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Results: 1 to 20 of 102

1.

Simple choline esters as potential anti-Alzheimer agents.

Alcaro S, Arcone R, Costa G, De Vita D, Iannone M, Ortuso F, Procopio A, Pasceri R, Rotiroti D, Scipione L.

Curr Pharm Des. 2010;16(6):692-7.

PMID:
20388079
[PubMed - indexed for MEDLINE]
2.

alpha,beta-Dehydrophenylalanine choline esters, a new class of reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase.

Grigoryan HA, Hambardzumyan AA, Mkrtchyan MV, Topuzyan VO, Halebyan GP, Asatryan RS.

Chem Biol Interact. 2008 Jan 10;171(1):108-16. Epub 2007 Sep 19.

PMID:
17980356
[PubMed - indexed for MEDLINE]
3.

Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats.

Rispoli V, Rotiroti D, Carelli V, Liberatore F, Scipione L, Marra R, Tortorella S, Di Rienzo B.

Pharmacol Biochem Behav. 2004 Aug;78(4):667-73.

PMID:
15301920
[PubMed - indexed for MEDLINE]
4.

Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles.

Samadi A, Marco-Contelles J, Soriano E, Alvarez-Pérez M, Chioua M, Romero A, González-Lafuente L, Gandía L, Roda JM, López MG, Villarroya M, García AG, Ríos Cde L.

Bioorg Med Chem. 2010 Aug 15;18(16):5861-72. doi: 10.1016/j.bmc.2010.06.095. Epub 2010 Jul 3.

PMID:
20656495
[PubMed - indexed for MEDLINE]
5.

Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease.

Geula C, Darvesh S.

Drugs Today (Barc). 2004 Aug;40(8):711-21. Review.

PMID:
15510242
[PubMed - indexed for MEDLINE]
6.

Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase.

Pacheco G, Palacios-Esquivel R, Moss DE.

J Pharmacol Exp Ther. 1995 Aug;274(2):767-70.

PMID:
7636741
[PubMed - indexed for MEDLINE]
7.

Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics.

Makhaeva GF, Aksinenko AY, Sokolov VB, Serebryakova OG, Richardson RJ.

Bioorg Med Chem Lett. 2009 Oct 1;19(19):5528-30. doi: 10.1016/j.bmcl.2009.08.065. Epub 2009 Aug 21.

PMID:
19717305
[PubMed - indexed for MEDLINE]
8.

[Inhibitory effects of sinapine on activity of acetylcholinesterase in cerebral homogenate and blood serum of rats].

He L, Li HT, Guo SW, Liu LF, Qiu JB, Li F, Cai BC.

Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(7):813-5. Chinese.

PMID:
18589789
[PubMed - indexed for MEDLINE]
9.

Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert.

Rispoli V, Rotiroti D, Carelli V, Liberatore F, Scipione L, Marra R, Giorgioni G, Di Stefano A.

Neurosci Lett. 2004 Feb 19;356(3):199-202.

PMID:
15036629
[PubMed - indexed for MEDLINE]
10.

Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer's disease.

Liston DR, Nielsen JA, Villalobos A, Chapin D, Jones SB, Hubbard ST, Shalaby IA, Ramirez A, Nason D, White WF.

Eur J Pharmacol. 2004 Feb 13;486(1):9-17.

PMID:
14751402
[PubMed - indexed for MEDLINE]
11.

Mechanism of hydrolysis of dicholine esters with long polymethylene chain by human butyrylcholinesterase.

Grigoryan H, Halebyan G, Lefebvre B, Brasme B, Masson P.

Biochim Biophys Acta. 2008 Nov;1784(11):1818-24. doi: 10.1016/j.bbapap.2008.08.005. Epub 2008 Aug 20.

PMID:
18778798
[PubMed - indexed for MEDLINE]
12.

Multiple binding sites involved in the effect of choline esters on decarbamoylation of monomethylcarbamoyl- or dimethylcarbamoly-acetylcholinesterase.

Sok DE, Kim YB, Choi SJ, Jung CH, Cha SH.

Biochem J. 1994 Aug 1;301 ( Pt 3):713-20.

PMID:
8053896
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeting acetylcholinesterase and butyrylcholinesterase in dementia.

Lane RM, Potkin SG, Enz A.

Int J Neuropsychopharmacol. 2006 Feb;9(1):101-24. Epub 2005 Aug 5. Review.

PMID:
16083515
[PubMed - indexed for MEDLINE]
14.

Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy.

Wilkinson DG, Francis PT, Schwam E, Payne-Parrish J.

Drugs Aging. 2004;21(7):453-78. Review.

PMID:
15132713
[PubMed - indexed for MEDLINE]
15.

Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons.

Darvesh S, Arora RC, Martin E, Magee D, Hopkins DA, Armour JA.

Exp Neurol. 2004 Aug;188(2):461-70.

PMID:
15246845
[PubMed - indexed for MEDLINE]
16.

Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives.

Rampa A, Bisi A, Belluti F, Gobbi S, Valenti P, Andrisano V, Cavrini V, Cavalli A, Recanatini M.

Bioorg Med Chem. 2000 Mar;8(3):497-506.

PMID:
10732965
[PubMed - indexed for MEDLINE]
17.

Choline pivaloyl ester strengthened the benefit effects of Tacrine and Galantamine on electroencephalographic and cognitive performances in nucleus basalis magnocellularis-lesioned and aged rats.

Rispoli V, Marra R, Costa N, Scipione L, Rotiroti D, De Vita D, Liberatore F, Carelli V.

Pharmacol Biochem Behav. 2006 Jul;84(3):453-67. Epub 2006 Jul 21.

PMID:
16859739
[PubMed - indexed for MEDLINE]
18.

Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease.

Martinez A, Castro A.

Expert Opin Investig Drugs. 2006 Jan;15(1):1-12. Review.

PMID:
16370929
[PubMed - indexed for MEDLINE]
19.

Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.

Arce MP, Rodríguez-Franco MI, González-Muñoz GC, Pérez C, López B, Villarroya M, López MG, García AG, Conde S.

J Med Chem. 2009 Nov 26;52(22):7249-57. doi: 10.1021/jm900628z.

PMID:
19856923
[PubMed - indexed for MEDLINE]
20.

Isosorbide-based cholinesterase inhibitors; replacement of 5-ester groups leading to increased stability.

Dillon GP, Gaynor JM, Khan D, Carolan CG, Ryder SA, Marquez JF, Reidy S, Gilmer JF.

Bioorg Med Chem. 2010 Feb;18(3):1045-53. doi: 10.1016/j.bmc.2009.12.052. Epub 2010 Jan 6.

PMID:
20093035
[PubMed - indexed for MEDLINE]

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