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20382683,16503147,23783093,28411440,24616441,20082609,19887572,25676319,26264384,27050952,17100776,22278019,17003819,20546112,19828625,24408972,16945157,16424220,32070706,26659091,18310134,23288170,22017434,12794080,26808775,24636536,26907852,20068578,24652288,22081603,23469193,23077618,15611130,19109961,16762976,20955770,22394384,25537494,15885893,28103571,20189297,28585206,25022957,25092786,23750247,19629561,28639899,26224570,18817982,23443741,31515807,23873135,24056367,23106895,17299600,17981048,18025243,25826425,22850567,29038621,27786399,22314077,23918987,23957828,17124496,26924336,21893119,19018248,19895311,19963275,21697814,19778942,19398263,20739398,27098560,15120617,23775076,22082477,24947359,20578156,28585205,19147618,28382382,28934756,30576385,28585201,29333574,19201899,33000480,26012567,27653285,24467773,18923335,24416188,12787562,31181286,34542797,29143982,24840810,25564477,25539934,33221352,31679818,31885495,12496418,23462911,16526941,32053869,22366923,27040357,23127400,20358293,31541512,26228459,21788066,32512939,28620393,28809783,26446946,26016896,12445828,18404150,26721417,27888541,25682741,30038329,34716660,24444596,24599047,23417716,27026366,17981571,17485328,30472106,15385607,27339384,36841467,31441588,16267216,15353286,36214671,30270326,26300004,23478428,28698385,27634763,35222417,17917114,29251323,28636775,24416031,26493186,22438963,25714670,31677795,36916753,25270074,36321903,34718616,35729659,30620711,22851489,26829440,20385556,16046292,29706927,24293365,24493870,17485258,24872318,24478779,29679615,25809829,28612578,23539316,30228336,30466969,30009538,15469638,27630206,31528845,29526533,26714835,28781615,29201025,32526219,29977207,23320797,36626628,24478772,19289637,23748045,33991013,28744451,23150771,18483204,27465988,22977477,36339601,20678967,23117929,21913915,25504044,35932980,28351660,27710239,24705496,36980694,26871994,24297795,30344680,27389130,16150820,29130664,32542768,24244389,27584138,26020747,23935253,26844203,23975833,29428931,31871424,25344447,27049236,22637703,23037900,28938482,22545589,29690638,21777581,18235096,27338143,20157375,28425844,26663512,36449000,21400042,26614484,33732904,27259211,15056843,27445976,24692845,22429824,22649723,36709605,25881506,30710574,30081003,24361460,21266224,32707422,28641779,27374117,36469307,29149454,34576160,28864539,28100503,25518011,30894623,31363816,23667509,30066061,33758342,19187692,25781550,24550918,28455790,23466666,37048092,30218067,15930956,23351404,23576749,24281650,22745246,31360039,32413131,26332309,20699612,22893715,33494438,23221346,28910745,30301968,26916240,28592801,19050672,18567819,26275704,24273541,30549014,29743341,27171494,32449276,19543691,21852085,27781256,26054006,25776538,16496121,25938420,27980459,35674710,36502285,29250056,36575472,26655292,30566152,36551185,23059882,25852648,28518147,11027337,28399645,22449852,34829944,21633899,26061760,33183332,36468985,35898446,22192929,19439330,30804705,22002519,33637954,25926893,31415598,35321537,33017598,21593104,18728164,30403295,35055140,29042127,19017614,32979900,26167420,34728615,24106481,12166625,25470014,27617173,29522971,27281538,34571937,35227930,29768501,33597245,22511784,18206644,37108282,35811457,27994674,23269411,29285249,36716919,22836687,36766750,32808442,26412153,30137542,32629236,31413114,22039494,35215414,30198166,34182855,37072333,26258766,33132269,28607631,19228873,29326686,34736121,26697142,19913361,32283761,30619088,27077099,30439508,21372607,35363363,34905386,30531919,23590142,25599228,35262698,29657270,35765849,34556885,33658893,34440238,29721509,35393850,32591264,31569855,24853903,34603210,23179187,32759466,35752995,28811968,28337026,35978456,33633579,23022655,22891067,25666792,19897673,23991365,27617172,22675238,34923751,25926797,22373492,25173803,25784914,26638118,26486919,21625100,37085918,24409182,33706888,29507613,33440913,31670115,28622517,35358473,36139371,1733120,26294433,30082376,36496995,19343616,22400114,33114725,34572917,28367476,31624681,23277002,21605069,32300052,19668101,36670988,33116712,24575375,26294424,34327017,22717452,27419143,36726688,30119990,32796940,27774476,22411577,3583293,25964776,28275368,31592625,33931522,28898999,25830526[uid]

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Tumor necrosis-like weak inducer of apoptosis as a proinflammatory cytokine in human adipocyte cells: up-regulation in severe obesity is mediated by inflammation but not hypoxia.

