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Results: 1 to 20 of 131

1.

Nicotine self-administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA.

LeSage MG, Perry JL, Kotz CM, Shelley D, Corrigall WA.

Psychopharmacology (Berl). 2010 Apr;209(2):203-12. doi: 10.1007/s00213-010-1792-0. Epub 2010 Feb 24.

PMID:
20177882
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior.

Plaza-Zabala A, Martín-García E, de Lecea L, Maldonado R, Berrendero F.

J Neurosci. 2010 Feb 10;30(6):2300-10. doi: 10.1523/JNEUROSCI.5724-09.2010.

PMID:
20147556
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hypocretin/orexin signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal.

Plaza-Zabala A, Flores Á, Maldonado R, Berrendero F.

Biol Psychiatry. 2012 Feb 1;71(3):214-23. doi: 10.1016/j.biopsych.2011.06.025. Epub 2011 Aug 10.

PMID:
21831361
[PubMed - indexed for MEDLINE]
4.

Insular hypocretin transmission regulates nicotine reward.

Hollander JA, Lu Q, Cameron MD, Kamenecka TM, Kenny PJ.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19480-5. doi: 10.1073/pnas.0808023105. Epub 2008 Nov 24.

PMID:
19033203
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of orexin/hypocretin in conditioned sucrose-seeking in rats.

Cason AM, Aston-Jones G.

Psychopharmacology (Berl). 2013 Mar;226(1):155-65. doi: 10.1007/s00213-012-2902-y. Epub 2012 Oct 25.

PMID:
23096770
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.

Morairty SR, Revel FG, Malherbe P, Moreau JL, Valladao D, Wettstein JG, Kilduff TS, Borroni E.

PLoS One. 2012;7(7):e39131. doi: 10.1371/journal.pone.0039131. Epub 2012 Jul 2.

PMID:
22768296
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats.

Richards JK, Simms JA, Steensland P, Taha SA, Borgland SL, Bonci A, Bartlett SE.

Psychopharmacology (Berl). 2008 Jul;199(1):109-17. doi: 10.1007/s00213-008-1136-5. Epub 2008 May 10.

PMID:
18470506
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A role for hypocretin/orexin receptor-1 in cue-induced reinstatement of nicotine-seeking behavior.

Plaza-Zabala A, Flores Á, Martín-García E, Saravia R, Maldonado R, Berrendero F.

Neuropsychopharmacology. 2013 Aug;38(9):1724-36. doi: 10.1038/npp.2013.72. Epub 2013 Mar 21.

PMID:
23518606
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers.

Borgland SL, Chang SJ, Bowers MS, Thompson JL, Vittoz N, Floresco SB, Chou J, Chen BT, Bonci A.

J Neurosci. 2009 Sep 9;29(36):11215-25. doi: 10.1523/JNEUROSCI.6096-08.2009.

PMID:
19741128
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system.

España RA, Oleson EB, Locke JL, Brookshire BR, Roberts DC, Jones SR.

Eur J Neurosci. 2010 Jan;31(2):336-48. doi: 10.1111/j.1460-9568.2009.07065.x. Epub 2009 Dec 23.

PMID:
20039943
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The brain orexin system and almorexant in fear-conditioned startle reactions in the rat.

Steiner MA, Lecourt H, Jenck F.

Psychopharmacology (Berl). 2012 Oct;223(4):465-75. Epub 2012 May 17.

PMID:
22592903
[PubMed - indexed for MEDLINE]
12.

Differential effects of the hypocretin 1 receptor antagonist SB 334867 on high-fat food self-administration and reinstatement of food seeking in rats.

Nair SG, Golden SA, Shaham Y.

Br J Pharmacol. 2008 May;154(2):406-16. doi: 10.1038/bjp.2008.3. Epub 2008 Jan 28.

PMID:
18223663
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.

Smith RJ, See RE, Aston-Jones G.

Eur J Neurosci. 2009 Aug;30(3):493-503. doi: 10.1111/j.1460-9568.2009.06844.x. Epub 2009 Jul 28.

PMID:
19656173
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Both orexin receptors are expressed in rat ovaries and fluctuate with the estrous cycle: effects of orexin receptor antagonists on gonadotropins and ovulation.

Silveyra P, Lux-Lantos V, Libertun C.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E977-85. Epub 2007 Jul 17.

PMID:
17638707
[PubMed - indexed for MEDLINE]
Free Article
15.

Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement.

Sharf R, Sarhan M, Brayton CE, Guarnieri DJ, Taylor JR, DiLeone RJ.

Biol Psychiatry. 2010 Apr 15;67(8):753-60. doi: 10.1016/j.biopsych.2009.12.035. Epub 2010 Feb 26.

PMID:
20189166
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Hypocretin-1 dose-dependently modulates maternal behaviour in mice.

D'Anna KL, Gammie SC.

J Neuroendocrinol. 2006 Aug;18(8):553-66.

PMID:
16867176
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system.

Cannella N, Economidou D, Kallupi M, Stopponi S, Heilig M, Massi M, Ciccocioppo R.

Neuropsychopharmacology. 2009 Aug;34(9):2125-34. doi: 10.1038/npp.2009.37. Epub 2009 Mar 25.

PMID:
19322167
[PubMed - indexed for MEDLINE]
Free Article
18.

Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons.

Borgland SL, Storm E, Bonci A.

Eur J Neurosci. 2008 Oct;28(8):1545-56. doi: 10.1111/j.1460-9568.2008.06397.x. Epub 2008 Sep 10.

PMID:
18793323
[PubMed - indexed for MEDLINE]
19.

N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking.

Martin-Fardon R, Weiss F.

Addict Biol. 2014 Mar;19(2):233-6. doi: 10.1111/j.1369-1600.2012.00480.x. Epub 2012 Jul 26.

PMID:
22830647
[PubMed - indexed for MEDLINE]
20.

Evidence for the role of hindbrain orexin-1 receptors in the control of meal size.

Parise EM, Lilly N, Kay K, Dossat AM, Seth R, Overton JM, Williams DL.

Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1692-9. doi: 10.1152/ajpregu.00044.2011. Epub 2011 Sep 28.

PMID:
21957165
[PubMed - indexed for MEDLINE]
Free PMC Article
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