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Results: 1 to 20 of 345

1.

Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation.

Goodwin CR, Lal B, Zhou X, Ho S, Xia S, Taeger A, Murray J, Laterra J.

Cancer Res. 2010 Apr 1;70(7):2932-41. doi: 10.1158/0008-5472.CAN-09-3570. Epub 2010 Mar 16.

PMID:
20233866
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PTEN reconstitution alters glioma responses to c-Met pathway inhibition.

Goodwin CR, Lal B, Ho S, Woodard CL, Zhou X, Taeger A, Xia S, Laterra J.

Anticancer Drugs. 2011 Oct;22(9):905-12. doi: 10.1097/CAD.0b013e3283484750.

PMID:
21654317
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors.

Burgess T, Coxon A, Meyer S, Sun J, Rex K, Tsuruda T, Chen Q, Ho SY, Li L, Kaufman S, McDorman K, Cattley RC, Sun J, Elliott G, Zhang K, Feng X, Jia XC, Green L, Radinsky R, Kendall R.

Cancer Res. 2006 Feb 1;66(3):1721-9. Erratum in: Cancer Res. 2006 Jun 1;66(11):5976.

PMID:
16452232
[PubMed - indexed for MEDLINE]
Free Article
4.

EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.

Lal B, Goodwin CR, Sang Y, Foss CA, Cornet K, Muzamil S, Pomper MG, Kim J, Laterra J.

Mol Cancer Ther. 2009 Jul;8(7):1751-60. doi: 10.1158/1535-7163.MCT-09-0188. Epub 2009 Jul 7.

PMID:
19584231
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mechanisms of hepatocyte growth factor-induced retinal endothelial cell migration and growth.

Cai W, Rook SL, Jiang ZY, Takahara N, Aiello LP.

Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1885-93.

PMID:
10845613
[PubMed - indexed for MEDLINE]
Free Article
6.

Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation.

Lal B, Xia S, Abounader R, Laterra J.

Clin Cancer Res. 2005 Jun 15;11(12):4479-86.

PMID:
15958633
[PubMed - indexed for MEDLINE]
Free Article
7.

Soluble c-Met receptors inhibit phosphorylation of c-Met and growth of hepatocyte growth factor: c-Met-dependent tumors in animal models.

Coxon A, Rex K, Meyer S, Sun J, Sun J, Chen Q, Radinsky R, Kendall R, Burgess TL.

Mol Cancer Ther. 2009 May;8(5):1119-25. doi: 10.1158/1535-7163.MCT-08-1032. Epub 2009 May 12.

PMID:
19435874
[PubMed - indexed for MEDLINE]
Free Article
8.

Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway.

Hu B, Guo P, Bar-Joseph I, Imanishi Y, Jarzynka MJ, Bogler O, Mikkelsen T, Hirose T, Nishikawa R, Cheng SY.

Oncogene. 2007 Aug 16;26(38):5577-86. Epub 2007 Mar 19.

PMID:
17369861
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.

Li Y, Lal B, Kwon S, Fan X, Saldanha U, Reznik TE, Kuchner EB, Eberhart C, Laterra J, Abounader R.

Cancer Res. 2005 Oct 15;65(20):9355-62.

PMID:
16230398
[PubMed - indexed for MEDLINE]
Free Article
10.

Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy.

Li Y, Guessous F, DiPierro C, Zhang Y, Mudrick T, Fuller L, Johnson E, Marcinkiewicz L, Engelhardt M, Kefas B, Schiff D, Kim J, Abounader R.

Mol Cancer Ther. 2009 Feb;8(2):376-85. doi: 10.1158/1535-7163.MCT-08-0627. Epub 2009 Feb 3.

PMID:
19190120
[PubMed - indexed for MEDLINE]
Free Article
11.

HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma.

Bu R, Uddin S, Bavi P, Hussain AR, Al-Dayel F, Ghourab S, Ahmed M, Al-Kuraya KS.

Lab Invest. 2011 Jan;91(1):124-37. doi: 10.1038/labinvest.2010.136. Epub 2010 Jul 26.

PMID:
20661229
[PubMed - indexed for MEDLINE]
Free Article
12.

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.

Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J.

J Natl Cancer Inst. 1999 Sep 15;91(18):1548-56. Erratum in: J Natl Cancer Inst 2000 Jan 5;92(1):78.

PMID:
10491431
[PubMed - indexed for MEDLINE]
Free Article
13.

In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.

Abounader R, Lal B, Luddy C, Koe G, Davidson B, Rosen EM, Laterra J.

FASEB J. 2002 Jan;16(1):108-10. Epub 2001 Nov 29.

PMID:
11729097
[PubMed - indexed for MEDLINE]
Free Article
14.

Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility.

Fang JD, Lee SL.

Biochim Biophys Acta. 2014 Jul;1843(7):1285-94. doi: 10.1016/j.bbamcr.2014.03.020. Epub 2014 Mar 28.

PMID:
24685580
[PubMed - indexed for MEDLINE]
15.

Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.

Wick W, Grimmel C, Wild-Bode C, Platten M, Arpin M, Weller M.

J Neurosci. 2001 May 15;21(10):3360-8.

PMID:
11331365
[PubMed - indexed for MEDLINE]
Free Article
16.

Role of hepatocyte growth factor/c-Met signaling in regulating urokinase plasminogen activator on invasiveness in human hepatocellular carcinoma: a potential therapeutic target.

Lee KH, Choi EY, Hyun MS, Jang BI, Kim TN, Lee HJ, Eun JY, Kim HG, Yoon SS, Lee DS, Kim JH, Kim JR.

Clin Exp Metastasis. 2008;25(1):89-96. Epub 2007 Nov 9.

PMID:
17992475
[PubMed - indexed for MEDLINE]
17.

Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts.

Kim KJ, Wang L, Su YC, Gillespie GY, Salhotra A, Lal B, Laterra J.

Clin Cancer Res. 2006 Feb 15;12(4):1292-8.

PMID:
16489086
[PubMed - indexed for MEDLINE]
Free Article
18.

Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer.

De Bacco F, Luraghi P, Medico E, Reato G, Girolami F, Perera T, Gabriele P, Comoglio PM, Boccaccio C.

J Natl Cancer Inst. 2011 Apr 20;103(8):645-61. doi: 10.1093/jnci/djr093. Epub 2011 Apr 4.

PMID:
21464397
[PubMed - indexed for MEDLINE]
Free Article
19.

Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.

Castro NE, Lange CA.

Breast Cancer Res. 2010;12(4):R60. doi: 10.1186/bcr2622. Epub 2010 Aug 5.

PMID:
20687930
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways.

Bowers DC, Fan S, Walter KA, Abounader R, Williams JA, Rosen EM, Laterra J.

Cancer Res. 2000 Aug 1;60(15):4277-83.

PMID:
10945642
[PubMed - indexed for MEDLINE]
Free Article

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