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Items: 1 to 20 of 144

1.

SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor.

Xie Y, Rubenstein EM, Matt T, Hochstrasser M.

Genes Dev. 2010 May;24(9):893-903. doi: 10.1101/gad.1906510. Epub 2010 Apr 13.

2.

A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1.

Westerbeck JW, Pasupala N, Guillotte M, Szymanski E, Matson BC, Esteban C, Kerscher O.

Mol Biol Cell. 2014 Jan;25(1):1-16. doi: 10.1091/mbc.E13-05-0291. Epub 2013 Nov 6.

3.

SUMO-targeted ubiquitin ligases in genome stability.

Prudden J, Pebernard S, Raffa G, Slavin DA, Perry JJ, Tainer JA, McGowan CH, Boddy MN.

EMBO J. 2007 Sep 19;26(18):4089-101. Epub 2007 Aug 30.

4.

Quality control of a transcriptional regulator by SUMO-targeted degradation.

Wang Z, Prelich G.

Mol Cell Biol. 2009 Apr;29(7):1694-706. doi: 10.1128/MCB.01470-08. Epub 2009 Jan 12.

5.

Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates.

Mullen JR, Brill SJ.

J Biol Chem. 2008 Jul 18;283(29):19912-21. doi: 10.1074/jbc.M802690200. Epub 2008 May 22.

6.

STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites.

Hickey CM, Hochstrasser M.

Mol Biol Cell. 2015 Oct 1;26(19):3401-12. doi: 10.1091/mbc.E15-06-0436. Epub 2015 Aug 5.

7.

Ubiquitin-dependent proteolytic control of SUMO conjugates.

Uzunova K, Göttsche K, Miteva M, Weisshaar SR, Glanemann C, Schnellhardt M, Niessen M, Scheel H, Hofmann K, Johnson ES, Praefcke GJ, Dohmen RJ.

J Biol Chem. 2007 Nov 23;282(47):34167-75. Epub 2007 Aug 29.

8.

Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.

Böhm S, Mihalevic MJ, Casal MA, Bernstein KA.

DNA Repair (Amst). 2015 Feb;26:1-14. doi: 10.1016/j.dnarep.2014.12.004. Epub 2014 Dec 26.

9.

The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks.

Cook CE, Hochstrasser M, Kerscher O.

Cell Cycle. 2009 Apr 1;8(7):1080-9. Epub 2009 Apr 9.

10.

Concerted action of the ubiquitin-fusion degradation protein 1 (Ufd1) and Sumo-targeted ubiquitin ligases (STUbLs) in the DNA-damage response.

Køhler JB, Jørgensen ML, Beinoraité G, Thorsen M, Thon G.

PLoS One. 2013 Nov 12;8(11):e80442. doi: 10.1371/journal.pone.0080442. eCollection 2013.

11.

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response.

Poulsen SL, Hansen RK, Wagner SA, van Cuijk L, van Belle GJ, Streicher W, Wikström M, Choudhary C, Houtsmuller AB, Marteijn JA, Bekker-Jensen S, Mailand N.

J Cell Biol. 2013 Jun 10;201(6):797-807. doi: 10.1083/jcb.201212075.

12.

SIM-dependent enhancement of substrate-specific SUMOylation by a ubiquitin ligase in vitro.

Parker JL, Ulrich HD.

Biochem J. 2014 Feb 1;457(3):435-40. doi: 10.1042/BJ20131381.

PMID:
24224485
13.

The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation.

Xie Y, Kerscher O, Kroetz MB, McConchie HF, Sung P, Hochstrasser M.

J Biol Chem. 2007 Nov 23;282(47):34176-84. Epub 2007 Sep 11.

14.

A SIM-ultaneous role for SUMO and ubiquitin.

Perry JJ, Tainer JA, Boddy MN.

Trends Biochem Sci. 2008 May;33(5):201-8. doi: 10.1016/j.tibs.2008.02.001. Epub 2008 Apr 9. Review.

PMID:
18403209
15.

Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.

van de Pasch LA, Miles AJ, Nijenhuis W, Brabers NA, van Leenen D, Lijnzaad P, Brown MK, Ouellet J, Barral Y, Kops GJ, Holstege FC.

PLoS One. 2013 Jun 13;8(6):e65628. doi: 10.1371/journal.pone.0065628. Print 2013.

16.

Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45.

Sekiyama N, Arita K, Ikeda Y, Hashiguchi K, Ariyoshi M, Tochio H, Saitoh H, Shirakawa M.

Proteins. 2010 May 1;78(6):1491-502. doi: 10.1002/prot.22667.

PMID:
20077568
17.

Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA.

Yunus AA, Lima CD.

Mol Cell. 2009 Sep 11;35(5):669-82. doi: 10.1016/j.molcel.2009.07.013.

18.

Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.

Sun H, Leverson JD, Hunter T.

EMBO J. 2007 Sep 19;26(18):4102-12. Epub 2007 Aug 30.

19.

A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence.

Boutell C, Cuchet-Lourenço D, Vanni E, Orr A, Glass M, McFarlane S, Everett RD.

PLoS Pathog. 2011 Sep;7(9):e1002245. doi: 10.1371/journal.ppat.1002245. Epub 2011 Sep 15.

20.

Nuclear organization in genome stability: SUMO connections.

Nagai S, Davoodi N, Gasser SM.

Cell Res. 2011 Mar;21(3):474-85. doi: 10.1038/cr.2011.31. Epub 2011 Feb 15. Review.

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