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Results: 1 to 20 of 105

1.

Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].

Penzo M, Molteni R, Suda T, Samaniego S, Raucci A, Habiel DM, Miller F, Jiang HP, Li J, Pardi R, Palumbo R, Olivotto E, Kew RR, Bianchi ME, Marcu KB.

J Immunol. 2010 Apr 15;184(8):4497-509. doi: 10.4049/jimmunol.0903131. Epub 2010 Mar 15. Erratum in: J Immunol. 2010 Jun 15;184(12):7314.

PMID:
20231695
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.

Kew RR, Penzo M, Habiel DM, Marcu KB.

J Immunol. 2012 Mar 1;188(5):2380-6. doi: 10.4049/jimmunol.1102454. Epub 2012 Jan 27.

PMID:
22287708
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling.

Penzo M, Habiel DM, Ramadass M, Kew RR, Marcu KB.

Biochim Biophys Acta. 2014 Sep;1843(9):1796-804. doi: 10.1016/j.bbamcr.2014.04.011. Epub 2014 Apr 18.

PMID:
24747690
[PubMed - indexed for MEDLINE]
4.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
[PubMed - indexed for MEDLINE]
5.

IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.

Adli M, Merkhofer E, Cogswell P, Baldwin AS.

PLoS One. 2010 Feb 25;5(2):e9428. doi: 10.1371/journal.pone.0009428.

PMID:
20195534
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.

Nottingham LK, Yan CH, Yang X, Si H, Coupar J, Bian Y, Cheng TF, Allen C, Arun P, Gius D, Dang L, Van Waes C, Chen Z.

Oncogene. 2014 Feb 27;33(9):1135-47. doi: 10.1038/onc.2013.49. Epub 2013 Mar 4.

PMID:
23455325
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation.

Luftig M, Yasui T, Soni V, Kang MS, Jacobson N, Cahir-McFarland E, Seed B, Kieff E.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):141-6. Epub 2003 Dec 22.

PMID:
14691250
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein.

Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, Abraham E.

J Biol Chem. 2004 Feb 27;279(9):7370-7. Epub 2003 Dec 4.

PMID:
14660645
[PubMed - indexed for MEDLINE]
Free Article
9.

IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.

Li X, Massa PE, Hanidu A, Peet GW, Aro P, Savitt A, Mische S, Li J, Marcu KB.

J Biol Chem. 2002 Nov 22;277(47):45129-40. Epub 2002 Sep 6.

PMID:
12221085
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes.

Massa PE, Li X, Hanidu A, Siamas J, Pariali M, Pareja J, Savitt AG, Catron KM, Li J, Marcu KB.

J Biol Chem. 2005 Apr 8;280(14):14057-69. Epub 2005 Feb 4.

PMID:
15695520
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation.

Farhana L, Dawson MI, Murshed F, Fontana JA.

Cell Death Differ. 2011 Jan;18(1):164-73. doi: 10.1038/cdd.2010.84. Epub 2010 Jul 30.

PMID:
20671747
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.

Solt LA, Madge LA, May MJ.

J Biol Chem. 2009 Oct 2;284(40):27596-608. doi: 10.1074/jbc.M109.047563. Epub 2009 Aug 7.

PMID:
19666475
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling.

Tanaka H, Fujita N, Tsuruo T.

J Biol Chem. 2005 Dec 9;280(49):40965-73. Epub 2005 Oct 5.

PMID:
16207722
[PubMed - indexed for MEDLINE]
Free Article
15.

Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice.

Tang Y, Reay DP, Salay MN, Mi MY, Clemens PR, Guttridge DC, Robbins PD, Huard J, Wang B.

Gene Ther. 2010 Dec;17(12):1476-83. doi: 10.1038/gt.2010.110. Epub 2010 Aug 19.

PMID:
20720575
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

B-cell CLL/lymphoma 10 (BCL10) is required for NF-kappaB production by both canonical and noncanonical pathways and for NF-kappaB-inducing kinase (NIK) phosphorylation.

Bhattacharyya S, Borthakur A, Tyagi S, Gill R, Chen ML, Dudeja PK, Tobacman JK.

J Biol Chem. 2010 Jan 1;285(1):522-30. doi: 10.1074/jbc.M109.050815. Epub 2009 Nov 6.

PMID:
19897484
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.

Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC.

Mol Cell Biol. 1998 Sep;18(9):5157-65.

PMID:
9710600
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The canonical nuclear factor-κB pathway regulates cell survival in a developmental model of spinal cord motoneurons.

Mincheva S, Garcera A, Gou-Fabregas M, Encinas M, Dolcet X, Soler RM.

J Neurosci. 2011 Apr 27;31(17):6493-503. doi: 10.1523/JNEUROSCI.0206-11.2011.

PMID:
21525290
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues.

Lo JC, Basak S, James ES, Quiambo RS, Kinsella MC, Alegre ML, Weih F, Franzoso G, Hoffmann A, Fu YX.

Blood. 2006 Feb 1;107(3):1048-55. Epub 2005 Sep 29.

PMID:
16195333
[PubMed - indexed for MEDLINE]
Free PMC Article

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