.pone.0052321. Epub 2013 Jan 4.

PMID:
23308108
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models.

Wyce A, Ganji G, Smitheman KN, Chung CW, Korenchuk S, Bai Y, Barbash O, Le B, Craggs PD, McCabe MT, Kennedy-Wilson KM, Sanchez LV, Gosmini RL, Parr N, McHugh CF, Dhanak D, Prinjha RK, Auger KR, Tummino PJ.

PLoS One. 2013 Aug 23;8(8):e72967. doi: 10.1371/journal.pone.0072967. eCollection 2013.

PMID:
24009722
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase.

Veas-Perez de Tudela M, Delgado-Esteban M, Cuende J, Bolaños JP, Almeida A.

J Neurochem. 2010 May;113(4):819-25. doi: 10.1111/j.1471-4159.2010.06648.x. Epub 2010 Feb 17.

PMID:
20180881
[PubMed - indexed for MEDLINE]
17.

Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells.

Buechner J, Henriksen JR, Haug BH, Tømte E, Flaegstad T, Einvik C.

Differentiation. 2011 Jan;81(1):25-34. doi: 10.1016/j.diff.2010.09.184. Epub 2010 Oct 25.

PMID:
20980091
[PubMed - indexed for MEDLINE]
18.

MYCN regulates oncogenic MicroRNAs in neuroblastoma.

Schulte JH, Horn S, Otto T, Samans B, Heukamp LC, Eilers UC, Krause M, Astrahantseff K, Klein-Hitpass L, Buettner R, Schramm A, Christiansen H, Eilers M, Eggert A, Berwanger B.

Int J Cancer. 2008 Feb 1;122(3):699-704.

PMID:
17943719
[PubMed - indexed for MEDLINE]
19.

Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN.

Misawa A, Hosoi H, Tsuchiya K, Sugimoto T.

Int J Cancer. 2003 Mar 20;104(2):233-7.

PMID:
12569580
[PubMed - indexed for MEDLINE]
20.

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis.

Murphy DM, Buckley PG, Bryan K, Watters KM, Koster J, van Sluis P, Molenaar J, Versteeg R, Stallings RL.

Mol Carcinog. 2011 Jun;50(6):403-11. doi: 10.1002/mc.20722. Epub 2010 Dec 28.

PMID:
21557326
[PubMed - indexed for MEDLINE]
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