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Ugeskr Laeger. 2010 Jan 4;172(1):41-3.

[SPECT combined with CT angiography yield better diagnostic accuracy of pulmonary embolism--secondary publication].

[Article in Danish]

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  • 1Klinik for Klinisk Fysiologi, Nuklear Medicin & PET, Rigshospitalet, DK-2100 Kobenhavn Ø, Denmark.


The aim of our study was to perform a prospective study that compared the diagnostic ability of V/Q single photon emission computer tomography (V/Q-SPECT), V/Q-SPECT combined with low-dose computed tomography (CT) and pulmonary multidetector computed tomography(MDCT)-angiography in patients suspected of having pulmonary embolism (PE) using a dedicated combined SPECT/MDCT-scanner. V/Q-SPECT in combination with low-dose CT had a sensitivity of 97% and a specificity of 100%. MDCT angiography had a sensitivity of 68% and a specificity of 100%. We conclude that V/Q-SPECT in combination with low-dose CT without contrast has an excellent diagnostic performance and should be considered the first-line imaging technique in the work-up of PE in most cases.

[PubMed - indexed for MEDLINE]
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