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Items: 1 to 20 of 113

1.

Use of transcriptomics in understanding mechanisms of drug-induced toxicity.

Cui Y, Paules RS.

Pharmacogenomics. 2010 Apr;11(4):573-85. doi: 10.2217/pgs.10.37. Review.

2.

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.

Blomme EA, Yang Y, Waring JF.

Toxicol Lett. 2009 Apr 10;186(1):22-31. doi: 10.1016/j.toxlet.2008.09.017. Epub 2008 Oct 17. Review.

PMID:
18996174
3.

Systems toxicology used in nanotoxicology: mechanistic insights into the hepatotoxicity of nano-copper particles from toxicogenomics.

Yang B, Wang Q, Lei R, Wu C, Shi C, Wang Q, Yuan Y, Wang Y, Luo Y, Hu Z, Ma H, Liao M.

J Nanosci Nanotechnol. 2010 Dec;10(12):8527-37.

PMID:
21121362
4.

Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.

Laifenfeld D, Qiu L, Swiss R, Park J, Macoritto M, Will Y, Younis HS, Lawton M.

Toxicol Sci. 2014 Jan;137(1):234-48. doi: 10.1093/toxsci/kft232. Epub 2013 Oct 17.

5.

Blood transcriptomics: applications in toxicology.

Joseph P, Umbright C, Sellamuthu R.

J Appl Toxicol. 2013 Nov;33(11):1193-202. doi: 10.1002/jat.2861. Epub 2013 Mar 1. Review.

6.

Toxicogenomics strategies for predicting drug toxicity.

Martin R, Rose D, Yu K, Barros S.

Pharmacogenomics. 2006 Oct;7(7):1003-16.

PMID:
17054411
7.

The introduction of toxicogenomics; potential new markers of hepatotoxicity.

Heijne WH, Stierum RH, Leeman WR, van Ommen B.

Cancer Biomark. 2005;1(1):41-57. Review. No abstract available.

PMID:
17192031
8.

Toxicogenomics and metabolomics of pentamethylchromanol (PMCol)-induced hepatotoxicity.

Parman T, Bunin DI, Ng HH, McDunn JE, Wulff JE, Wang A, Swezey R, Rasay L, Fairchild DG, Kapetanovic IM, Green CE.

Toxicol Sci. 2011 Dec;124(2):487-501. doi: 10.1093/toxsci/kfr238. Epub 2011 Sep 13.

9.

In vitro transcriptomic prediction of hepatotoxicity for early drug discovery.

Cheng F, Theodorescu D, Schulman IG, Lee JK.

J Theor Biol. 2011 Dec 7;290:27-36. doi: 10.1016/j.jtbi.2011.08.009. Epub 2011 Aug 27.

10.

Toxicogenomics in predictive toxicology in drug development.

Suter L, Babiss LE, Wheeldon EB.

Chem Biol. 2004 Feb;11(2):161-71. Review.

11.

Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity.

Harrill AH, Rusyn I.

Expert Opin Drug Metab Toxicol. 2008 Nov;4(11):1379-89. doi: 10.1517/17425255.4.11.1379 . Review.

12.

Genomic-based biomarkers of drug-induced nephrotoxicity.

Davis JW, Kramer JA.

Expert Opin Drug Metab Toxicol. 2006 Feb;2(1):95-101. Review.

PMID:
16863471
13.

Toxicogenetics: population-based testing of drug and chemical safety in mouse models.

Rusyn I, Gatti DM, Wiltshire T, Kleeberger SR, Threadgill DW.

Pharmacogenomics. 2010 Aug;11(8):1127-36. doi: 10.2217/pgs.10.100. Review. Erratum in: Pharmacogenomics. 2010 Sep;11(9):1344. Wilshire, Timothy [corrected to Wiltshire, Timothy].

14.
15.

Toxicogenomic analysis methods for predictive toxicology.

Maggioli J, Hoover A, Weng L.

J Pharmacol Toxicol Methods. 2006 Jan-Feb;53(1):31-7. Epub 2005 Oct 19. Review.

PMID:
16236530
16.

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Kienhuis AS, Bessems JG, Pennings JL, Driessen M, Luijten M, van Delft JH, Peijnenburg AA, van der Ven LT.

Toxicol Appl Pharmacol. 2011 Jan 15;250(2):96-107. doi: 10.1016/j.taap.2010.10.013. Epub 2010 Oct 21. Review.

PMID:
20970440
17.

Genomic and proteomic approaches for predicting toxicity and adverse drug reactions.

Ge F, He QY.

Expert Opin Drug Metab Toxicol. 2009 Jan;5(1):29-37. doi: 10.1517/17425250802661895 . Review.

PMID:
19236227
18.

Genetic characterization to improve interpretation and clinical management of hepatotoxicity caused by tyrosine kinase inhibitors.

Spraggs CF, Xu CF, Hunt CM.

Pharmacogenomics. 2013 Apr;14(5):541-54. doi: 10.2217/pgs.13.24. Review.

PMID:
23556451
19.

Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.

Hanafusa H, Morikawa Y, Uehara T, Kaneto M, Ono A, Yamada H, Ohno Y, Urushidani T.

Toxicology. 2014 Oct 3;324:43-54. doi: 10.1016/j.tox.2014.07.005. Epub 2014 Jul 19.

PMID:
25051504
20.

Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology.

Heijne WH, Kienhuis AS, van Ommen B, Stierum RH, Groten JP.

Expert Rev Proteomics. 2005 Oct;2(5):767-80. Review.

PMID:
16209655
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