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Results: 1 to 20 of 293

1.

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.

Finberg KE, Whittlesey RL, Fleming MD, Andrews NC.

Blood. 2010 May 6;115(18):3817-26. doi: 10.1182/blood-2009-05-224808. Epub 2010 Mar 3.

PMID:
20200349
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.

Meynard D, Vaja V, Sun CC, Corradini E, Chen S, López-Otín C, Grgurevic L, Hong CC, Stirnberg M, Gütschow M, Vukicevic S, Babitt JL, Lin HY.

Blood. 2011 Jul 21;118(3):747-56. doi: 10.1182/blood-2011-04-348698. Epub 2011 May 26.

PMID:
21622652
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.

Blood. 2009 Sep 17;114(12):2515-20. doi: 10.1182/blood-2009-02-206771. Epub 2009 Jul 21.

PMID:
19622835
[PubMed - indexed for MEDLINE]
Free Article
4.

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

Lenoir A, Deschemin JC, Kautz L, Ramsay AJ, Roth MP, Lopez-Otin C, Vaulont S, Nicolas G.

Blood. 2011 Jan 13;117(2):647-50. doi: 10.1182/blood-2010-07-295147. Epub 2010 Oct 12.

PMID:
20940420
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.

Finberg KE, Whittlesey RL, Andrews NC.

Blood. 2011 Apr 28;117(17):4590-9. doi: 10.1182/blood-2010-10-315507. Epub 2011 Feb 25.

PMID:
21355094
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Low hepcidin accounts for the proinflammatory status associated with iron deficiency.

Pagani A, Nai A, Corna G, Bosurgi L, Rovere-Querini P, Camaschella C, Silvestri L.

Blood. 2011 Jul 21;118(3):736-46. doi: 10.1182/blood-2011-02-337212. Epub 2011 May 31.

PMID:
21628413
[PubMed - indexed for MEDLINE]
Free Article
7.

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Lakhal S, Schödel J, Townsend AR, Pugh CW, Ratcliffe PJ, Mole DR.

J Biol Chem. 2011 Feb 11;286(6):4090-7. doi: 10.1074/jbc.M110.173096. Epub 2010 Oct 21.

PMID:
20966077
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6).

Krijt J, Fujikura Y, Ramsay AJ, Velasco G, Nečas E.

Blood Cells Mol Dis. 2011 Aug 15;47(2):133-7. doi: 10.1016/j.bcmd.2011.04.009. Epub 2011 May 25.

PMID:
21612955
[PubMed - indexed for MEDLINE]
9.

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis.

Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B Jr, Lin HY, Pietrangelo A, Babitt JL.

Gastroenterology. 2009 Oct;137(4):1489-97. doi: 10.1053/j.gastro.2009.06.057. Epub 2009 Jul 7.

PMID:
19591830
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hemojuvelin: a new link between obesity and iron homeostasis.

Luciani N, Brasse-Lagnel C, Poli M, Anty R, Lesueur C, Cormont M, Laquerriere A, Folope V, LeMarchand-Brustel Y, Gugenheim J, Gual P, Tran A, Bekri S.

Obesity (Silver Spring). 2011 Aug;19(8):1545-51. doi: 10.1038/oby.2011.12. Epub 2011 Feb 10.

PMID:
21311510
[PubMed - indexed for MEDLINE]
11.

Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.

Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC.

Blood. 2010 Apr 15;115(15):3136-45. doi: 10.1182/blood-2009-11-251199. Epub 2010 Jan 11. Erratum in: Blood. 2010 Jul 8;116(1):151. Lee, Dai-Hoon [corrected to Lee, Dae-Hoon]; Zhou, Li-Juau [corrected to Zhou, Li-Juan]; Xie, Jiau-Xiu [corrected to Xie, Jian-Xin].

PMID:
20065295
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin.

Krijt J, Fujikura Y, Sefc L, Vokurka M, Hlobenová T, Necas E.

Physiol Res. 2010;59(1):53-9. Epub 2009 Feb 27.

PMID:
19249912
[PubMed - indexed for MEDLINE]
Free Article
13.

Iron-refractory iron deficiency anemia.

Finberg KE.

Semin Hematol. 2009 Oct;46(4):378-86. doi: 10.1053/j.seminhematol.2009.06.006. Review.

PMID:
19786206
[PubMed - indexed for MEDLINE]
14.

Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.

Gkouvatsos K, Wagner J, Papanikolaou G, Sebastiani G, Pantopoulos K.

Hepatology. 2011 Nov;54(5):1800-7. doi: 10.1002/hep.24547. Epub 2011 Aug 24.

PMID:
21748766
[PubMed - indexed for MEDLINE]
15.

Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein.

Zhang AS, Anderson SA, Wang J, Yang F, DeMaster K, Ahmed R, Nizzi CP, Eisenstein RS, Tsukamoto H, Enns CA.

Blood. 2011 Feb 3;117(5):1687-99. doi: 10.1182/blood-2010-06-287292. Epub 2010 Nov 29.

PMID:
21115976
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.

Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P.

Br J Haematol. 2009 Nov;147(4):571-81. doi: 10.1111/j.1365-2141.2009.07873.x. Epub 2009 Sep 8.

PMID:
19751239
[PubMed - indexed for MEDLINE]
17.

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis.

Folgueras AR, de Lara FM, Pendás AM, Garabaya C, Rodríguez F, Astudillo A, Bernal T, Cabanillas R, López-Otín C, Velasco G.

Blood. 2008 Sep 15;112(6):2539-45. doi: 10.1182/blood-2008-04-149773. Epub 2008 Jun 3.

PMID:
18523150
[PubMed - indexed for MEDLINE]
Free Article
18.

Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.

Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE.

Gastroenterology. 2011 Nov;141(5):1907-14. doi: 10.1053/j.gastro.2011.06.077. Epub 2011 Jul 13.

PMID:
21745449
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interacting signals in the control of hepcidin expression.

Darshan D, Anderson GJ.

Biometals. 2009 Feb;22(1):77-87. doi: 10.1007/s10534-008-9187-y. Epub 2009 Jan 8.

PMID:
19130266
[PubMed - indexed for MEDLINE]
20.

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY.

Nat Genet. 2006 May;38(5):531-9. Epub 2006 Apr 9.

PMID:
16604073
[PubMed - indexed for MEDLINE]

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