Vendrell J, Maymó-Masip E, Tinahones F, García-España A, Megia A, Caubet E, García-Fuentes E, Chacón MR. Vendrell J, et al. J Clin Endocrinol Metab. 2010 Jun;95(6):2983-92. doi: 10.1210/jc.2009-2481. Epub 2010 Apr 9. J Clin Endocrinol Metab. 2010. PMID: 20382683 Free article.

Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity.

Chacón MR, Richart C, Gómez JM, Megía A, Vilarrasa N, Fernández-Real JM, García-España A, Miranda M, Masdevall C, Ricard W, Caubet E, Soler J, Vendrell J. Chacón MR, et al. Cytokine. 2006 Feb 7;33(3):129-37. doi: 10.1016/j.cyto.2005.12.005. Epub 2006 Feb 28. Cytokine. 2006. PMID: 16503147

The rise of soluble TWEAK levels in severely obese subjects after bariatric surgery may affect adipocyte-cytokine production induced by TNFα.

Maymó-Masip E, Fernández-Veledo S, Garcia España A, Vázquez-Carballo A, Tinahones FJ, García-Fuentes E, Garrifo-Sanchez L, Rodriguez Mdel M, Vendrell J, Chacón MR. Maymó-Masip E, et al. J Clin Endocrinol Metab. 2013 Aug;98(8):E1323-33. doi: 10.1210/jc.2012-4177. Epub 2013 Jun 19. J Clin Endocrinol Metab. 2013. PMID: 23783093 Free article.

TWEAK/Fn14 promotes pro-inflammatory cytokine secretion in hepatic stellate cells via NF-κB/STAT3 pathways.

Wang A, Zhang F, Xu H, Xu M, Cao Y, Wang C, Xu Y, Su M, Zhang M, Zhuge Y. Wang A, et al. Mol Immunol. 2017 Jul;87:67-75. doi: 10.1016/j.molimm.2017.04.003. Epub 2017 Apr 12. Mol Immunol. 2017. PMID: 28411440

Deletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity.

Bennett G, Strissel KJ, DeFuria J, Wang J, Wu D, Burkly LC, Obin MS. Bennett G, et al. Obesity (Silver Spring). 2014 Jun;22(6):1485-94. doi: 10.1002/oby.20726. Epub 2014 Mar 8. Obesity (Silver Spring). 2014. PMID: 24616441 Free PMC article.

Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.

Mustonen E, Säkkinen H, Tokola H, Isopoussu E, Aro J, Leskinen H, Ruskoaho H, Rysä J. Mustonen E, et al. Acta Physiol (Oxf). 2010 May;199(1):11-22. doi: 10.1111/j.1748-1716.2010.02080.x. Epub 2010 Jan 16. Acta Physiol (Oxf). 2010. PMID: 20082609

Effects of TWEAK (TNF superfamily member 12) on differentiation, metabolism, and secretory function of human primary preadipocytes and adipocytes.

Tiller G, Fischer-Posovszky P, Laumen H, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H. Tiller G, et al. Endocrinology. 2009 Dec;150(12):5373-83. doi: 10.1210/en.2009-0488. Epub 2009 Nov 3. Endocrinology. 2009. PMID: 19887572

The tumor necrosis factor superfamily members TWEAK, TNFSF15 and fibroblast growth factor-inducible protein 14 are upregulated in proliferative diabetic retinopathy.

Abu El-Asrar AM, De Hertogh G, Nawaz MI, Siddiquei MM, Van den Eynde K, Mohammad G, Opdenakker G, Geboes K. Abu El-Asrar AM, et al. Ophthalmic Res. 2015;53(3):122-30. doi: 10.1159/000369300. Epub 2015 Feb 7. Ophthalmic Res. 2015. PMID: 25676319 Free article.

TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation.

Cheng H, Xu M, Liu X, Zou X, Zhan N, Xia Y. Cheng H, et al. Exp Dermatol. 2016 Jan;25(1):32-7. doi: 10.1111/exd.12820. Epub 2015 Sep 15. Exp Dermatol. 2016. PMID: 26264384

Tumor necrosis factor-like weak inducer of apoptosis association with proliferative diabetic retinopathy and promotes proliferation and collagen synthesis in retinal ARPE-19 cells.

Chen DY, Su GF. Chen DY, et al. Genet Mol Res. 2016 Mar 18;15(1). doi: 10.4238/gmr.15016920. Genet Mol Res. 2016. PMID: 27050952 Free article.

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