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Items: 1 to 20 of 178


BIN1 localizes the L-type calcium channel to cardiac T-tubules.

Hong TT, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM.

PLoS Biol. 2010 Feb 16;8(2):e1000312. doi: 10.1371/journal.pbio.1000312.


BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.

Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM.

Heart Rhythm. 2012 May;9(5):812-20. doi: 10.1016/j.hrthm.2011.11.055. Epub 2011 Dec 2.


Synopsis. BIN1: a protein with great heart.

Sedwick C.

PLoS Biol. 2010 Feb 16;8(2):e1000311. doi: 10.1371/journal.pbio.1000311. No abstract available.


Disrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.

Tjondrokoesoemo A, Park KH, Ferrante C, Komazaki S, Lesniak S, Brotto M, Ko JK, Zhou J, Weisleder N, Ma J.

PLoS One. 2011;6(9):e25740. doi: 10.1371/journal.pone.0025740. Epub 2011 Sep 30.


Dependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1).

Caldwell JL, Smith CE, Taylor RF, Kitmitto A, Eisner DA, Dibb KM, Trafford AW.

Circ Res. 2014 Dec 5;115(12):986-96. doi: 10.1161/CIRCRESAHA.116.303448. Epub 2014 Oct 20.


Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.

Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM.

Nat Med. 2014 Jun;20(6):624-32. doi: 10.1038/nm.3543. Epub 2014 May 18.


Depletion of T-tubules and specific subcellular changes in sarcolemmal proteins in tachycardia-induced heart failure.

Balijepalli RC, Lokuta AJ, Maertz NA, Buck JM, Haworth RA, Valdivia HH, Kamp TJ.

Cardiovasc Res. 2003 Jul 1;59(1):67-77.


Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.

Tang M, Zhang X, Li Y, Guan Y, Ai X, Szeto C, Nakayama H, Zhang H, Ge S, Molkentin JD, Houser SR, Chen X.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H519-28. doi: 10.1152/ajpheart.00265.2010. Epub 2010 Jun 11.


Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2+ channels.

Polster A, Perni S, Bichraoui H, Beam KG.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):602-6. doi: 10.1073/pnas.1423113112. Epub 2014 Dec 29.


Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.

Fu Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16598-603. doi: 10.1073/pnas.1419129111. Epub 2014 Nov 3.


Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

Zhang C, Chen B, Guo A, Zhu Y, Miller JD, Gao S, Yuan C, Kutschke W, Zimmerman K, Weiss RM, Wehrens XH, Hong J, Johnson FL, Santana LF, Anderson ME, Song LS.

Circulation. 2014 Apr 29;129(17):1742-50. doi: 10.1161/CIRCULATIONAHA.113.008452. Epub 2014 Feb 11.


Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes.

Jaleel N, Nakayama H, Chen X, Kubo H, MacDonnell S, Zhang H, Berretta R, Robbins J, Cribbs L, Molkentin JD, Houser SR.

Circ Res. 2008 Nov 7;103(10):1109-19. doi: 10.1161/CIRCRESAHA.108.185611. Epub 2008 Oct 2.


Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8).

Drum BM, Dixon RE, Yuan C, Cheng EP, Santana LF.

J Mol Cell Cardiol. 2014 Jan;66:63-71. doi: 10.1016/j.yjmcc.2013.10.021. Epub 2013 Nov 9.


Multilayered regulation of cardiac ion channels.

Zhang SS, Shaw RM.

Biochim Biophys Acta. 2013 Apr;1833(4):876-85. doi: 10.1016/j.bbamcr.2012.10.020. Epub 2012 Oct 24. Review.


Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.

Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7636-41. doi: 10.1073/pnas.0902919106. Epub 2009 Apr 21.


{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways.

Wang W, Zhang H, Gao H, Kubo H, Berretta RM, Chen X, Houser SR.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H322-31. doi: 10.1152/ajpheart.00392.2010. Epub 2010 May 21.


AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling.

Pant S, Sharma M, Patel K, Caplan S, Carr CM, Grant BD.

Nat Cell Biol. 2009 Dec;11(12):1399-410. doi: 10.1038/ncb1986. Epub 2009 Nov 15.


BIN1 regulates dynamic t-tubule membrane.

Fu Y, Hong T.

Biochim Biophys Acta. 2015 Nov 11. pii: S0167-4889(15)00380-8. doi: 10.1016/j.bbamcr.2015.11.004. [Epub ahead of print]

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