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Results: 1 to 20 of 95

1.

p53-mediated hematopoietic stem and progenitor cell competition.

Bondar T, Medzhitov R.

Cell Stem Cell. 2010 Apr 2;6(4):309-22. doi: 10.1016/j.stem.2010.03.002.

PMID:
20362536
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Irradiation selects for p53-deficient hematopoietic progenitors.

Marusyk A, Porter CC, Zaberezhnyy V, DeGregori J.

PLoS Biol. 2010 Mar 2;8(3):e1000324. doi: 10.1371/journal.pbio.1000324.

PMID:
20208998
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

Milyavsky M, Gan OI, Trottier M, Komosa M, Tabach O, Notta F, Lechman E, Hermans KG, Eppert K, Konovalova Z, Ornatsky O, Domany E, Meyn MS, Dick JE.

Cell Stem Cell. 2010 Aug 6;7(2):186-97. doi: 10.1016/j.stem.2010.05.016. Epub 2010 Jul 8.

PMID:
20619763
[PubMed - indexed for MEDLINE]
Free Article
4.

Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells.

Meng A, Wang Y, Van Zant G, Zhou D.

Cancer Res. 2003 Sep 1;63(17):5414-9.

PMID:
14500376
[PubMed - indexed for MEDLINE]
Free Article
5.

Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.

Hinkal GW, Gatza CE, Parikh N, Donehower LA.

Mech Ageing Dev. 2009 Apr;130(4):262-71.

PMID:
19396980
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The ATM/p53/p21 pathway influences cell fate decision between apoptosis and senescence in reoxygenated hematopoietic progenitor cells.

Zhang X, Li J, Sejas DP, Pang Q.

J Biol Chem. 2005 May 20;280(20):19635-40. Epub 2005 Mar 7.

PMID:
15753076
[PubMed - indexed for MEDLINE]
Free Article
7.

Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence.

Feng L, Hollstein M, Xu Y.

Cell Cycle. 2006 Dec;5(23):2812-9. Epub 2006 Dec 1.

PMID:
17172844
[PubMed - indexed for MEDLINE]
Free Article
8.

Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity.

Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM.

Genes Dev. 2011 Jul 1;25(13):1426-38. doi: 10.1101/gad.2024411.

PMID:
21724834
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.

Singh SK, Williams CA, Klarmann K, Burkett SS, Keller JR, Oberdoerffer P.

J Exp Med. 2013 May 6;210(5):987-1001. doi: 10.1084/jem.20121608. Epub 2013 Apr 29.

PMID:
23630229
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma.

Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM, Look AT.

Cell. 2005 Nov 18;123(4):641-53.

PMID:
16286009
[PubMed - indexed for MEDLINE]
Free Article
11.

The p53 tumor suppressor protein regulates hematopoietic stem cell fate.

Asai T, Liu Y, Bae N, Nimer SD.

J Cell Physiol. 2011 Sep;226(9):2215-21. doi: 10.1002/jcp.22561. Review.

PMID:
21660944
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells.

Asai T, Liu Y, Di Giandomenico S, Bae N, Ndiaye-Lobry D, Deblasio A, Menendez S, Antipin Y, Reva B, Wevrick R, Nimer SD.

Blood. 2012 Aug 23;120(8):1601-12. doi: 10.1182/blood-2011-11-393983. Epub 2012 Jul 9.

PMID:
22776820
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells.

Cuddihy AR, Jalali F, Coackley C, Bristow RG.

Mol Cancer Ther. 2008 Apr;7(4):980-92. doi: 10.1158/1535-7163.MCT-07-0471.

PMID:
18413811
[PubMed - indexed for MEDLINE]
Free Article
14.

The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior.

Liu Y, Elf SE, Asai T, Miyata Y, Liu Y, Sashida G, Huang G, Di Giandomenico S, Koff A, Nimer SD.

Cell Cycle. 2009 Oct 1;8(19):3120-4. Review.

PMID:
19755852
[PubMed - indexed for MEDLINE]
Free Article
15.

Hematopoietic stem cell quiescence: yet another role for p53.

van Os R, de Haan G, Dykstra BJ.

Cell Stem Cell. 2009 Jan 9;4(1):7-8. doi: 10.1016/j.stem.2008.12.007.

PMID:
19128788
[PubMed - indexed for MEDLINE]
Free Article
16.

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis.

Mohrin M, Bourke E, Alexander D, Warr MR, Barry-Holson K, Le Beau MM, Morrison CG, Passegué E.

Cell Stem Cell. 2010 Aug 6;7(2):174-85. doi: 10.1016/j.stem.2010.06.014. Epub 2010 Jul 8.

PMID:
20619762
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

p53-dependent gene profiling for reactive oxygen species after benzene inhalation: special reference to genes associated with cell cycle regulation.

Hirabayashi Y.

Chem Biol Interact. 2005 May 30;153-154:165-70. Epub 2005 Apr 22. Review.

PMID:
15935813
[PubMed - indexed for MEDLINE]
18.

Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence.

Tavana O, Benjamin CL, Puebla-Osorio N, Sang M, Ullrich SE, Ananthaswamy HN, Zhu C.

Cell Cycle. 2010 Aug 15;9(16):3328-36. doi: 10.4161/cc.9.16.12688. Epub 2010 Aug 16.

PMID:
20703098
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Notch1 activation reduces proliferation in the multipotent hematopoietic progenitor cell line FDCP-mix through a p53-dependent pathway but Notch1 effects on myeloid and erythroid differentiation are independent of p53.

Henning K, Heering J, Schwanbeck R, Schroeder T, Helmbold H, Schäfer H, Deppert W, Kim E, Just U.

Cell Death Differ. 2008 Feb;15(2):398-407. Epub 2007 Nov 30.

PMID:
18049480
[PubMed - indexed for MEDLINE]
Free Article
20.

Gamma-ray-induced cell killing and chromosome abnormalities in the bone marrow of p53-deficient mice.

Wang L, Cui Y, Lord BI, Roberts SA, Potten CS, Hendry JH, Scott D.

Radiat Res. 1996 Sep;146(3):259-66.

PMID:
8752303
[PubMed - indexed for MEDLINE]

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