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Results: 1 to 20 of 146

1.

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.

Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A.

J Biol Chem. 2010 Jun 25;285(26):20252-61. doi: 10.1074/jbc.M109.089912. Epub 2010 Apr 20.

PMID:
20406818
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction.

Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha T, Hopfner KP, Jung JU.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16743-8. doi: 10.1073/pnas.0804947105. Epub 2008 Oct 23.

PMID:
18948594
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin.

Miranzo-Navarro D, Magor KE.

PLoS One. 2014 Jan 23;9(1):e86968. doi: 10.1371/journal.pone.0086968. eCollection 2014.

PMID:
24466302
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.

Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU.

Sci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577.

PMID:
24399297
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.

Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU.

Nature. 2007 Apr 19;446(7138):916-920.

PMID:
17392790
[PubMed - indexed for MEDLINE]
6.

Phosphorylation-mediated negative regulation of RIG-I antiviral activity.

Gack MU, Nistal-Villán E, Inn KS, García-Sastre A, Jung JU.

J Virol. 2010 Apr;84(7):3220-9. doi: 10.1128/JVI.02241-09. Epub 2010 Jan 13.

PMID:
20071582
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.

Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):17-28.

PMID:
16914100
[PubMed - indexed for MEDLINE]
8.

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors.

Castanier C, Zemirli N, Portier A, Garcin D, Bidère N, Vazquez A, Arnoult D.

BMC Biol. 2012 May 24;10:44. doi: 10.1186/1741-7007-10-44.

PMID:
22626058
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.

Lee Y, Song B, Park C, Kwon KS.

PLoS One. 2013 May 13;8(5):e63255. doi: 10.1371/journal.pone.0063255. Print 2013.

PMID:
23675467
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU.

PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29.

PMID:
23209422
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein.

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):168-72. doi: 10.1016/j.bbrc.2013.06.061. Epub 2013 Jun 26.

PMID:
23810392
[PubMed - indexed for MEDLINE]
12.

Structural and biochemical studies of RIG-I antiviral signaling.

Feng M, Ding Z, Xu L, Kong L, Wang W, Jiao S, Shi Z, Greene MI, Cong Y, Zhou Z.

Protein Cell. 2013 Feb;4(2):142-54. doi: 10.1007/s13238-012-2088-4. Epub 2012 Dec 20.

PMID:
23264040
[PubMed - indexed for MEDLINE]
13.

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus.

Mibayashi M, Martínez-Sobrido L, Loo YM, Cárdenas WB, Gale M Jr, García-Sastre A.

J Virol. 2007 Jan;81(2):514-24. Epub 2006 Nov 1.

PMID:
17079289
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses.

Oshiumi H, Miyashita M, Matsumoto M, Seya T.

PLoS Pathog. 2013;9(8):e1003533. doi: 10.1371/journal.ppat.1003533. Epub 2013 Aug 8.

PMID:
23950712
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection.

Oshiumi H, Matsumoto M, Hatakeyama S, Seya T.

J Biol Chem. 2009 Jan 9;284(2):807-17. doi: 10.1074/jbc.M804259200. Epub 2008 Nov 18.

PMID:
19017631
[PubMed - indexed for MEDLINE]
Free Article
16.

Functional characterization of domains of IPS-1 using an inducible oligomerization system.

Takamatsu S, Onoguchi K, Onomoto K, Narita R, Takahasi K, Ishidate F, Fujiwara TK, Yoneyama M, Kato H, Fujita T.

PLoS One. 2013;8(1):e53578. doi: 10.1371/journal.pone.0053578. Epub 2013 Jan 7.

PMID:
23308256
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.

Takaki H, Honda K, Atarashi K, Kobayashi F, Ebihara T, Oshiumi H, Matsumoto M, Shingai M, Seya T.

Mol Immunol. 2014 Feb;57(2):100-10. doi: 10.1016/j.molimm.2013.08.007. Epub 2013 Oct 4.

PMID:
24096085
[PubMed - indexed for MEDLINE]
18.

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.

Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A.

Cell Host Microbe. 2009 May 8;5(5):439-49. doi: 10.1016/j.chom.2009.04.006.

PMID:
19454348
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

PMID:
20127681
[PubMed - indexed for MEDLINE]
20.

Human bocavirus VP2 upregulates IFN-β pathway by inhibiting ring finger protein 125-mediated ubiquitination of retinoic acid-inducible gene-I.

Luo H, Zhang Z, Zheng Z, Ke X, Zhang X, Li Q, Liu Y, Bai B, Mao P, Hu Q, Wang H.

J Immunol. 2013 Jul 15;191(2):660-9. doi: 10.4049/jimmunol.1202933. Epub 2013 Jun 14.

PMID:
23772026
[PubMed - indexed for MEDLINE]
Free Article
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