Similar articles for PMID: 20385867

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1

Natamycin inhibits vacuole fusion at the priming phase via a specific interaction with ergosterol.

te Welscher YM, Jones L, van Leeuwen MR, Dijksterhuis J, de Kruijff B, Eitzen G, Breukink E. te Welscher YM, et al. Antimicrob Agents Chemother. 2010 Jun;54(6):2618-25. doi: 10.1128/AAC.01794-09. Epub 2010 Apr 12. Antimicrob Agents Chemother. 2010. PMID: 20385867 Free PMC article.

2

Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane.

te Welscher YM, ten Napel HH, Balagué MM, Souza CM, Riezman H, de Kruijff B, Breukink E. te Welscher YM, et al. J Biol Chem. 2008 Mar 7;283(10):6393-401. doi: 10.1074/jbc.M707821200. Epub 2007 Dec 29. J Biol Chem. 2008. PMID: 18165687 Free article.

3

Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion.

Kato M, Wickner W. Kato M, et al. EMBO J. 2001 Aug 1;20(15):4035-40. doi: 10.1093/emboj/20.15.4035. EMBO J. 2001. PMID: 11483507 Free PMC article.

4

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast.

Szomek M, Reinholdt P, Walther HL, Scheidt HA, Müller P, Obermaier S, Poolman B, Kongsted J, Wüstner D. Szomek M, et al. Biochim Biophys Acta Biomembr. 2022 Nov 1;1864(11):184012. doi: 10.1016/j.bbamem.2022.184012. Epub 2022 Jul 29. Biochim Biophys Acta Biomembr. 2022. PMID: 35914570 Free article.

5

The polyene antimycotics nystatin and filipin disrupt the plasma membrane, whereas natamycin inhibits endocytosis in germinating conidia of Penicillium discolor.

Van Leeuwen MR, Golovina EA, Dijksterhuis J. Van Leeuwen MR, et al. J Appl Microbiol. 2009 Jun;106(6):1908-18. doi: 10.1111/j.1365-2672.2009.04165.x. Epub 2009 Feb 18. J Appl Microbiol. 2009. PMID: 19228256 Free article.

6

Targeted yeast vacuole disruption by polyene antibiotics with a macrocyclic lactone ring.

Ogita A, Fujita K, Usuki Y, Tanaka T. Ogita A, et al. Int J Antimicrob Agents. 2010 Jan;35(1):89-92. doi: 10.1016/j.ijantimicag.2009.08.014. Epub 2009 Nov 11. Int J Antimicrob Agents. 2010. PMID: 19910165

7

Freeze-fracture ultrastructural alterations induced by filipin, pimaricin, nystatin and amphotericin B in the plasmia membranes of Epidermophyton, Saccharomyces and red complex-induced membrane lesions.

Kitajima Y, Sekiya T, Nozawa Y. Kitajima Y, et al. Biochim Biophys Acta. 1976 Dec 2;455(2):452-65. doi: 10.1016/0005-2736(76)90317-5. Biochim Biophys Acta. 1976. PMID: 793632

8

Polyene antibiotic that inhibits membrane transport proteins.

te Welscher YM, van Leeuwen MR, de Kruijff B, Dijksterhuis J, Breukink E. te Welscher YM, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11156-9. doi: 10.1073/pnas.1203375109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733749 Free PMC article.

9

Molecular basis for fungicidal action of neothyonidioside, a triterpene glycoside from the sea cucumber, Australostichopus mollis.

Yibmantasiri P, Leahy DC, Busby BP, Angermayr SA, Sorgo AG, Boeger K, Heathcott R, Barber JM, Moraes G, Matthews JH, Northcote PT, Atkinson PH, Bellows DS. Yibmantasiri P, et al. Mol Biosyst. 2012 Mar;8(3):902-12. doi: 10.1039/c2mb05426d. Epub 2012 Jan 25. Mol Biosyst. 2012. PMID: 22271309

10

Visualization analysis of the vacuole-targeting fungicidal activity of amphotericin B against the parent strain and an ergosterol-less mutant of Saccharomyces cerevisiae.

Kang CK, Yamada K, Usuki Y, Ogita A, Fujita KI, Tanaka T. Kang CK, et al. Microbiology (Reading). 2013 May;159(Pt 5):939-947. doi: 10.1099/mic.0.065714-0. Epub 2013 Mar 8. Microbiology (Reading). 2013. PMID: 23475946 Free article.

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