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Results: 1 to 20 of 146

1.

Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study.

Ruilope LM, Dukat A, Böhm M, Lacourcière Y, Gong J, Lefkowitz MP.

Lancet. 2010 Apr 10;375(9722):1255-66. doi: 10.1016/S0140-6736(09)61966-8. Epub 2010 Mar 16.

PMID:
20236700
[PubMed - indexed for MEDLINE]
2.

Efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Asian patients with hypertension: a randomized, double-blind, placebo-controlled study.

Kario K, Sun N, Chiang FT, Supasyndh O, Baek SH, Inubushi-Molessa A, Zhang Y, Gotou H, Lefkowitz M, Zhang J.

Hypertension. 2014 Apr;63(4):698-705. doi: 10.1161/HYPERTENSIONAHA.113.02002. Epub 2014 Jan 20.

PMID:
24446062
[PubMed - indexed for MEDLINE]
3.

The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial.

Solomon SD, Zile M, Pieske B, Voors A, Shah A, Kraigher-Krainer E, Shi V, Bransford T, Takeuchi M, Gong J, Lefkowitz M, Packer M, McMurray JJ; Prospective comparison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion (PARAMOUNT) Investigators.

Lancet. 2012 Oct 20;380(9851):1387-95. doi: 10.1016/S0140-6736(12)61227-6. Epub 2012 Aug 26.

PMID:
22932717
[PubMed - indexed for MEDLINE]
4.

Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study.

Giles TD, Weber MA, Basile J, Gradman AH, Bharucha DB, Chen W, Pattathil M; NAC-MD-01 Study Investigators.

Lancet. 2014 May 31;383(9932):1889-98. doi: 10.1016/S0140-6736(14)60614-0.

PMID:
24881993
[PubMed - indexed for MEDLINE]
5.

Blood-pressure reduction with LCZ696.

Waeber B, Feihl F.

Lancet. 2010 Apr 10;375(9722):1228-9. doi: 10.1016/S0140-6736(10)60363-7. Epub 2010 Mar 16. No abstract available.

PMID:
20236699
[PubMed - indexed for MEDLINE]
6.
7.
8.

Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial.

Solomon SD, Janardhanan R, Verma A, Bourgoun M, Daley WL, Purkayastha D, Lacourcière Y, Hippler SE, Fields H, Naqvi TZ, Mulvagh SL, Arnold JM, Thomas JD, Zile MR, Aurigemma GP; Valsartan In Diastolic Dysfunction (VALIDD) Investigators.

Lancet. 2007 Jun 23;369(9579):2079-87.

PMID:
17586303
[PubMed - indexed for MEDLINE]
9.

Dose-response efficacy of valsartan, a new angiotensin II receptor blocker.

Pool JL, Glazer R, Chiang YT, Gatlin M.

J Hum Hypertens. 1999 Apr;13(4):275-81.

PMID:
10333347
[PubMed - indexed for MEDLINE]
10.

Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial.

Oparil S, Yarows SA, Patel S, Fang H, Zhang J, Satlin A.

Lancet. 2007 Jul 21;370(9583):221-9. Erratum in: Lancet. 2007 Nov 3;370(9598):1542.

PMID:
17658393
[PubMed - indexed for MEDLINE]
12.

Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).

Gu J, Noe A, Chandra P, Al-Fayoumi S, Ligueros-Saylan M, Sarangapani R, Maahs S, Ksander G, Rigel DF, Jeng AY, Lin TH, Zheng W, Dole WP.

J Clin Pharmacol. 2010 Apr;50(4):401-14. doi: 10.1177/0091270009343932. Epub 2009 Nov 23.

PMID:
19934029
[PubMed - indexed for MEDLINE]
13.

Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.

Everett BM, Glynn RJ, Danielson E, Ridker PM; Val-MARC Investigators.

Clin Ther. 2008 Apr;30(4):661-72.

PMID:
18498915
[PubMed - indexed for MEDLINE]
14.

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril.

Black HR, Graff A, Shute D, Stoltz R, Ruff D, Levine J, Shi Y, Mallows S.

J Hum Hypertens. 1997 Aug;11(8):483-9.

PMID:
9322828
[PubMed - indexed for MEDLINE]
15.

Comparison of valsartan 160 mg with lisinopril 20 mg, given as monotherapy or in combination with a diuretic, for the treatment of hypertension: the Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril (PREVAIL) study.

Malacco E, Santonastaso M, Varì NA, Gargiulo A, Spagnuolo V, Bertocchi F, Palatini P; Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril Study.

Clin Ther. 2004 Jun;26(6):855-65. Erratum in: Clin Ther. 2004 Jul;26(7):1185. Clin Ther. 2005 Jan;27(1):142.

PMID:
15262456
[PubMed - indexed for MEDLINE]
16.

Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately controlled by valsartan 320 mg monotherapy.

Tuomilehto J, Tykarski A, Baumgart P, Reimund B, Le Breton S, Ferber P.

Blood Press Suppl. 2008 Jun;1:15-23.

PMID:
18705531
[PubMed - indexed for MEDLINE]
17.

Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: data from a multicenter, randomized, double-blind, 12-week trial.

Elliott WJ, Calhoun DA, DeLucca PT, Gazdick LP, Kerns DE, Zeldin RK.

Clin Ther. 2001 Aug;23(8):1166-79.

PMID:
11558856
[PubMed - indexed for MEDLINE]
18.

Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients with stage 2 hypertension.

Poldermans D, Glazes R, Kargiannis S, Wernsing M, Kaczor J, Chiang YT, Yen J, Gamboa R, Fomina I.

Clin Ther. 2007 Feb;29(2):279-89.

PMID:
17472820
[PubMed - indexed for MEDLINE]
20.

Effects of the angiotensin receptor blocker azilsartan medoxomil versus olmesartan and valsartan on ambulatory and clinic blood pressure in patients with stages 1 and 2 hypertension.

White WB, Weber MA, Sica D, Bakris GL, Perez A, Cao C, Kupfer S.

Hypertension. 2011 Mar;57(3):413-20. doi: 10.1161/HYPERTENSIONAHA.110.163402. Epub 2011 Jan 31.

PMID:
21282560
[PubMed - indexed for MEDLINE]
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