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Items: 1 to 20 of 79


Phylogenetics applied to genotype/phenotype association and selection analyses with sequence data from angptl4 in humans.

Maxwell TJ, Bendall ML, Staples J, Jarvis T, Crandall KA.

Int J Mol Sci. 2010 Jan 25;11(1):370-85. doi: 10.3390/ijms11010370.


ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial.

Smart-Halajko MC, Kelley-Hedgepeth A, Montefusco MC, Cooper JA, Kopin A, McCaffrey JM, Balasubramanyam A, Pownall HJ, Nathan DM, Peter I, Talmud PJ, Huggins GS; Look AHEAD Study.

BMC Med Genet. 2011 Jun 29;12:89. doi: 10.1186/1471-2350-12-89.


Association studies for next-generation sequencing.

Luo L, Boerwinkle E, Xiong M.

Genome Res. 2011 Jul;21(7):1099-108. doi: 10.1101/gr.115998.110. Epub 2011 Apr 26.


The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk.

Smart-Halajko MC, Robciuc MR, Cooper JA, Jauhiainen M, Kumari M, Kivimaki M, Khaw KT, Boekholdt SM, Wareham NJ, Gaunt TR, Day IN, Braund PS, Nelson CP, Hall AS, Samani NJ, Humphries SE, Ehnholm C, Talmud PJ.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2277-82. doi: 10.1161/ATVBAHA.110.212209. Epub 2010 Sep 9.


A generalized genetic random field method for the genetic association analysis of sequencing data.

Li M, He Z, Zhang M, Zhan X, Wei C, Elston RC, Lu Q.

Genet Epidemiol. 2014 Apr;38(3):242-53. doi: 10.1002/gepi.21790. Epub 2014 Jan 30.


Detecting rare variant effects using extreme phenotype sampling in sequencing association studies.

Barnett IJ, Lee S, Lin X.

Genet Epidemiol. 2013 Feb;37(2):142-51. doi: 10.1002/gepi.21699. Epub 2012 Nov 26.


Genetic variation in ANGPTL4 provides insights into protein processing and function.

Yin W, Romeo S, Chang S, Grishin NV, Hobbs HH, Cohen JC.

J Biol Chem. 2009 May 8;284(19):13213-22. doi: 10.1074/jbc.M900553200. Epub 2009 Mar 7.


Smoothed functional principal component analysis for testing association of the entire allelic spectrum of genetic variation.

Luo L, Zhu Y, Xiong M.

Eur J Hum Genet. 2013 Feb;21(2):217-24. doi: 10.1038/ejhg.2012.141. Epub 2012 Jul 11.


Association testing of clustered rare causal variants in case-control studies.

Lin WY.

PLoS One. 2014 Apr 15;9(4):e94337. doi: 10.1371/journal.pone.0094337. eCollection 2014.


A power set-based statistical selection procedure to locate susceptible rare variants associated with complex traits with sequencing data.

Sun H, Wang S.

Bioinformatics. 2014 Aug 15;30(16):2317-23. doi: 10.1093/bioinformatics/btu207. Epub 2014 Apr 22.


Predicting the functional consequences of non-synonymous DNA sequence variants--evaluation of bioinformatics tools and development of a consensus strategy.

Frousios K, Iliopoulos CS, Schlitt T, Simpson MA.

Genomics. 2013 Oct;102(4):223-8. doi: 10.1016/j.ygeno.2013.06.005. Epub 2013 Jul 3.


Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study.

Nettleton JA, Volcik KA, Demerath EW, Boerwinkle E, Folsom AR.

Ann Epidemiol. 2008 Nov;18(11):842-6. doi: 10.1016/j.annepidem.2008.07.004. Epub 2008 Sep 21.


New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome.

Yang RQ, Jabbari J, Cheng XS, Jabbari R, Nielsen JB, Risgaard B, Chen X, Sajadieh A, Haunsø S, Svendsen JH, Olesen MS, Tfelt-Hansen J.

BMC Genet. 2014 Jun 18;15:74. doi: 10.1186/1471-2156-15-74.


Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence.

Hoehe MR, Köpke K, Wendel B, Rohde K, Flachmeier C, Kidd KK, Berrettini WH, Church GM.

Hum Mol Genet. 2000 Nov 22;9(19):2895-908.


An evolutionary framework for association testing in resequencing studies.

King CR, Rathouz PJ, Nicolae DL.

PLoS Genet. 2010 Nov 11;6(11):e1001202. doi: 10.1371/journal.pgen.1001202.


A fast and noise-resilient approach to detect rare-variant associations with deep sequencing data for complex disorders.

Cheung YH, Wang G, Leal SM, Wang S.

Genet Epidemiol. 2012 Nov;36(7):675-85. doi: 10.1002/gepi.21662. Epub 2012 Aug 3.


Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.

Deo RC, Reich D, Tandon A, Akylbekova E, Patterson N, Waliszewska A, Kathiresan S, Sarpong D, Taylor HA Jr, Wilson JG.

PLoS Genet. 2009 Jan;5(1):e1000342. doi: 10.1371/journal.pgen.1000342. Epub 2009 Jan 16.


Adaptive ridge regression for rare variant detection.

Zhan H, Xu S.

PLoS One. 2012;7(8):e44173. doi: 10.1371/journal.pone.0044173. Epub 2012 Aug 28.


Patterns of association between PPARgamma genetic variation and indices of adiposity and insulin action in African-Americans and whites: the CARDIA Study.

Wei Q, Jacobs DR Jr, Schreiner PJ, Siscovick DS, Steffes MW, Fornage M.

J Mol Med (Berl). 2006 Nov;84(11):955-65. Epub 2006 Sep 6.

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