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Items: 1 to 20 of 148

1.

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.

Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):352-60. doi: 10.1016/j.taap.2010.04.001. Epub 2010 Apr 9.

2.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.

3.

Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Dec 1;249(2):178-87. doi: 10.1016/j.taap.2010.09.005. Epub 2010 Sep 16.

4.

Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2011 Jun 1;253(2):112-20. doi: 10.1016/j.taap.2011.03.015. Epub 2011 Mar 30.

5.

UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells.

Black AT, Gordon MK, Heck DE, Gallo MA, Laskin DL, Laskin JD.

Biochem Pharmacol. 2011 Apr 1;81(7):873-80. doi: 10.1016/j.bcp.2011.01.014. Epub 2011 Feb 1.

6.

Cytokine regulation by MAPK activated kinase 2 in keratinocytes exposed to sulfur mustard.

Yego EC, Dillman JF 3rd.

Toxicol In Vitro. 2013 Oct;27(7):2067-75. doi: 10.1016/j.tiv.2013.07.002. Epub 2013 Jul 10.

PMID:
23851002
7.

Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.

Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 May 15;261(1):22-30. doi: 10.1016/j.taap.2012.03.004. Epub 2012 Mar 14.

8.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

9.

Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):245-55. doi: 10.1016/j.taap.2010.10.027. Epub 2010 Nov 9.

10.

Effects of CEES and LPS synergistically stimulate oxidative stress inactivates OGG1 signaling in macrophage cells.

Sagar S, Kumar P, Behera RR, Pal A.

J Hazard Mater. 2014 Aug 15;278:236-49. doi: 10.1016/j.jhazmat.2014.05.096. Epub 2014 Jun 6.

PMID:
24976129
11.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ.

Free Radic Biol Med. 2014 Jul;72:285-95. doi: 10.1016/j.freeradbiomed.2014.04.022. Epub 2014 May 9.

12.

Ameliorating effect of S-2(ω-aminoalkylamino) alkylaryl sulfide (DRDE-07) on sulfur mustard analogue, 2-chloroethyl ethyl sulfide-induced oxidative stress and inflammation.

Sawale SD, Ambhore PD, Pawar PP, Pathak U, Deb U, Satpute RM.

Toxicol Mech Methods. 2013 Nov;23(9):702-10. doi: 10.3109/15376516.2013.843109. Epub 2013 Oct 28.

PMID:
24024669
13.

Immunochemical analysis of poly(ADP-ribosyl)ation in HaCaT keratinocytes induced by the mono-alkylating agent 2-chloroethyl ethyl sulfide (CEES): Impact of experimental conditions.

Debiak M, Lex K, Ponath V, Burckhardt-Boer W, Thiermann H, Steinritz D, Schmidt A, Mangerich A, Bürkle A.

Toxicol Lett. 2016 Feb 26;244:72-80. doi: 10.1016/j.toxlet.2015.09.009. Epub 2015 Sep 14.

PMID:
26383632
14.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

O'Neill HC, White CW, Veress LA, Hendry-Hofer TB, Loader JE, Min E, Huang J, Rancourt RC, Day BJ.

Free Radic Biol Med. 2010 May 1;48(9):1188-96. doi: 10.1016/j.freeradbiomed.2010.01.039. Epub 2010 Feb 4.

15.

Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.

Paromov V, Brannon M, Kumari S, Samala M, Qui M, Smith M, Stone WL.

Int J Toxicol. 2011 Mar;30(2):197-206. doi: 10.1177/1091581810390824. Epub 2011 Feb 7.

PMID:
21300769
16.

Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.

Pal A, Tewari-Singh N, Gu M, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

Free Radic Biol Med. 2009 Dec 1;47(11):1640-51. doi: 10.1016/j.freeradbiomed.2009.09.011. Epub 2009 Sep 15.

17.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R.

Toxicol Sci. 2009 Mar;108(1):194-206. doi: 10.1093/toxsci/kfn261. Epub 2008 Dec 15.

18.

Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.

Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):176-83. doi: 10.1016/j.taap.2011.06.012. Epub 2011 Jun 23.

PMID:
21723306
19.

Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.

Blaha M, Bowers W Jr, Kohl J, DuBose D, Walker J.

In Vitr Mol Toxicol. 2000 Summer;13(2):99-111.

PMID:
11031321
20.

UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes.

Black AT, Gray JP, Shakarjian MP, Mishin V, Laskin DL, Heck DE, Laskin JD.

Toxicol Appl Pharmacol. 2008 Oct 1;232(1):14-24. doi: 10.1016/j.taap.2008.05.017. Epub 2008 May 28.

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